Clinical trials
Placebo Effect clinical trials
Below are recruiting placebo effect clinical trials, each written for real people, not researchers. We’re tracking 757 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT07625358Recruiting
How Caffeine and Alcohol Affect Your Eyes
This study measures how caffeine and alcohol change the size of your pupils (the dark circles in your eyes). Researchers want to understand how these common substances affect your eye's natural responses, which could help with vision and neurological research.
SingaporeAges 30–50 - NCT06064669Recruiting
Metformin for healthy live birth in women with prediabetes
This study tests if metformin, a drug that helps control blood sugar, can improve the chance of a healthy live birth in women with prediabetes who are doing in vitro fertilization (IVF). It aims to see if treating prediabetes before and during early pregnancy leads to better outcomes.
Jinan, ShandongAges 20–40 - NCT06511908RecruitingPhase 2
Testing a new ketamine-like drug for hard-to-treat depression
This study tests a new experimental drug (2R,6R)-HNK, a chemical related to ketamine, given by IV infusion to see if it can help people with depression that hasn't improved with other treatments. The goal is to find a new option for people who have not found relief from standard antidepressants.
Bethesda, MarylandAges 18–70 - NCT07218445RecruitingPhase 4
Tirzepatide for hot flashes in postmenopausal women with obesity
This study tests whether tirzepatide, a weekly injection, can reduce hot flashes and slow biological aging in postmenopausal women with obesity. It may help if you are experiencing bothersome hot flashes and are willing to follow a diet and exercise plan.
Jacksonville, FloridaAges 46–60 - NCT07671924RecruitingPhase 2
Testing nalbuphine extended-release for chronic cough
This trial tests whether an extended-release medication called nalbuphine can reduce coughing in people with chronic cough that hasn't improved with other treatments. You may be eligible if you've had a persistent cough for at least a year and have already tried treatments for conditions that could cause it.
AjaxAges 18 years+ - NCT03552705RecruitingPhase 2
Tranexamic acid to reduce knee inflammation after ACL injury
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Stanford, CaliforniaAges 18–30 - NCT07162116RecruitingPhase 1
Effect of XY0206 on heart rhythm in healthy Chinese volunteers
This trial tests whether a new drug called XY0206 affects the heart's electrical activity (QTc interval). Healthy participants take either XY0206, a placebo, or a control drug to compare effects. It helps ensure the drug is safe for the heart before testing in patients.
Zibo, ShandongAges 18–45 - NCT06757517RecruitingPhase 2
Nasal spray oxytocin for benzodiazepine withdrawal
This trial tests if a nasal spray containing the hormone oxytocin can help reduce withdrawal symptoms when stopping benzodiazepine (benzos) medications like Valium. You might be eligible if you have been taking a moderate to high daily dose of a benzodiazepine and are entering a hospital program to taper off.
Trondheim, TrøndelagAges 18–65 - NCT07386249Recruiting
Wheat lipid cream for vaginal dryness in postmenopausal women
This trial tests a cream made from wheat polar lipids to see if it helps with vaginal dryness after menopause. It may offer a non-hormonal option for women with moderate to severe discomfort.
Louvain-la-Neuve, BelgiumAges 45–65 - NCT06934473Recruiting
How a gut hormone affects blood pressure after eating in healthy adults
This study looks at how a natural gut hormone called GIP affects blood pressure after a meal. It may help find new ways to treat blood pressure problems after eating.
Copenhagen, HellerupAges 18–40 - NCT07006636Recruiting
Watermelon for heart health in postmenopausal women
This study tests whether eating watermelon can improve heart health and blood pressure in postmenopausal women with slightly elevated blood pressure. It lasts about 4 weeks and involves eating watermelon as part of your usual diet.
Los Angeles, CaliforniaAges Any age - NCT06193577Recruiting
White kidney bean extract for weight and metabolism
This trial tests whether a dry extract from white kidney beans (Phaseolus vulgaris) can help men with overweight or mild obesity lose weight and improve metabolic health. Participants will follow a diet and take the extract or a placebo for a few weeks.
Catania, CataniaAges 18–60 - NCT06916208Recruiting
Capsinoid supplement study for obese teens
This study tests whether a supplement called capsinoid can help activate brown fat in teenagers with obesity. Brown fat is a type of body fat that burns calories, so this could be a new way to help with weight management.
Palavas-les-FlotsAges 11–18 - NCT07167342RecruitingPhase 4
Can a probiotic prevent polyp regrowth after colonoscopy?
This trial tests whether taking a probiotic called Clostridium Butyricum after colon polyp removal can lower the chance of polyps coming back. It is looking for people who had adenomas removed and are not already taking certain supplements or antibiotics.
Qingdao, ShandongAges 18–75 - NCT04320199Recruiting
Fermented beetle powder for alcohol-related liver problems
This trial tests whether a fermented powder made from a specific beetle can improve or protect the liver after alcohol-related liver injury. It’s looking for people with certain liver blood test levels, and it excludes several conditions and recent herbal or liver-affecting treatments.
Pusan, Ami-dongAges 19 years+ - NCT04447911RecruitingPhase 4
Empagliflozin for chronic low blood sodium in certain fluid states
This trial studies whether empagliflozin, a blood-sugar–related medicine, can safely improve chronic low blood sodium when you are not too “dry” or have an imbalanced fluid state. It may help stabilize sodium levels and related health symptoms, but you must meet specific blood and organ-function criteria.
WürzburgAges 18 years+ - NCT05005793RecruitingPhase 4
Alkali treatment to improve kidney graft blood vessel function
This trial tests whether adding an “alkali” treatment (to raise low blood bicarbonate) can improve blood vessel and kidney graft function in people whose kidney transplant is about 1 year old. It may help if you have lower-than-normal bicarbonate levels while on stable transplant and blood pressure medicines.
Aurora, ColoradoAges 18–80 - NCT05112328Recruiting
Pancreatic enzyme added to feeding for ICU adults
This study tests whether adding pancreatic digestive enzymes to tube feeding can improve digestion and outcomes in critically ill adults who have higher risk of not producing enough digestive enzymes. If you qualify, you may receive the enzyme supplement or a comparison treatment while you’re in the ICU.
Seoul, Jongno-guAges 18 years+ - NCT05211895RecruitingPhase 3
Durvalumab plus domvanalimab after chemoradiation for stage 3 lung cancer
This trial studies whether adding durvalumab and domvanalimab after standard chemoradiation can keep unresectable stage 3 lung cancer from coming back or getting worse. It targets tumors with specific lab test results (including PD-L1 and gene markers).
Chandler, ArizonaAges 18 years+ - NCT05428228Recruiting
Hydration drink study in healthy adults
This study tests two new hydration drink formulas to see how well they rehydrate healthy adults. It’s mainly about measuring how your body responds after drinking the study products during visits.
Memphis, TennesseeAges 18–35 - NCT05818787Recruiting
Vestibular training to improve balance and dizziness thresholds
This trial tests whether a structured “vestibular perceptual learning” program can improve balance and your body’s balance signals. It may help people who have balance or dizziness challenges by measuring changes after training.
Columbus, OhioAges 65–89 - NCT05823727Recruiting
Collagen supplement study before and after knee replacement
This study tests whether taking collagen peptides can improve how knee tissues heal and remodel after total knee arthroplasty (knee replacement). It also looks at functional recovery and wound healing, especially during the physical therapy period in Little Rock.
Little Rock, ArkansasAges 50–75 - NCT06078683Recruiting
Ketone drink for exercise and heart health in type 2 diabetes
This study tests whether a special ketone drink can improve exercise ability and heart function in people with type 2 diabetes. Participants will have two treadmill exercise tests and heart MRI scans to see how the drink affects their performance and cardiac efficiency.
Columbus, OhioAges 18–80
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Common questions
- Are there clinical trials for placebo effect?
- Yes. Clin2 currently lists 757 recruiting placebo effect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo effect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo effect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.