Clinical trials
Peripheral Neuropathic Pain clinical trials
Below are recruiting peripheral neuropathic pain clinical trials, each written for real people, not researchers. We’re tracking 78 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07352514Recruiting
Natural supplements and exercise for chemo nerve pain
This study tests if a combination of two natural supplements (PEA and Scutellaria) plus a specific exercise program can help reduce nerve pain caused by chemotherapy. It is for people who have had chemotherapy in the last 6 months and still have moderate to severe nerve pain.
Palermo, ItaliaAges 18 years+ - NCT06980948RecruitingPhase 1/Phase 2
Gene therapy study for nerve pain from small fiber neuropathy
This trial tests a new gene therapy called ST-503 for people with long-lasting nerve pain from small fiber neuropathy that hasn't improved with standard treatments. The study will check if the treatment is safe and tolerable.
Scottsdale, ArizonaAges 18 years+ - NCT07250828Enrolling by invitation
BurstDR spinal cord stimulation for painful diabetic neuropathy
This trial tests a type of spinal cord stimulation called BurstDR to see if it can reduce pain from diabetic nerve damage. It may help people with diabetes who have ongoing leg pain that hasn't gotten better with standard pain medications.
Grand Island, NebraskaAges 19 years+ - NCT05645003Recruiting
Brain stimulation therapy for nerve pain after spinal cord injury
This trial tests whether painless magnetic stimulation of the brain (non-surgical) can reduce long-lasting nerve pain after spinal cord injury. It may help people whose spinal cord injury-related pain has been present for at least six months.
AfyonkarahisarAges 20–70 - NCT07403331Recruiting
Nerve pain in legs: spinal cord stimulation plus team care
This trial tests a treatment bundle that combines a spinal cord stimulator (a device that sends mild electrical pulses to your spine to block pain signals) with a team of specialists (like a psychologist and physical therapist) to reduce chronic nerve pain in the legs and improve your ability to move and function.
OsloAges 18–60 - NCT07855445Recruiting
Nerve pain and MRI findings in lumbar spinal stenosis
This study looks at how nerve pain relates to MRI results in people with lumbar spinal stenosis, a condition where the spinal canal narrows and presses on nerves. It aims to better understand the link between symptoms and imaging, which could help improve care.
Istanbul, IstanbulAges 18 years+ - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT06596681RecruitingEarly Phase 1
Study of GA for hard-to-treat nerve pain
This early-phase trial tests a new treatment called GA for people with hard-to-treat neuropathic pain that hasn't improved with standard therapies. The goal is to see if it is safe and tolerable.
Beijing, Beijing MunicipalityAges 18–65 - NCT06185816RecruitingPhase 2/Phase 3
Non-invasive pulsed radiofrequency for nerve pain
This trial tests a non-invasive treatment called pulsed radiofrequency for people with chronic nerve pain after an injury. It uses a device that sends short bursts of energy to the painful area to help reduce pain without surgery.
Redwood City, CaliforniaAges 18 years+ - NCT05701852Recruiting
Study brain scans during tasks in chronic nerve pain
This study looks at how brain activity changes in people with long-lasting nerve pain using an MRI scan while you do simple behavioral tasks. It may help researchers understand brain function in chronic neuropathic pain and how it affects day-to-day abilities.
ParisAges 18 years+ - NCT03852381Recruiting
Spinal cord stimulation for nerve pain after back surgery
This study looks at how spinal cord stimulation (a device that sends mild signals to the spinal cord) affects nerve pain after lumbar surgery. It also aims to help predict who is most likely to improve and why, comparing patients with and without certain sensory symptoms.
Toronto, OntarioAges 18–80 - NCT05483816Recruiting
Sensory stimulation trial for nerve pain in people with neuropathy
This study tests a multi-sensory (multiple-sense) stimulation approach to see if it can help people with nerve-related pain in the legs/feet. You must be able to safely take part in MRI-related sessions and answer questions about pain and health history.
Zurich, Canton of ZurichAges 18–80 - NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64 - NCT06880484Enrolling by invitation
Far-infrared socks for diabetic nerve pain
This study tests whether special far-infrared socks can help relieve nerve pain and improve nerve function in people with diabetic nerve damage. If you have mild to moderate nerve pain and live in Kayseri, you may be able to join.
Talas, KayseriAges 19 years+ - NCT05623111RecruitingPhase 2
Nerve-area Botox shots for diabetic foot nerve pain
This Phase 2 trial tests whether injecting incobotulinumtoxin-A near painful nerves can reduce nerve-type pain in the feet for people with diabetes. If you have lasting, fairly symmetrical pain in both feet, the injections may help calm the nerve pain signals.
Glostrup MunicipalityAges 18 years+ - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT07602387Recruiting
Capsaicin cream for chemo-related nerve pain in legs
This study tests whether an 8% capsaicin cream (a chili-pepper derived treatment) can help reduce nerve pain and numbness in the legs caused by cancer chemotherapy drugs (taxanes). The cream is applied directly to affected areas, and the research team will track whether it improves your symptoms and pain levels over time.
Boulogne-Billancourt, HAUTS DE SEINEAges 18 years+ - NCT06264297Recruiting
Nerve radiofrequency treatment for chronic leg pain
This trial tests a new type of treatment (high-voltage pulsed radiofrequency) that uses a special needle to deliver energy to the nerve root in your lower back. The goal is to see if it can reduce chronic leg pain caused by a pinched or irritated nerve.
Terrassa, BarcelonaAges 18 years+ - NCT07844772Recruiting
Psoriasis treatment and nerve pain study
This study looks at how different psoriasis treatments affect nerve-related pain and sensitivity. It compares patients on biologic injections, standard pills, or creams to see if treatment type matters for pain and skin symptoms.
Istanbul, IstanbulAges 18 years+ - NCT07377305Recruiting
Brain stimulation for nerve pain in NMOSD
This trial tests a new, non-invasive brain stimulation method (tTIS) to treat chronic nerve pain in people with neuromyelitis optica spectrum disorder (NMOSD). It aims to see if this treatment is safe and can reduce pain without surgery or drugs.
Xi'an, ShaanxiAges 18–75 - NCT05817786Recruiting
Electrical nerve stimulation for persistent arm nerve pain
This trial tests whether stimulating the nerve roots in the shoulder area can reduce long-lasting nerve pain in one arm. It may help people whose arm pain has not improved with standard nerve-pain treatments.
Lyon, FranceAges 1.5 years–80 years - NCT05786599RecruitingPhase 2/Phase 3
Low-dose methadone for chemotherapy nerve pain
This trial studies whether methadone can reduce painful nerve damage caused by certain chemotherapy drugs. It is for adults who have ongoing nerve pain for months after chemotherapy ended and may help by lowering neuropathic (nerve) pain.
Nanaimo, British ColumbiaAges 19 years+ - NCT05720065RecruitingPhase 2
Testing botulinum toxin A for jaw muscle pain
This trial studies whether botulinum toxin A (a type of muscle-relaxing medicine) can reduce jaw muscle pain and help explain why it happens. It focuses on people with specific jaw muscle pain patterns and tests outcomes after injection/biopsy.
Huddinge, Stockholm CountyAges 20–45 - NCT07739303Recruiting
Nerve block comparison for shoulder surgery
This study compares two types of numbing injections (nerve blocks) given before shoulder surgery to see which one provides better pain relief while keeping your diaphragm (the muscle that helps you breathe) working well.
Yenimahalle, AnkaraAges 18–65
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Common questions
- Are there clinical trials for peripheral neuropathic pain?
- Yes. Clin2 currently lists 78 recruiting peripheral neuropathic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral neuropathic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral neuropathic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.