Clinical trials
Prediabetes clinical trials
Below are recruiting prediabetes clinical trials, each written for real people, not researchers. We’re tracking 140 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06690788Recruiting
Couples program to prevent type 2 diabetes (PreventT2 Together)
This research study looks at whether a lifestyle program designed for couples can help prevent type 2 diabetes. Both partners take part together, and the program is based on the National Diabetes Prevention Program.
Salt Lake City, UtahAges 18 years+ - NCT06694155Recruiting
Whey protein and blood sugar study for pre-diabetes and diabetes
This study tests whether drinking whey protein can help control blood sugar in people with pre-diabetes or mild diabetes. If you qualify, you'll wear a continuous glucose monitor and keep a food journal for two weeks.
Little Rock, ArkansasAges 50–70 - NCT04666636RecruitingPhase 2
Test a drug idea to activate fat that burns energy
This Phase 2 study tests whether a medication approach can activate “beige” fat, which may help the body burn more energy. It mainly looks for people with higher body weight and prediabetes who are not on diabetes medicines.
Lexington, KentuckyAges 35–65 - NCT07688278Recruiting
Diabetes screening for people with advanced gum disease
This trial tests whether checking blood sugar (HbA1c) at the dentist can find undiagnosed diabetes. It is for adults with advanced periodontitis (severe gum disease) who have not already been told they have diabetes.
SkåneAges 18 years+ - NCT07403604RecruitingPhase 1
Lowering Insulin to Reduce Fat Buildup in the Liver
This study tests if lowering insulin levels can reduce fat buildup in the liver for people with a fatty liver condition called MASLD. It's looking for adults who are overweight and have early signs of insulin resistance but not diabetes.
New York, New YorkAges 18–65 - NCT06752772Recruiting
Wearable health coaching for blood pressure and weight
This study tests a digital health coaching program that uses a smartwatch and smartphone to help people manage conditions like high blood pressure, pre-diabetes, or weight. It aims to see if wearable technology can improve your health with personalized coaching.
SingaporeAges 21–75 - NCT06817252Recruiting
Mediterranean diet with potatoes for pre-diabetes
This study tests whether adding potatoes to a Mediterranean diet can improve heart health and blood sugar control in adults with pre-diabetes. You'll follow a specific meal plan and be monitored over time.
Las Vegas, NevadaAges 45–80 - NCT06893913Recruiting
Fasting plus exercise for dry eyes in psoriasis
This study tests whether adding a simple exercise (pyramidal exercise) to intermittent fasting can help reduce dry eyes in people who have psoriasis, prediabetes, and mild obesity. It aims to see if lifestyle changes can improve eye moisture.
Giza, DokkiAges 45–55 - NCT06921902Recruiting
Study of blood sugar patterns in people with and without prediabetes
This study monitors blood sugar levels and patterns in people with and without prediabetes. It uses a continuous glucose monitor to see how blood sugar varies during daily life, and helps researchers understand early signs of blood sugar problems. You may be eligible if you do not have diabetes and are not on special diets or certain medications.
Bend, OregonAges 18 years+ - NCT06963736Recruiting
Reducing health risks from too much evening screen time
This study tests simple strategies to help people who spend a lot of time on screens at night and eat after 8pm. It aims to reduce health risks like high blood pressure, belly fat, and blood sugar issues.
Tempe, ArizonaAges 26 years+ - NCT06986161Recruiting
How eating mangoes at different times affects blood sugar
This study tests whether eating mangoes at breakfast or as a snack helps control blood sugar better. It's for people with prediabetes who want to see if fruit timing can improve their health.
Chicago, IllinoisAges 20–60 - NCT06989164Recruiting
How Your Body Responds to Different Foods After Eating
This study looks at how different foods affect your body after eating, especially your blood sugar and other metabolic responses. It may help find personalized ways to eat better for your health.
Stanford, CaliforniaAges 18–80 - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT07210684Recruiting
Dihydroberberine for blood sugar, appetite, and mood in prediabetes
This study tests a supplement called dihydroberberine (DHB) to see if it helps improve blood sugar control, appetite, and mood in adults with prediabetes. You will wear a small sensor to track your blood sugar and use a phone app to record what you eat.
Addison, IllinoisAges 35–65 - NCT07225218Recruiting
Diabetes prevention program for UCLA students
This study tests a wellness program for UCLA undergraduates who are at risk for developing diabetes. It aims to help students prevent diabetes through support and education.
Los Angeles, CaliforniaAges 17–25 - NCT07243821Recruiting
Metabolic syndrome and prediabetes study
This study looks at people with metabolic syndrome or prediabetes to understand how these conditions affect health. You may qualify if you have at least three signs of metabolic syndrome or if your blood sugar levels are higher than normal.
Taipei, Zhongzheng DistAges 18 years+ - NCT07254572RecruitingPhase 4
Comparing diabetes drugs for heart health in prediabetes
This trial tests whether certain diabetes medications can help prevent worsening of heart disease in people who have prediabetes (higher than normal blood sugar, but not yet diabetes). It may be a good fit if you have known coronary artery disease and prediabetes.
WarsawAges 18–80 - NCT07624500Recruiting
How Different Foods Affect Your Metabolism and Blood Sugar
This study tests how specific foods impact your body's ability to manage blood sugar and fat levels. You'll eat meals provided by the research team for about 12 weeks to help researchers understand which foods work best for people with high triglycerides (a type of blood fat) and insulin resistance (difficulty managing blood sugar).
Chicago, IllinoisAges 40–70 - NCT07371546Recruiting
Continuous Glucose Monitoring in Prediabetes
This study uses a continuous glucose monitor (a small sensor placed on your arm) to track your blood sugar levels over time. It aims to help people with prediabetes better understand their glucose patterns.
SingaporeAges 21–69 - NCT07372729Recruiting
Smartwatch program for heart health in overweight adults
This trial tests if a smartwatch app can help people who are overweight and have slightly high blood pressure, sugar, or cholesterol improve their heart health. If you qualify, you'll use a smartwatch to track your activity and get coaching.
Beijing, Beijing MunicipalityAges 18 years+ - NCT02915198RecruitingPhase 4
Metformin for prediabetes to reduce heart and blood-vessel events
This trial tests whether taking metformin in people with prediabetes can lower the chance of future heart attack, stroke, or other blood-vessel problems. You may be a good fit if you have prediabetes plus existing cardiovascular disease or significant blood-vessel disease.
Phoenix, ArizonaAges 18 years+ - NCT06118931Recruiting
Time-Restricted Eating for Blood Sugar Control
This study tests whether eating only during a specific daily window helps control blood sugar in people with or at risk for type 2 diabetes. You'll follow a set eating schedule and use a phone app to track your meals.
Toronto, OntarioAges 40 years+ - NCT06115265Recruiting
Ketogenic diet study for prediabetes and weight loss
This trial tests whether a ketogenic diet can help people with prediabetes or high blood sugar improve their health and lose weight. You eat very low-carb, high-fat foods to see if it lowers your blood sugar and reduces your risk of developing diabetes.
Albuquerque, New MexicoAges 18 years+ - NCT07599072Recruiting
Blood Sugar Monitoring Study for Prediabetes
This study tracks how blood sugar levels change in people with prediabetes (higher-than-normal blood sugar but not yet diabetes). Researchers will use a small sensor to monitor your blood sugar and help understand what affects it, which could help prevent or delay type 2 diabetes.
KyivAges 18 years+
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Common questions
- Are there clinical trials for prediabetes?
- Yes. Clin2 currently lists 140 recruiting prediabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.