Clinical trials
Pilot Study clinical trials
Below are recruiting pilot study clinical trials, each written for real people, not researchers. We’re tracking 496 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04399876Enrolling by invitationPhase 1
Testing an implantable device to study drug response in prostate cancer
This early-phase study uses a tiny implant placed during prostate cancer surgery planning to help researchers measure how tumors respond to treatment while still in the body. The results may help improve future treatment choices for men with intermediate- or high-risk prostate cancer.
Boston, MassachusettsAges 22 years+ - NCT04393701Recruiting
Testing newborn blood spots to check for rare storage diseases
This pilot study tries a systematic way to look for several rare “lysosomal storage” diseases in newborns using a specialized lab test on routine blood samples. It may help detect these conditions earlier so treatment can start sooner if needed.
CaenAges 1 day–4 days - NCT04180085RecruitingPhase 2
Belatacept to protect kidneys in heart transplant patients
This trial studies whether belatacept can be used after a heart transplant to help protect kidney function over time. It focuses on people who already have (or are at risk for) worsening kidney function after transplant, while avoiding those with certain infections or rejection concerns.
BordeauxAges 18 years+ - NCT04191512Recruiting
Comparing two treatments for sleep apnea
This study compares two common treatments for moderate to severe sleep apnea: a device that keeps your airway open during sleep and a machine that delivers air pressure. It aims to see which works better for people like you.
Philadelphia, PennsylvaniaAges 22 years+ - NCT04253964RecruitingPhase 2
Chemotherapy plus immunotherapy for advanced lung cancer
This study tests a combination of chemotherapy and immunotherapy in people with advanced non-small cell lung cancer that has spread or cannot be removed with surgery. The goal is to see how well this treatment works in patients with different levels of daily activity.
Charlotte, North CarolinaAges 18 years+ - NCT04068012Recruiting
Test of a decision support tool for children with PARDS
This trial tests a computer “decision support” tool to help the care team manage treatment for children with PARDS who are just starting a breathing machine. It may help clinicians choose care steps and potentially support safer, more effective breathing management during the first days of ventilation.
Chicago, IllinoisAges 1 month–18 years - NCT04047784Enrolling by invitation
Using EBUS to help diagnose a blood clot in the lungs
This study looks at whether a procedure called EBUS (a camera passed through the airway) can help doctors diagnose an acute pulmonary embolism—a sudden blood clot in the lungs—in critically ill, intubated ICU patients. If you’re eligible, EBUS may be done during bronchoscopy as part of your usual care to help confirm or rule out the diagnosis.
Los Angeles, CaliforniaAges 18 years+ - NCT04107181Recruiting
Speculum-free screening for cervical cancer testing
This pilot study tests a new way to check for cervical cancer that does not use a speculum (a tool used during pelvic exams). If you qualify, you may be offered this alternative screening method as part of the study.
Durham, North CarolinaAges 21–65 - NCT04041713RecruitingPhase 2
Antioxidant drink trial for children with Rett syndrome
This Phase 2 trial studies whether an antioxidant “cocktail” helps children and teens with Rett syndrome compared with a placebo (inactive drink). If you join, you’ll get study assessments and blood tests to see if the treatment is safe and helpful.
Toronto, OntarioAges 2–21 - NCT03990909Recruiting
BCAA supplements to help improve sleep
This pilot study tests whether taking BCAA supplements can improve sleep problems. You may be able to join if you’re a veteran with sleep issues and can do the study by phone.
Portland, OregonAges 18–89 - NCT03862417Recruiting
Exercise program for adults with degenerative scoliosis pain
This pilot study tests an exercise program to help reduce pain and improve function in adults over 50 with degenerative scoliosis. It may be helpful if your spine curve is in a moderate range and you’re not recently had certain injections or surgery.
Edmonton, AlbertaAges 50 years+ - NCT03610906Enrolling by invitation
Study of blood/tissue targets in suspected childhood brain tumors
This study looks at biological “targets” (things in the body) to help guide future medical treatments for children and teens with suspected craniopharyngioma. It will collect and analyze tissue samples from planned care to understand what therapies might work best.
Aurora, ColoradoAges 4 weeks–21 years - NCT03582800RecruitingPhase 2
Sodium thiosulfate shots for abnormal calcium or bone spots
This pilot study tests a medicine called sodium thiosulfate (given as a skin shot) to treat abnormal calcium or bone formation in places they don’t belong. It’s meant for people whose condition is causing significant problems, and who are not planning surgery for the next year.
BordeauxAges 6 months+ - NCT03201094Recruiting
NMES and whey protein for recovery after aneurysmal brain bleed
This pilot study tests whether a therapy that gently stimulates nerves (NMES) and a whey-protein supplement (HPRO) can improve recovery after an aneurysmal subarachnoid hemorrhage (SAH), a type of bleeding around the brain. Participants are usually treated soon after the bleed and stay in the ICU long enough for the study measures.
Baltimore, MarylandAges 18 years+ - NCT02526368RecruitingEarly Phase 1
Scan your prostate with special MRI using pyruvate to find high-grade cancer
This trial tests whether a specialized MRI scan using a pyruvate tracer can better detect high-grade (more aggressive) prostate cancer. It may help doctors find cancer more accurately and guide treatment decisions or targeted follow-up.
San Francisco, CaliforniaAges 18 years+ - NCT01297400RecruitingPhase 2
Testing a topical treatment for thermal burns
This trial studies whether a topical medicine (MW-III) is safe and helps heal thermal burns. It is for adults with relatively limited burn size and certain burn depths, while excluding infected or high-risk wounds.
Phoenix, ArizonaAges 18 years+ - NCT01771718Recruiting
Non-invasive skin imaging study using a special microscope
This is a pilot research study that uses a non-invasive skin imaging technique to look at skin details using multiphoton microscopy. It may help researchers improve how skin is studied, without needing surgery or injections in most cases.
Irvine, CaliforniaAges Any age - NCT01127854Enrolling by invitation
Study genes in people with calcium kidney stones
This pilot study looks at how certain gene changes may contribute to calcium oxalate kidney stones. You may be asked for a blood sample and a questionnaire, whether you have a history of stones or not (as a comparison group).
Jacksonville, FloridaAges 18 years+ - NCT07402577Recruiting
Pain and opioid use in young sarcoma survivors
This study looks at pain and opioid use in adolescents and young adults who have had sarcoma. It uses a smartphone app to track symptoms over 3 months to better understand cancer-related pain.
Buffalo, New YorkAges 12–70 - NCT06564025Recruiting
Online sexual health program for fathers and teens
This study tests an online program to help fathers and their teenage children talk about sexual health. It involves surveys, interactive activities, and an online support group, all done from home.
Wellesley, MassachusettsAges 14 years+ - NCT07072286Recruiting
Regional anesthesia for pelvic fracture pain relief
This study tests whether regional anesthesia techniques, which numb the area around your pelvic fracture, can better manage your pain while you wait for surgery. It aims to see if these methods improve pain relief and reduce the need for other pain medicines.
TurinAges 18 years+ - NCT05030545RecruitingPhase 4
PET/CT study of spironolactone or eplerenone in primary aldosteronism
This study looks at how primary aldosteronism affects the heart and blood vessels, and whether blocking its hormone signal (with spironolactone or eplerenone) changes those findings on imaging tests. It is small and focuses on people with confirmed or suspected primary aldosteronism who are being followed for heart health.
Boston, MassachusettsAges 18–85 - NCT07777484RecruitingPhase 1
Study of TRB-001 vaccine for Parkinson's disease after prior immunotherapy
This study tests an experimental vaccine called TRB-001 in people with Parkinson's disease who have already received a previous immunotherapy targeting alpha-synuclein. The goal is to see if the vaccine is safe and how it affects the immune system and the disease.
ViennaAges 18 years+ - NCT07620808Enrolling by invitation
Medically-Tailored Meals and Heart Health Study
This study tests whether personalized meal plans designed by doctors can help people with type 2 diabetes and high blood pressure improve their heart health. You'll receive specially prepared meals for 8 months and answer questions about your health.
New York, New YorkAges 20 years+
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Common questions
- Are there clinical trials for pilot study?
- Yes. Clin2 currently lists 496 recruiting pilot study studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pilot study trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pilot study trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.