Clinical trials
Pilot Study clinical trials
Below are recruiting pilot study clinical trials, each written for real people, not researchers. We’re tracking 495 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05721976Recruiting
Grandmother–daughter lifestyle program for certain cancer survivors
This pilot study tests a supportive program for grandmothers who finished breast, endometrial, or ovarian cancer treatment and their adult daughters. It aims to encourage healthier habits, including physical activity, using phone-based support and Spanish/English materials.
Miami, FloridaAges 21 years+ - NCT05726396RecruitingPhase 2
Microbiome therapy for steroid-resistant immune colitis
This Phase 2 pilot study tests a “restorative microbiota therapy” (RMT) to treat colitis caused by immune checkpoint inhibitors when standard treatments like steroids are not working. It aims to see if this approach is safe and practical, and may improve diarrhea and gut inflammation.
Brainerd, MinnesotaAges 18 years+ - NCT01484730Recruiting
Imaging study during blocked blood flow
This is a small study testing special camera imaging (including laser-based methods) to see what happens in blood vessels when blood flow is temporarily blocked. It may help researchers improve how they measure and understand blood flow problems.
Irvine, CaliforniaAges 18 years+ - NCT04166526Recruiting
Brain and brain-vessel MRI study in kids with sickle cell
This study uses MRI scans to understand how the brain and blood vessels are affected in children with sickle cell disease, including before and after certain treatments. It also includes healthy children for comparison and may help improve future monitoring and care.
Boston, MassachusettsAges 8–18 - NCT05508633Enrolling by invitationPhase 2
Alverine test to lower high pressure in the liver
This trial studies alverine to lower portal hypertension, which is high blood pressure in the liver that can happen with cirrhosis. If it works safely, it may reduce pressure-related complications in people with confirmed liver scarring.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05485155RecruitingPhase 2
Zemaira trial for adults with eosinophilic esophagus
This Phase 2 study tests Zemaira (an alpha-1 antitrypsin treatment given through an IV) to see if it improves eosinophilic esophagitis (EoE) in adults. You may be able to help researchers learn whether this treatment can reduce EoE activity when standard treatments haven’t worked.
Bethesda, MarylandAges 18–70 - NCT05290857Recruiting
Blood thinner safety after gastrointestinal bleeding
This study looks at how to safely restart blood thinners after a major gastrointestinal bleed, specifically for people with atrial fibrillation or blood clots. It aims to find the best timing and approach to prevent future strokes or clots while avoiding another bleed.
Calgary, AlbertaAges 18 years+ - NCT05254041Recruiting
Testing suction to help remove an IUD with a menstrual cup
This study looks at whether gentle suction can help safely remove an IUD when using a menstrual cup at the same time. It may help if your IUD needs removal, and the researchers are testing a specific removal method.
Denver, ColoradoAges 18–45 - NCT05229224Recruiting
Study of a new device for frequent tension headaches
This pilot study tests a device approach (“Osteo-Fluidic-Sensitive”) for people who get frequent episodic tension-type headaches. It aims to see whether the device is safe and can reduce headache burden for the right kind of headache pattern.
PoitiersAges 18–75 - NCT05151822Recruiting
Virtual reality during awake orthopedic or brain surgery
This pilot study tests whether a virtual reality (VR) headset can be used safely while you have certain types of surgery while you are awake or lightly sedated with local numbing. The goal is to see if VR can fit into surgery care for appropriate patients.
BrestAges 18–75 - NCT05160480Enrolling by invitation
Total-body PET scan using FDA-approved tracers for prostate or NET cancer
This pilot study tests a total-body PET scan with approved tracer medicines to help detect cancer spread in people with suspected metastatic prostate cancer or certain neuroendocrine tumors (NETs). You may be able to join if recent scans already suggest metastasis and you can safely complete the scan timing and positioning.
Sacramento, CaliforniaAges 18 years+ - NCT05171244Recruiting
Virtual reality training for kids with autism
This study tests whether immersive virtual reality (VR) training can improve how children with autism process different sensory information (like sights and sounds). It will compare children who do the VR training with another group as part of a pilot study at a child psychiatry center.
Tours, ToursAges 8–16 - NCT05090722Recruiting
PureWick Device for Nighttime Urination in Women
This study tests a device called PureWick that helps manage frequent nighttime urination in women. If you wake up 2+ times per night to urinate, this trial explores whether the device can improve your sleep and quality of life.
New York, New YorkAges 50 years+ - NCT05041569Recruiting
MRI study of brain vein damage and swelling patterns
This pilot study uses an MRI scan that involves an injected contrast to look at how brain blood-flow pathways are being blocked or narrowed. The goal is to better understand the kind of damage caused by these vein problems, which may help doctors monitor and plan care.
Paris, ParisAges 18 years+ - NCT04947657Recruiting
Atrial fibrillation blood and heart scan pilot during ablation
This study looks at blood-related “clotting” signs and heart scan results in people with atrial fibrillation (AF) who are getting a catheter ablation. It may help doctors better understand AF and choose treatments more precisely.
New Orleans, LouisianaAges 18–120 - NCT04899037Recruiting
Long-term follow-up for people using an implanted hearing device
This study checks how well long-term care works for people who may use an osseointegrated hearing device (an implanted option that connects to bone). It may help by improving long-term support and outcomes for hearing and day-to-day functioning over about three years.
Tampa, FloridaAges 18–85 - NCT04814420Recruiting
Study heart scarring in sleep apnea, with or without atrial fibrillation
This pilot study looks at whether obstructive sleep apnea leads to heart scarring (called atrial fibrosis), especially in people with and without an irregular heart rhythm (atrial fibrillation). It may help researchers understand who is at higher risk and why, using sleep testing and heart imaging.
New Orleans, LouisianaAges 18–75 - NCT04701723Recruiting
Breathing training to help after trauma stress
This pilot study tests whether “cardiac coherence” breathing exercises can help prevent ongoing (chronic) post-traumatic stress disorder after a recent traumatic event. It’s meant for people who are newly dealing with an acute stress reaction, soon after the event.
Saint-PaulAges 18 years+ - NCT04764331Recruiting
Red light cap for scar-forming hair loss in women
This pilot study tests an “all LED” red light cap to treat central centrifugal cicatricial alopecia (CCCA), a type of scarring hair loss. If you’re a woman with confirmed CCCA at Stage II–III and stable treatment, the study may help see whether red light can improve your hair loss without changing your current plan.
Winston-Salem, North CarolinaAges 18–75 - NCT04746820Recruiting
Brain monitoring in unconscious ICU patients after cardiac arrest
This trial tests a bedside brain-monitoring method (near-infrared light and EEG) in people who are unconscious after severe brain injury from cardiac arrest. The goal is to see whether it can help measure brain function during the first week after admission.
Zurich, Canton of ZurichAges 18 years+ - NCT04655404RecruitingEarly Phase 1
Larotrectinib for children with newly diagnosed glioma with NTRK fusion
This trial tests larotrectinib, a targeted cancer medicine, in children and teens with newly diagnosed high-grade brain glioma that has an NTRK fusion. It may help shrink or control tumors by targeting a specific genetic change in the cancer.
Aurora, ColoradoAges Up to 21 years - NCT04512716RecruitingEarly Phase 1
Radioimmunotherapy then CD19 CAR T for hard-to-treat blood cancers
This early-phase study tests a two-step treatment: first a targeted radioactive antibody (131-I apamistamab) and then CD19 CAR T-cell therapy. It is for adults with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL) or diffuse large B-cell lymphoma (DLBCL) that is not responding or has come back, aiming to shrink cancer using engineered immune cells.
Basking Ridge, New JerseyAges 18 years+ - NCT04571736Recruiting
Web and video support during thyroid surgery planning
This study tests a pre-surgery video support program and a secure website to help people prepare for thyroid surgery. It may improve understanding and follow-through by collecting your answers before the operation.
Montpellier, HéraultAges 18–75 - NCT04399876Enrolling by invitationPhase 1
Testing an implantable device to study drug response in prostate cancer
This early-phase study uses a tiny implant placed during prostate cancer surgery planning to help researchers measure how tumors respond to treatment while still in the body. The results may help improve future treatment choices for men with intermediate- or high-risk prostate cancer.
Boston, MassachusettsAges 22 years+
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Common questions
- Are there clinical trials for pilot study?
- Yes. Clin2 currently lists 495 recruiting pilot study studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pilot study trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pilot study trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.