Clinical trials
Posttraumatic Stress Disorder (PTSD) clinical trials
Below are recruiting posttraumatic stress disorder (ptsd) clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07079839Recruiting
Anxiety and stress study for adults with PTSD
This study looks at how the brain processes anxiety and stress in people with PTSD and healthy adults. It uses brain scans and mild electrical stimulation to understand these responses better.
Houston, TexasAges 18–50 - NCT07105345Recruiting
Cognitive processing therapy trial for PTSD
This trial tests a type of talk therapy called Cognitive Processing Therapy (CPT) to see if it helps people with post-traumatic stress disorder (PTSD). It aims to reduce PTSD symptoms and improve your daily life.
New Taipei City, Banqiao DistrictAges 20–65 - NCT07106593Recruiting
Talk therapy for PTSD and tinnitus after concussion
This study tests a type of talk therapy for people with both PTSD and chronic tinnitus that started after a mild head injury. The therapy aims to help reduce symptoms of both conditions together.
San Antonio, TexasAges 18 years+ - NCT07146633Recruiting
Testing an EMDR app for PTSD and substance use
This study tests an app that uses EMDR therapy to help people with both PTSD and substance use problems. EMDR is a type of therapy that uses eye movements or taps to help process traumatic memories. You would use the app at home and avoid starting other new therapies during the study.
Toronto, OntarioAges 18 years+ - NCT07176273Recruiting
Personalized PTSD Treatment for Veterans
This trial helps veterans with PTSD choose between two proven talk therapies—Prolonged Exposure (PE) or Cognitive Processing Therapy (CPT)—and uses a smartphone app to support their treatment. The goal is to see which approach works best for each person.
Augusta, GeorgiaAges 18 years+ - NCT07220681Recruiting
Integrated Care for PTSD
This study tests whether combining different treatments can help Veterans with PTSD. It focuses on those who can receive Cognitive Processing Therapy (CPT) at a VA site.
Little Rock, ArkansasAges 18 years+ - NCT07238192Recruiting
Testing a therapy to reduce suicide risk in veterans with PTSD
This trial is testing whether a therapy called Cognitive Processing Therapy (CPT), given in an intensive format, can reduce suicide risk in veterans and active duty service members with PTSD. It aims to see if this approach is more effective than standard care at preventing suicidal thoughts and behaviors.
Fort Hood, TexasAges 18 years+ - NCT07317206RecruitingPhase 2
Ayahuasca vs Esketamine for PTSD
This trial tests two treatments—ayahuasca and esketamine—to see if they can help people with PTSD. It's for people who have PTSD and no other health problems.
Ribeirão Preto, São PauloAges 18–65 - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT02695953Enrolling by invitation
Study brain changes after trauma-focused therapy for PTSD
This study looks at how the brain works and how it changes after Cognitive Processing Therapy (CPT) for people with PTSD. You might help researchers learn why this therapy helps and who may benefit most.
Belmont, MassachusettsAges 18–55 - NCT02757339Enrolling by invitation
Study of brain differences in dissociation after abuse
This study looks at brain activity and biology in women who have PTSD or dissociative identity disorder (DID) with a history of childhood abuse or neglect. It may help researchers understand what causes “traumatic dissociation” and how it develops.
Belmont, MassachusettsAges 18–89 - NCT07630428Enrolling by invitation
Support programs after sexual assault medical exam
This study tests two support programs—STAR and TextSTAR—designed to help people after a sexual assault medical exam. The goal is to see which approach better supports your recovery and connects you with resources.
Louisville, KentuckyAges 18 years+ - NCT07565311Recruiting
Intensive Two-Week Outpatient Treatment for PTSD
This study tests a concentrated two-week outpatient program designed to help people with post-traumatic stress disorder (PTSD) recover from trauma. The goal is to see if intensive treatment delivered over a short period can effectively reduce PTSD symptoms.
OsloAges 18–65 - NCT07604753Recruiting
Comparing two mental health screening questionnaires
This study compares two different questionnaires that doctors use to diagnose mental health conditions. Researchers want to check if a newer, shorter questionnaire works just as well as the longer standard one.
Hong KongAges 18 years+ - NCT06954025Enrolling by invitationPhase 2
MDMA therapy for PTSD inpatients
This trial tests whether high-dose MDMA, given during intensive inpatient therapy, can help people with PTSD that hasn't improved with other treatments. It takes place at a specialized trauma center and involves several therapy sessions with the drug.
OegstgeestAges 18 years+ - NCT06746818Enrolling by invitation
Building resilience in older adults with PTSD
This trial tests if a HeartMath-based program can help older adults improve resilience, reduce posttraumatic stress, and boost spiritual and psychosocial well-being. It may be an option if you are 60 or older and have experienced trauma.
Al MansurahAges 60 years+ - NCT05427500Enrolling by invitationPhase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms
This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.
Ottawa, OntarioAges 18–69 - NCT06047691Recruiting
Couples therapy for PTSD in military couples
This study tests whether intensive couples therapy helps military couples dealing with PTSD, compared to a relationship education class. If you are a service member or veteran with PTSD and your partner is willing to join, this trial might offer a way to improve your relationship and PTSD symptoms together.
San Antonio, TexasAges 18 years+ - NCT05233111Enrolling by invitation
Exposure therapy to reduce PTSD after spinal cord injury
This trial compares a specific type of talk therapy (brief prolonged exposure) versus standard care to reduce post-traumatic stress symptoms after a spinal cord injury. If you qualify, you may get extra support targeted at PTSD symptoms during inpatient rehab.
Dallas, TexasAges 18 years+ - NCT07462312Recruiting
Wearable device training for PTSD
This trial tests a training program that uses a wearable device to help you control your body's stress responses. It's designed for people with PTSD who are eligible for military rehabilitation services.
JerusalemAges 18–50 - NCT05457985Recruiting
Adaptive app coaching for PTSD in community health clinics
This study tests a flexible (adaptive) approach using a mobile app to help improve treatment outcomes for posttraumatic stress disorder (PTSD) for people getting care at participating community health clinics. It may help you get more tailored support between visits.
Baldwin, MichiganAges 18 years+ - NCT05267665Recruiting
Family-involved PTSD therapy coaching for Veterans
This study tests a brief way to include a Veteran’s family member to improve PTSD treatment results and help people stay engaged in care. It’s for Veterans who are just starting evidence-based PTSD therapy and have a closely involved family member who can participate too.
Boston, MassachusettsAges 18 years+ - NCT04529031Recruiting
Study of reminder-based positive thinking for teens with PTSD
This study looks at whether a “reminder-focused positive thinking” approach can help teens with PTSD. It may benefit you by testing how certain cues and supportive thoughts affect PTSD symptoms and related wellbeing.
Los Angeles, CaliforniaAges 11–15 - NCT05624931Recruiting
Helping pregnant women stay on PrEP after starting it
This study tries to reduce the psychological barriers that make it hard for pregnant or postpartum women to keep taking PrEP. It may help by offering support tailored to stress, trauma symptoms, or depression—especially soon after PrEP is started.
Boston, MassachusettsAges 15 years+
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Common questions
- Are there clinical trials for posttraumatic stress disorder (ptsd)?
- Yes. Clin2 currently lists 90 recruiting posttraumatic stress disorder (ptsd) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a posttraumatic stress disorder (ptsd) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a posttraumatic stress disorder (ptsd) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.