Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 561 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07591233Recruiting
Pain Relief Injection During Laparoscopic Surgery
This trial tests whether injecting a numbing medication mixed with a steroid into the surgical area before making cuts can reduce pain after common laparoscopic procedures like gallbladder removal or hernia repair. The goal is to help patients recover with less pain and fewer pain medications.
Beijing, Beijing MunicipalityAges 18–64 - NCT07599254RecruitingPhase 4
Pain Relief After Root Canal Retreatment
This study tests two different ways of cleaning and treating a tooth that had a root canal treatment before. Researchers want to see which method causes less pain after the procedure.
KayseriAges 18–60 - NCT07612761Recruiting
Pain Relief Methods for Hip Fracture Surgery
This trial compares two different nerve-blocking techniques to help manage pain after hip fracture surgery. Both methods numb the area around your hip to reduce pain and may help you recover better.
Istanbul, IstanbulAges 18 years+ - NCT07619651Recruiting
Pain relief methods after hypospadias repair in young boys
This trial compares two different numbing techniques to help manage pain after hypospadias surgery (a procedure to correct the urinary opening in boys). The goal is to find which method works better and is safer for young children.
KayseriAges 6 months–7 years - NCT07630337Recruiting
Cryotherapy to reduce pain medication after knee replacement
This study tests whether applying cold therapy (cryotherapy) after knee replacement surgery helps patients need fewer opioid pain medications than standard care alone. If cryotherapy works, it could help you manage pain more safely after surgery.
Buenos Aires, Buenos AiresAges 18 years+ - NCT07650877Recruiting
Pain relief blocks for minimally invasive chest surgery
This study compares two different types of nerve blocks (numbing injections near the ribs) to see which one works better for pain relief after minimally invasive chest surgery. Both techniques are standard care options, and the trial will help doctors understand which one provides the best pain control.
Çankaya, AnkaraAges 18–75 - NCT07653490Recruiting
Two anesthesia methods for gallbladder surgery
This study tests whether a numbing injection in the back (erector spinae plane block) helps reduce anesthesia needs during gallbladder surgery. It compares two anesthesia methods to see which works better for pain control and recovery.
IstanbulAges 18–65 - NCT07655323Recruiting
RISS vs. ESP Block for Gallbladder Surgery Pain
This study compares two types of nerve blocks (RISS and ESP) to manage pain after gallbladder removal surgery. It aims to find which block provides better pain relief.
Bursa, NilüferAges 18–75 - NCT07655336Recruiting
Nerve block comparisons for lung-sparing chest surgery
This trial compares two types of nerve blocks to manage pain during and after a type of lung surgery that removes only part of the lung. It aims to find which block provides better pain relief and recovery.
Bursa, NilüferAges 18–75 - NCT07659990Recruiting
Comparing two nerve blocks for mastectomy pain relief
This study compares two types of nerve blocks given before a mastectomy (breast removal surgery) to see which one provides better pain relief. If you are having a mastectomy on one side with lymph node removal, you may be able to join.
Bursa, NilüferAges 18–75 - NCT07626684Enrolling by invitation
Ice Pack After Minimally Invasive Hysterectomy Surgery
This study tests whether applying ice packs to the abdomen after a minimally invasive hysterectomy (removal of the uterus through the vagina) helps reduce pain and speed recovery. You would be randomly assigned to either receive ice pack treatment or standard care.
MuğlaAges 48–70 - NCT07287657Enrolling by invitation
Electrical acupoint stimulation after chest surgery
This trial tests a gentle, non-needle therapy that stimulates acupoints with mild electrical current to help you recover better after chest surgery. It may reduce pain and speed healing.
Taipei, HualienAges 15 years+ - NCT07219888Enrolling by invitationPhase 4
Comparing suzetrigine and oxycodone for knee replacement pain
This study compares a new pain medicine called suzetrigine with a commonly used opioid, oxycodone, for pain after a knee replacement. The goal is to see which works better and has fewer side effects.
Louisville, KentuckyAges 21–89 - NCT06997016Enrolling by invitationPhase 4
Recovery program for living donor kidney transplant
This trial tests a special recovery program (ERAS) for people who get a kidney from a living donor. The program aims to help you heal faster and feel better after surgery.
Fort Worth, TexasAges 18 years+ - NCT06989866Enrolling by invitationPhase 3
Testing if numbing injections reduce pain pill use after nose surgery
This trial tests whether a numbing injection (regional anesthesia) during nose surgery can reduce the need for strong pain pills afterward. It's for people having their first nose surgery at specific military hospitals.
Portsmouth, VirginiaAges 18 years+ - NCT06957990Enrolling by invitation
Music therapy during hernia surgery to reduce pain medication
This study tests if listening to music therapy before and during hernia surgery can lower the need for strong painkillers (narcotics). It may help you manage pain with less medication.
Cincinnati, OhioAges 18 years+ - NCT06926322Enrolling by invitation
Treating dead baby molars with special medicines
This study tests different medicines to treat dead (necrotic) baby molars in children. The goal is to safely clean the infection and save the tooth so it can stay until it falls out naturally.
CairoAges 4–8 - NCT06800846Enrolling by invitationPhase 4
Pain relief after knee replacement: injection methods compared
This study compares two ways to give pain medicine during knee replacement surgery: one is injected into the bone, the other around the joint. Researchers want to see which works better and may help you recover with less pain.
Khlong Luang, Changwat Pathum ThaniAges 50–80 - NCT06636331Enrolling by invitation
Pain relief after hip surgery: comparing two numbing methods
This trial compares two ways to numb the hip and thigh area after a specific type of hip surgery (cephalomedullary nailing). One method uses a continuous nerve block above the hip bone, and the other uses a continuous epidural. The goal is to find which offers better pain control.
Denpasar, BaliAges 18–65 - NCT06619340Enrolling by invitationPhase 4
Exparrel block for knee replacement pain relief
This trial tests a special numbing injection called an EXPAREL IPSA block to see how well it controls pain after knee replacement surgery. It is for people with knee arthritis who are having their first knee replacement under spinal anesthesia.
Germantown, TennesseeAges 18 years+ - NCT06601413Enrolling by invitation
Nerve block for pain after laparoscopic hysterectomy
This study tests a special type of nerve block (called M-TAPA) to manage pain after a laparoscopic hysterectomy. It aims to see if this block provides better pain relief than standard care.
AnkaraAges 18–65 - NCT06575010Enrolling by invitationPhase 4
Comparing pain relief methods for rotator cuff repair surgery
This trial tests two different pain relief methods for people having rotator cuff repair surgery. The goal is to see which one works better for managing pain after surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06562634Enrolling by invitation
Ultrasound-guided nerve block for knee surgery pain relief
This study tests a nerve block (erector spinae plane block) to see if it reduces pain after open knee surgery. It aims to find a better way to manage pain with fewer side effects.
CairoAges 18–65 - NCT06402149Enrolling by invitation
Comparing two ways to numb the arm for surgery
This trial tests two different methods for numbing the arm (infraclavicular block) before upper extremity surgery. It aims to find out which approach works better to block pain.
AnkaraAges 18 years+
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 561 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.