Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,904 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06363994RecruitingPhase 3
Study of orelabrutinib plus BR for untreated mantle cell lymphoma
This trial tests a new combination of drugs (orelabrutinib plus BR) compared to BR alone for people with newly diagnosed mantle cell lymphoma who have not had treatment before. It may be an option if you are older or not able to have a stem cell transplant.
BeijingAges 60 years+ - NCT07535307RecruitingPhase 1
Testing NNC0487-0111 to regulate insulin in type 2 diabetes
This early-stage study tests a new experimental drug (NNC0487-0111) designed to help regulate insulin levels in adults with type 2 diabetes. Researchers want to see if it works safely and effectively when combined with your current diabetes medications.
NeussAges 18–75 - NCT07540910RecruitingPhase 1
Safety study of EDP-978 in healthy adults
This is an early-stage study testing a new experimental drug called EDP-978 in healthy volunteers to see if it is safe and how the body processes it. Researchers will give participants single or multiple doses and monitor for side effects and how the drug moves through the body.
San Antonio, TexasAges 18–65 - NCT07540988RecruitingPhase 3
Testing Nerandomilast for Scarring Lung Disease
This study tests whether a new drug called nerandomilast can slow down scarring in the lungs for people with certain types of fibrosing interstitial lung disease (a condition where lung tissue becomes thick and scarred). You may qualify if you have lung scarring that is getting worse and haven't tried this or similar drugs before.
Birmingham, AlabamaAges 18 years+ - NCT07538830Recruiting
Probiotic supplement for muscle strength in older adults
This study tests whether a specific probiotic (a beneficial bacteria called Lactiplantibacillus plantarum) can help improve muscle strength and physical function in adults aged 50–84. The probiotic may work by improving gut health, which could support muscle health.
BusanAges 50–85 - NCT07540364RecruitingPhase 3
Testing Samelisant for Narcolepsy Daytime Sleepiness
This study tests whether a new medication called samelisant can reduce extreme daytime sleepiness and sudden muscle weakness (cataplexy) in people with narcolepsy. If it works, it could offer a new treatment option for managing this sleep disorder.
Columbia, South CarolinaAges 18 years+ - NCT07538570RecruitingPhase 4
Pain Management After Knee Replacement Surgery
This study tests different pain treatments for patients undergoing total knee replacement surgery. The goal is to find the most effective way to manage pain after this common procedure.
Bellaire, TexasAges 18–80 - NCT07540897RecruitingPhase 3
Testing ALKS 2680 for narcolepsy type 1
This study tests whether a new medication called ALKS 2680 can help people with narcolepsy type 1 stay more awake and alert during the day. Narcolepsy type 1 is a neurological condition where people fall asleep unexpectedly and may experience sudden muscle weakness.
Brandon, FloridaAges 18–70 - NCT07542483RecruitingPhase 3
Lebrikizumab for nummular eczema in adults
This study tests whether lebrikizumab, a new injection, can reduce nummular eczema (coin-shaped eczema patches) in adults whose condition hasn't improved with topical steroid creams. It's designed to help people with moderate-to-severe nummular eczema who need a stronger treatment option.
Freiburg im BreisgauAges 18 years+ - NCT07535099RecruitingPhase 1
Safety study of ICP-538 in healthy volunteers
This trial tests a new drug called ICP-538 in healthy people to see how safe it is and how the body processes it. It is an early-phase study that helps decide if the drug can move to testing in patients with a specific condition.
Beijing, Beijing MunicipalityAges 18–50 - NCT07535034RecruitingPhase 2
Testing Dotinurad for Gout in People Who Can't Take Other Medications
This trial tests a new drug called dotinurad for gout patients whose standard medications either don't work or cause side effects. Dotinurad works differently by helping your body get rid of uric acid (the substance that causes gout attacks), and the study will see if it safely lowers uric acid levels.
Birmingham, AlabamaAges 18–75 - NCT06700044Recruiting
Probiotics for high-risk pregnancy
This study tests whether taking a probiotic supplement during pregnancy can help prevent complications in women at risk for preeclampsia. You would take a daily probiotic or placebo pill from about 20 weeks until delivery.
LundAges 18 years+ - NCT07534241Recruiting
Reishi Mushroom for Fatty Liver Disease
This study tests whether reishi mushroom (a type of fungus) can improve liver health in people with metabolic dysfunction-associated fatty liver disease—a condition where fat builds up in the liver. Researchers want to see if this natural supplement can reduce liver inflammation and improve blood sugar and cholesterol levels.
LahoreAges 35–65 - NCT07536152RecruitingPhase 4
Antihistamine to prevent allergic reactions during heart surgery
This study tests whether giving an antihistamine (a common allergy medication) before heart surgery can prevent allergic-type reactions that sometimes happen during the surgery itself. The trial includes children with certain types of congenital heart disease (heart problems present from birth).
Giza, OctoberAges 1–7 - NCT07539805RecruitingPhase 2
Sertraline Plus Probiotic for Teen Depression
This study tests whether combining sertraline (an antidepressant) with a specific probiotic called Lactobacillus crispatus can safely and effectively treat depression in teenagers. The probiotic may help by improving gut health, which researchers believe could support mental health.
Longgang, Chongqing MunicipalityAges 12–18 - NCT07536568Recruiting
Caffeine to speed recovery after eye surgery in older adults
This study tests whether a small dose of caffeine placed under the tongue helps older adults wake up faster and feel less confused after eye surgery under general anesthesia. Researchers want to see if this simple approach can improve how quickly patients recover and reduce post-surgery agitation.
CairoAges 65 years+ - NCT07540949Recruiting
Lemon Fermented Product for Weight and Metabolism in Adults
This study tests whether a lemon fermented product supplement can help improve metabolism and metabolic health in adults with obesity. Participants will take capsules and have their metabolism and health markers measured over time.
TaoyuanAges 18–65 - NCT07542730RecruitingPhase 4
Diphenhydramine to ease discomfort during early abortion procedure
This study tests whether adding diphenhydramine (a common allergy medicine) to sedation helps patients feel more comfortable during a procedural abortion in the first trimester. Researchers want to see if it improves pain control and overall experience.
Rochester, New YorkAges 18 years+ - NCT07536373RecruitingPhase 3
Colchicine to prevent amputation after leg artery treatment
This study tests whether a medication called colchicine can help prevent amputation in people with severe leg blood flow problems who just had surgery or a catheter procedure to restore blood flow. Colchicine is an anti-inflammatory drug that may help protect the leg tissue after treatment.
Taipei, TaipeiAges 18 years+ - NCT07539623RecruitingPhase 3
Pain relief with suzetrigine after heart or weight-loss surgery
This study tests whether suzetrigine, a new pain medication, can reduce the need for opioids (strong painkillers) after cardiac or bariatric surgery. The goal is to help patients manage pain with fewer opioid-related side effects.
New York, New YorkAges 18–85 - NCT07539298RecruitingPhase 2/Phase 3
Valsartan for Heart-Related Mitral Valve Leaking
This study tests whether a blood pressure medication called valsartan can reduce leaking in the mitral valve (a valve in your heart) caused by an enlarged left chamber. The goal is to see if this medication can improve heart function and reduce symptoms without needing surgery.
Québec, QuebecAges 18–85 - NCT07535047Recruiting
How Placebo and TENS Work Together for Lower Back Pain
This study tests whether the expectation of pain relief (the placebo effect) can make a device called TENS (transcutaneous electrical nerve stimulation) work better for acute lower back pain. TENS uses gentle electrical pulses on your skin to reduce pain.
Giza, Giza GovernorateAges 18–65 - NCT05709249RecruitingPhase 3
Chinese herbal medicine to help prevent colon cancer return
This Phase 3 study tests whether a Chinese herbal “decoction” (called XLJDOD) given after surgery and chemo can lower the chance that colon cancer comes back. It may help people with higher-risk colon cancer (Stage IIIB or IIIC) stay cancer-free longer.
NanjingAges 20–80 - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,904 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.