Clinical trials
Peripheral Neuropathic Pain clinical trials
Below are recruiting peripheral neuropathic pain clinical trials, each written for real people, not researchers. We’re tracking 77 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06980948RecruitingPhase 1/Phase 2
Gene therapy study for nerve pain from small fiber neuropathy
This trial tests a new gene therapy called ST-503 for people with long-lasting nerve pain from small fiber neuropathy that hasn't improved with standard treatments. The study will check if the treatment is safe and tolerable.
Scottsdale, ArizonaAges 18 years+ - NCT07250828Enrolling by invitation
BurstDR spinal cord stimulation for painful diabetic neuropathy
This trial tests a type of spinal cord stimulation called BurstDR to see if it can reduce pain from diabetic nerve damage. It may help people with diabetes who have ongoing leg pain that hasn't gotten better with standard pain medications.
Grand Island, NebraskaAges 19 years+ - NCT05645003Recruiting
Brain stimulation therapy for nerve pain after spinal cord injury
This trial tests whether painless magnetic stimulation of the brain (non-surgical) can reduce long-lasting nerve pain after spinal cord injury. It may help people whose spinal cord injury-related pain has been present for at least six months.
AfyonkarahisarAges 20–70 - NCT03037684Recruiting
Electrical skin stimulation for nerve and chronic pain
This trial tests whether painless electrical stimulation through the skin can reduce neuropathic pain or long-lasting pain after surgery. It may help some people by changing how pain signals travel in the nervous system.
NottwilAges 18–65 - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT06596681RecruitingEarly Phase 1
Study of GA for hard-to-treat nerve pain
This early-phase trial tests a new treatment called GA for people with hard-to-treat neuropathic pain that hasn't improved with standard therapies. The goal is to see if it is safe and tolerable.
Beijing, Beijing MunicipalityAges 18–65 - NCT06185816RecruitingPhase 2/Phase 3
Non-invasive pulsed radiofrequency for nerve pain
This trial tests a non-invasive treatment called pulsed radiofrequency for people with chronic nerve pain after an injury. It uses a device that sends short bursts of energy to the painful area to help reduce pain without surgery.
Redwood City, CaliforniaAges 18 years+ - NCT03852381Recruiting
Spinal cord stimulation for nerve pain after back surgery
This study looks at how spinal cord stimulation (a device that sends mild signals to the spinal cord) affects nerve pain after lumbar surgery. It also aims to help predict who is most likely to improve and why, comparing patients with and without certain sensory symptoms.
Toronto, OntarioAges 18–80 - NCT05701852Recruiting
Study brain scans during tasks in chronic nerve pain
This study looks at how brain activity changes in people with long-lasting nerve pain using an MRI scan while you do simple behavioral tasks. It may help researchers understand brain function in chronic neuropathic pain and how it affects day-to-day abilities.
ParisAges 18 years+ - NCT05483816Recruiting
Sensory stimulation trial for nerve pain in people with neuropathy
This study tests a multi-sensory (multiple-sense) stimulation approach to see if it can help people with nerve-related pain in the legs/feet. You must be able to safely take part in MRI-related sessions and answer questions about pain and health history.
Zurich, Canton of ZurichAges 18–80 - NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64 - NCT06880484Enrolling by invitation
Far-infrared socks for diabetic nerve pain
This study tests whether special far-infrared socks can help relieve nerve pain and improve nerve function in people with diabetic nerve damage. If you have mild to moderate nerve pain and live in Kayseri, you may be able to join.
Talas, KayseriAges 19 years+ - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT05623111RecruitingPhase 2
Nerve-area Botox shots for diabetic foot nerve pain
This Phase 2 trial tests whether injecting incobotulinumtoxin-A near painful nerves can reduce nerve-type pain in the feet for people with diabetes. If you have lasting, fairly symmetrical pain in both feet, the injections may help calm the nerve pain signals.
Glostrup MunicipalityAges 18 years+ - NCT07416448Recruiting
Pain treatment for nerve-related pain after combat injury
This study tests a procedure to treat pain from nerve damage (neuroma) after a combat injury. It aims to help people with moderate to severe pain that comes from a specific nerve.
RivneAges 18 years+ - NCT07602387Recruiting
Capsaicin cream for chemo-related nerve pain in legs
This study tests whether an 8% capsaicin cream (a chili-pepper derived treatment) can help reduce nerve pain and numbness in the legs caused by cancer chemotherapy drugs (taxanes). The cream is applied directly to affected areas, and the research team will track whether it improves your symptoms and pain levels over time.
Boulogne-Billancourt, HAUTS DE SEINEAges 18 years+ - NCT05817786Recruiting
Electrical nerve stimulation for persistent arm nerve pain
This trial tests whether stimulating the nerve roots in the shoulder area can reduce long-lasting nerve pain in one arm. It may help people whose arm pain has not improved with standard nerve-pain treatments.
Lyon, FranceAges 1.5 years–80 years - NCT06264297Recruiting
Nerve radiofrequency treatment for chronic leg pain
This trial tests a new type of treatment (high-voltage pulsed radiofrequency) that uses a special needle to deliver energy to the nerve root in your lower back. The goal is to see if it can reduce chronic leg pain caused by a pinched or irritated nerve.
Terrassa, BarcelonaAges 18 years+ - NCT06479577Recruiting
Comparing ultrasound and laser therapy for diabetic foot pain
This study compares two physical therapy methods (ultrasound and high-intensity laser therapy) to see which one better reduces nerve pain, improves strength, and boosts quality of life in people with diabetic foot pain.
Bahawalpur, Punjab ProvinceAges 50–75 - NCT07377305Recruiting
Brain stimulation for nerve pain in NMOSD
This trial tests a new, non-invasive brain stimulation method (tTIS) to treat chronic nerve pain in people with neuromyelitis optica spectrum disorder (NMOSD). It aims to see if this treatment is safe and can reduce pain without surgery or drugs.
Xi'an, ShaanxiAges 18–75 - NCT05786599RecruitingPhase 2/Phase 3
Low-dose methadone for chemotherapy nerve pain
This trial studies whether methadone can reduce painful nerve damage caused by certain chemotherapy drugs. It is for adults who have ongoing nerve pain for months after chemotherapy ended and may help by lowering neuropathic (nerve) pain.
Nanaimo, British ColumbiaAges 19 years+ - NCT05720065RecruitingPhase 2
Testing botulinum toxin A for jaw muscle pain
This trial studies whether botulinum toxin A (a type of muscle-relaxing medicine) can reduce jaw muscle pain and help explain why it happens. It focuses on people with specific jaw muscle pain patterns and tests outcomes after injection/biopsy.
Huddinge, Stockholm CountyAges 20–45 - NCT06540456Enrolling by invitation
Capsaicin patch for nerve-related lower back pain
This study tests a medicated patch called Qutenza (capsaicin) to treat chronic lower back pain that involves nerve damage. The patch is placed on the skin to help reduce pain signals.
Summerville, South CarolinaAges 18 years+ - NCT05706103Recruiting
Exercise therapy for recurrent low back pain with brain changes
This trial studies whether a specific exercise program can improve recurrent low back pain by changing activity in muscles and the brain. If you have non-specific low back pain that comes and goes over time, you may be asked to do exercises and undergo brain and muscle testing (including MRI).
Ghent, Oost-VlaanderenAges 18–45
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Common questions
- Are there clinical trials for peripheral neuropathic pain?
- Yes. Clin2 currently lists 77 recruiting peripheral neuropathic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral neuropathic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral neuropathic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.