Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,158 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05110144RecruitingPhase 2
Testing two doses of two nerve pain medicines for chronic cough
This Phase 2 study tests whether two doses of duloxetine and amitriptyline can reduce symptoms in people with chronic cough that hasn’t responded to usual care. You may join to see if these medicines lessen cough severity over an 8-week blinded treatment period.
Rochester, MinnesotaAges 18–75 - NCT05016219Recruiting
Light therapy to improve sleep and thinking in early Alzheimer’s
This trial studies rhythmic light therapy to help people with early Alzheimer’s or mild memory problems, especially when sleep is getting worse. If you fit the sleep and vision/medical safety requirements, the study may see whether the therapy improves sleep and thinking-related symptoms.
Menands, New YorkAges 55 years+ - NCT05028829RecruitingPhase 2
Atorvastatin to lower liver cancer risk in people with liver scarring
This trial tests whether atorvastatin (a cholesterol medicine) can lower the chance of liver cancer (HCC) in people with advanced liver scarring or cirrhosis. Participants are compared to placebo (inactive pill) while researchers track safety and cancer risk.
Boston, MassachusettsAges 18 years+ - NCT04998188Recruiting
Hydrolyzed collagen for one knee with osteoarthritis
This trial tests whether a hydrolyzed collagen drink or supplement can reduce knee pain and symptoms compared with a placebo (inactive treatment) in people with osteoarthritis. It may help if you’ve tried standard non-surgical treatments and still have ongoing knee trouble.
BolognaAges 18–75 - NCT04858334RecruitingPhase 2
Olaparib after pancreatic cancer surgery for BRCA or PALB2 mutations
This trial studies whether olaparib (a targeted cancer medicine) can help prevent pancreatic cancer from coming back after surgery in people with BRCA1, BRCA2, or PALB2 mutations. You would get olaparib or a placebo (inactive pill) and be closely followed to see if recurrence is reduced.
Anchorage, AlaskaAges 18 years+ - NCT04910685RecruitingPhase 2/Phase 3
BLU-263 for indolent mast cell disease with symptom control
This trial tests BLU-263, a study medicine, against placebo (inactive treatment) to see if it improves symptoms in people with indolent systemic mastocytosis. It also checks safety and how well the dose is tolerated before and during treatment.
Birmingham, AlabamaAges 18 years+ - NCT04853342RecruitingPhase 3
Furmonertinib after lung tumor removal for EGFR-mutated lung cancer
This trial tests whether furmonertinib, an oral targeted medicine, can improve outcomes after your lung tumor has been completely removed. It also checks for side effects and compares results against placebo in people with specific EGFR gene mutations.
Suzhou, JiangsuAges 18–75 - NCT04218409RecruitingEarly Phase 1
Tests a spray to reduce opioid use and pain
This early trial studies whether Syntocinon can lower pain and help reduce how much opioids people use. It checks safety and the best dose by giving participants the study drug under close medical monitoring.
Gainesville, FloridaAges 21–45 - NCT04374799RecruitingPhase 3
Heparin vs placebo during cardiac catheterization
This trial tests whether giving heparin (a blood thinner) during a specific type of heart procedure is safer and works better than not giving it. It focuses on patients where the blood supply in the hand’s artery connection is functioning properly.
Hamilton, OntarioAges 18 years+ - NCT04302870RecruitingPhase 2/Phase 3
Test medicines for motor neurone disease using adaptive trial design
This study tests treatments for motor neurone disease (MND) and assigns people to different treatment arms in an adaptive way. It may help doctors find out which medicine works best and for whom.
Portadown, County ArmaghAges 18 years+ - NCT04227314RecruitingPhase 3
Apremilast vs placebo for severe recurrent mouth ulcers
This Phase 3 trial tests whether apremilast can reduce severe, recurring mouth ulcers compared with an inactive placebo. It aims to improve ulcer frequency and pain while carefully checking safety.
AmiensAges 18 years+ - NCT04065971RecruitingPhase 4
Test drug for frequent cold sores in the mouth
This trial tests whether 2LHERP® can reduce or manage frequent herpes infections around the mouth. It compares the study drug to a placebo (inactive treatment) in people who get many episodes each year.
BeerzelAges 16–80 - NCT04059172RecruitingEarly Phase 1
Ibuprofen plus acetaminophen for braces pain
This early study compares braces pain relief using: ibuprofen alone, ibuprofen plus acetaminophen together, or placebo (no active pain medicine). It may help find which approach works best and is safest for people starting orthodontic treatment.
Aurora, ColoradoAges 12–80 - NCT04041713RecruitingPhase 2
Antioxidant drink trial for children with Rett syndrome
This Phase 2 trial studies whether an antioxidant “cocktail” helps children and teens with Rett syndrome compared with a placebo (inactive drink). If you join, you’ll get study assessments and blood tests to see if the treatment is safe and helpful.
Toronto, OntarioAges 2–21 - NCT03977753RecruitingPhase 4
Study medicine to treat common, plantar, or flat warts
This trial tests two versions of an at-home medicine to see how well they clear warts. Participants are randomly assigned to the study medicine or a placebo (inactive treatment) so researchers can compare results fairly.
BougeAges 3 years+ - NCT03587701RecruitingPhase 2
Anakinra for steroid-resistant inner ear inflammation
This trial tests an anti-inflammatory drug (anakinra) in people whose inner-ear hearing problems have not improved with steroid treatment. It aims to reduce worsening hearing caused by autoimmune inner ear disease or difficult-to-control Meniere’s disease.
New Hyde Park, New YorkAges 18–75 - NCT03684278RecruitingPhase 2
Infliximab for new acute pancreatitis patients in the first 36 hours
This trial tests infliximab (an anti-inflammatory medicine) versus placebo to see if it improves outcomes in adults with newly diagnosed acute pancreatitis. It is designed for treatment to start within 36 hours of hospital admission.
Aberdeen, AberdeenshireAges 18–85 - NCT03234296Enrolling by invitation
Antibiotics versus placebo for uncomplicated appendicitis
This trial tests whether taking antibiotics alone can treat acute uncomplicated appendicitis, compared with a placebo. If antibiotics work, it may help some people avoid surgery or reduce treatment intensity.
TurkuAges 18–60 - NCT03255408RecruitingPhase 1/Phase 2
Sleep study testing breathing and blood flow in healthy adults
This study looks at how your brain blood flow and breathing change during sleep under normal oxygen and reduced oxygen. It will only include healthy adults so researchers can learn what “intermittent hypoxia” does to the body in people without medical problems.
Calgary, AlbertaAges 18–45 - NCT03013998RecruitingPhase 2/Phase 3
Personalized treatment study for acute myeloid leukemia
This study matches people with acute myeloid leukemia (AML) to treatments based on their specific genetic markers. It aims to find the most effective therapy with fewer side effects compared to standard care.
Phoenix, ArizonaAges 18 years+ - NCT02947750RecruitingPhase 2
Exercise study in people with kidney disease
This Phase 2 study tests how engaging in supervised exercise affects the body’s blood-vessel responses in people with chronic kidney disease (CKD) who don’t exercise regularly. It may help researchers understand whether exercise could be beneficial for CKD-related health changes.
Atlanta, GeorgiaAges 18–75 - NCT01631617RecruitingPhase 2
Atopic dermatitis treatments and how they affect skin
This Phase 2 study tests different treatments for atopic dermatitis (eczema) by looking at changes in skin health. It may help people find safer, more effective ways to control moderate to severe eczema and related skin infections.
Bethesda, MarylandAges 2–50 - NCT07881640Recruiting
Sound therapy to reduce stress during wisdom tooth removal
This study tests whether listening to special sounds called binaural beats can help lower stress and improve recovery after wisdom tooth surgery. Participants listen to these sounds during their procedure, and researchers check stress levels and recovery afterward.
RizeAges 18–45 - NCT07283770RecruitingPhase 1
Study of VX-581 in healthy people and in people with cystic fibrosis
This study tests an experimental drug called VX-581 in two groups: healthy volunteers to check safety, and people with cystic fibrosis to see how the drug affects them. It may help find a new treatment option for cystic fibrosis.
Overland Park, KansasAges 18–55
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,158 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.