Clinical trials
Prediabetes clinical trials
Below are recruiting prediabetes clinical trials, each written for real people, not researchers. We’re tracking 136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06988462Recruiting
Bottarga supplement for metabolic health
This study tests a supplement called bottarga, made from fish eggs, to see if it improves cholesterol, blood sugar, or weight in people with metabolic problems like high cholesterol or prediabetes. It is a small pilot study for Massachusetts residents.
Sommerville, MassachusettsAges 18–60 - NCT06958640Enrolling by invitation
Da Qing offspring health study
This study looks at the health of children, grandchildren, and great-grandchildren of people who took part in a diabetes prevention study in Daqing, China. It aims to understand how their family history affects their health over time.
Beijing, Beijing MunicipalityAges Any age - NCT06921902Recruiting
Study of blood sugar patterns in people with and without prediabetes
This study monitors blood sugar levels and patterns in people with and without prediabetes. It uses a continuous glucose monitor to see how blood sugar varies during daily life, and helps researchers understand early signs of blood sugar problems. You may be eligible if you do not have diabetes and are not on special diets or certain medications.
Bend, OregonAges 18 years+ - NCT06817252Recruiting
Mediterranean diet with potatoes for pre-diabetes
This study tests whether adding potatoes to a Mediterranean diet can improve heart health and blood sugar control in adults with pre-diabetes. You'll follow a specific meal plan and be monitored over time.
Las Vegas, NevadaAges 45–80 - NCT06804187Enrolling by invitation
Sweet taste and type 2 diabetes study
This study looks at how sweet taste is sensed in people with type 2 diabetes, prediabetes, or no diabetes. It involves taste tests and possibly brain scans (MRI) to help understand why people with diabetes may perceive sweetness differently.
Nottingham, East MidlandsAges 18–60 - NCT06752772Recruiting
Wearable health coaching for blood pressure and weight
This study tests a digital health coaching program that uses a smartwatch and smartphone to help people manage conditions like high blood pressure, pre-diabetes, or weight. It aims to see if wearable technology can improve your health with personalized coaching.
SingaporeAges 21–75 - NCT06694155Recruiting
Whey protein and blood sugar study for pre-diabetes and diabetes
This study tests whether drinking whey protein can help control blood sugar in people with pre-diabetes or mild diabetes. If you qualify, you'll wear a continuous glucose monitor and keep a food journal for two weeks.
Little Rock, ArkansasAges 50–70 - NCT06580964Recruiting
Heat and exercise therapy for aging adults with prediabetes
This study tests whether combining exercise with heat therapy can help older adults with prediabetes improve their health. It may offer a new way to manage blood sugar without medication.
Lubbock, TexasAges 50 years+ - NCT06507722Recruiting
Night Owl Metabolism Study
This study from Johns Hopkins looks at how your body's metabolism works when you're an overweight teen or young adult who sleeps enough. It aims to learn more about your 'night owl' internal clock and how it affects your health.
Baltimore, MarylandAges 18–23 - NCT06482944Recruiting
Whole-food diet program for families to prevent type 2 diabetes
This 12-week program helps parents with prediabetes and their children eat healthier whole foods based on U.S. dietary guidelines. The goal is to see if the program can lower the risk of developing type 2 diabetes in the family.
Nashville, TennesseeAges 6–59 - NCT06440395Recruiting
Healthy eating and exercise program for prediabetes
This study tests a program called Small Steps for Big Changes, which helps people with prediabetes adopt healthier habits. The goal is to see if it works in community settings like YMCAs.
Edmonton, AlbertaAges 18 years+ - NCT06446531RecruitingPhase 1
Preventing diabetes progression in Hispanic adults
This trial tests if a medication can prevent or slow the progression from prediabetes to type 2 diabetes and reduce heart risk. It is for Hispanic adults who are overweight and have prediabetes.
San Antonio, TexasAges 18 years+ - NCT06426277Recruiting
Brazilian diabetes prevention program
This study tests a program that helps people with prediabetes make healthy lifestyle changes to prevent type 2 diabetes. You would get support through your own device at home, with no need for in-person visits.
Goiânia, GoiásAges 18 years+ - NCT06424106Recruiting
Glucagon & fasting insulin in people without type 2 diabetes
This study looks at how glucagon affects insulin release and blood sugar in people who do not have type 2 diabetes. It may help us understand normal glucose control better.
Rochester, MinnesotaAges 25–65 - NCT06424015Recruiting
Insulin pulses during fasting study
This study tests how insulin, given in pulses or continuously, affects your body during a fast. It may help researchers understand better ways to manage blood sugar in people with early blood sugar issues.
Rochester, MinnesotaAges 25–65 - NCT06358261Enrolling by invitation
Diabetes prevention study using a patient activation tool
This trial tests a tool that helps people with prediabetes take steps to prevent diabetes. If you are a patient at a specific Johns Hopkins clinic and use MyChart, you may be able to join.
Lutherville, MarylandAges 25–75 - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT06252038Recruiting
Rural Diabetes Prevention Program
This study tests a diabetes prevention program designed for people in rural Kansas. It helps those with pre-diabetes make healthy lifestyle changes to prevent or delay type 2 diabetes.
Kansas City, KansasAges 18 years+ - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+ - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chandler, ArizonaAges 55 years+ - NCT06118931Recruiting
Time-Restricted Eating for Blood Sugar Control
This study tests whether eating only during a specific daily window helps control blood sugar in people with or at risk for type 2 diabetes. You'll follow a set eating schedule and use a phone app to track your meals.
Toronto, OntarioAges 40 years+ - NCT06115265Recruiting
Ketogenic diet study for prediabetes and weight loss
This trial tests whether a ketogenic diet can help people with prediabetes or high blood sugar improve their health and lose weight. You eat very low-carb, high-fat foods to see if it lowers your blood sugar and reduces your risk of developing diabetes.
Albuquerque, New MexicoAges 18 years+ - NCT05866406Recruiting
Time-restricted eating to improve heart and sugar health
This study tests whether eating only within a set daily time window can improve cardiometabolic health (things like blood sugar and heart-related measures). You may be eligible if you have overweight and borderline/high-risk blood sugar but do not have diabetes and can follow the eating and testing rules.
CambridgeAges 25–75 - NCT05835037RecruitingPhase 4
Zinc supplement study for prediabetes blood sugar control
This study tests whether taking zinc can improve how your body controls blood sugar in people with prediabetes. It may help slow the progression toward type 2 diabetes, but you would need to meet specific health and medication criteria.
Lancaster, PennsylvaniaAges 18–80
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Common questions
- Are there clinical trials for prediabetes?
- Yes. Clin2 currently lists 136 recruiting prediabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.