Clinical trials
Pregabalin clinical trials
Below are recruiting pregabalin clinical trials, each written for real people, not researchers. We’re tracking 38 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07421427Recruiting
Preventing pain after mastectomy with added medication
This trial tests if adding amantadine or duloxetine to the standard drug pregabalin can better prevent chronic pain after a mastectomy. It may help you if you're undergoing a modified radical mastectomy for breast cancer.
CairoAges 18–65 - NCT04666714RecruitingPhase 3
Tested a new medicine to reduce diabetic nerve pain
This Phase 3 study tests Praga formulation to see if it safely reduces nerve pain caused by diabetes. You may qualify if you’re an adult with painful diabetic neuropathy and have certain symptom and pain scores on questionnaires.
Campinas, São PauloAges 18 years+ - NCT07230197Recruiting
Pregabalin and dexmedetomidine for fibromyalgia pain
This trial tests whether combining two medications, pregabalin and dexmedetomidine, works better than standard treatments for fibromyalgia pain. It may help people with moderate to severe fibromyalgia who haven't found relief from non-drug therapies.
BeijingAges 18 years+ - NCT07208357Recruiting
Pregabalin with toludesvenlafaxine for fibromyalgia pain
This study tests a combination of two medications (pregabalin and toludesvenlafaxine) to see if it is safe and effective for people with fibromyalgia whose pain has not improved with non-drug treatments and who have not yet tried standard medications for this condition.
BeijingAges 18 years+ - NCT07186751Recruiting
Pregabalin and venlafaxine for fibromyalgia pain
This trial tests a combination of two medicines (pregabalin and venlafaxine) for people with fibromyalgia whose pain is moderate to severe and has not been helped enough by non-drug treatments. The goal is to see if the combination works better and is safe.
BeijinAges 18 years+ - NCT07171320Recruiting
Combination therapy for fibromyalgia pain
This study tests whether combining two medications, pregabalin (often used for nerve pain) and desvenlafaxine (an antidepressant that can also help with pain), is safe and effective for people with fibromyalgia who still have moderate to severe pain after trying non-drug treatments like exercise or therapy.
BeijingAges 18 years+ - NCT07344467Recruiting
Melatonin vs. Pregabalin for pain and anxiety after spine surgery
This trial compares two medications—melatonin and pregabalin—to see which works better at reducing pain and anxiety after spine surgery. It aims to find a safer, effective option for recovery.
Tanta, El-GharbiaAges 21–60 - NCT07230171Recruiting
Short-term S-ketamine for fibromyalgia pain relief
This trial tests if low-dose S-ketamine, given as a short intravenous infusion, can safely improve fibromyalgia pain and other symptoms for people who haven't gotten enough relief from non-drug treatments. S-ketamine is a fast-acting medicine that blocks pain signals and may help reset how the brain processes pain.
BeijingAges 18 years+ - NCT07196657Recruiting
Testing pregabalin and crisugabalin for fibromyalgia pain
This trial is testing two medications, pregabalin and crisugabalin, to see how safe and effective they are for people with fibromyalgia who have not yet tried prescription treatments. You may qualify if your pain is moderate to severe and nondrug approaches haven't helped enough.
BeijingAges 18 years+ - NCT07157852Recruiting
Testing pregabalin vs mirogabalin for fibromyalgia pain
This study tests two medications, pregabalin and mirogabalin, for people with fibromyalgia who have not yet tried prescription drugs. It aims to see which one works better for pain relief.
BeijingAges 18 years+ - NCT05640453RecruitingPhase 4
Testing pregabalin or dexmedetomidine for post-surgery delirium
This study compares two medicines—pregabalin and dexmedetomidine—to treat confusion (called delirium) after heart bypass surgery. It aims to see which drug works better to reduce delirium symptoms in older adults after coronary artery bypass surgery.
Tanta, El-Gharbia GovernorateAges 65 years+ - NCT06790537RecruitingPhase 4
Pregabalin for itching in diabetes: a controlled study
This trial tests if pregabalin can reduce chronic itching in people with type 2 diabetes. It compares pregabalin against a placebo (inactive pill) to see if itching improves more with the active drug.
Chandigarh, ChandigarhAges 18 years+ - NCT07758920RecruitingPhase 2
New tablet for long-term shingles pain
This trial tests a new tablet called HL-1186 for treating post-herpetic neuralgia (long-lasting pain after shingles). It compares the new drug to pregabalin, a standard treatment, to see if it's safer and more effective.
BeijingAges 18 years+ - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT07635394Recruiting
Pregabalin for Irritable Bowel Syndrome Relief
This study tests whether pregabalin, a nerve-pain medication, can help reduce irritable bowel syndrome (IBS) symptoms like abdominal pain and irregular bowel habits. Researchers want to see if it's safe and effective for people with mild-to-moderate IBS.
Beijing, Beijing MunicipalityAges 18–70 - NCT07606638Enrolling by invitation
Pain Relief Options for Oral Cancer Patients
This study compares two different pain management approaches for people with oral cancer: opioid medication versus a combination of pregabalin (a nerve pain reliever) and naproxen sodium (an anti-inflammatory painkiller). The goal is to see which approach works better and is safer for controlling cancer-related pain.
Lahore, Punjab ProvinceAges 18 years+ - NCT07598474Recruiting
Pregabalin and Movement Therapy for Knee Osteoarthritis Pain
This trial tests whether a nerve pain medication called pregabalin, applied through ultrasound waves to your knee, combined with gentle movement exercises, can reduce pain in advanced knee osteoarthritis. You'll attend 16 treatment sessions over 4 weeks to see if this combination helps.
Faisalābad, Punjab ProvinceAges 40–60 - NCT07593313Recruiting
Treatment for pain after stroke using spinal stimulation
This trial tests a treatment called spinal cord stimulation for people who develop chronic pain after a stroke. The pain is caused by the stroke itself and doesn't respond well to regular pain medicines. The treatment uses a small device to send mild electrical signals to your spinal cord to reduce pain.
Nanchong, SichuanAges 18 years+ - NCT05150795RecruitingEarly Phase 1
Testing pregabalin before surgery versus fentanyl during surgery
This trial compares two medicines used around the time of surgery—pregabalin given by mouth before surgery versus fentanyl given during surgery—to see which better controls pain after the operation. You might join if you’re a generally healthy surgical patient and aren’t using certain related medicines.
CairoAges 21–45 - NCT07377721RecruitingPhase 1
Study of HRS-2129 for diabetic nerve pain
This trial tests a new medicine called HRS-2129 for people with long-term nerve pain caused by diabetes. It aims to see if the drug can safely reduce pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06155916Recruiting
Sleep and nerve pain: a pregabalin study
This study tests whether a nerve pain medication (pregabalin) helps people with long-term nerve pain sleep better. It involves brain scans to see how the medication affects the brain.
Helsinki, HUSAges 18–75 - NCT07275762RecruitingPhase 2
Y-4 for postherpes nerve pain
This trial tests a new drug called Y-4 for people with lingering nerve pain after shingles (postherpetic neuralgia). If you have had pain for more than a month after your rash healed, this study may help find a new treatment option.
Nanjing, JiangsuAges 18 years+ - NCT06935721RecruitingPhase 1
Medication interaction study for healthy adults
This trial studies how a new tablet called Y-4 interacts with pregabalin and riluzole in healthy people. It helps doctors understand how these drugs work together in the body.
Beijing, Beijing MunicipalityAges 18–45 - NCT06969417Recruiting
Comparing two medications for shingles nerve pain
This trial compares two medications (pregabalin and lacosamide) to find out which works better for relieving nerve pain that continues after shingles. If you have this persistent pain and are not already on painkillers, you may be able to join.
Kharan, Punjab ProvinceAges 18–50
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Common questions
- Are there clinical trials for pregabalin?
- Yes. Clin2 currently lists 38 recruiting pregabalin studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pregabalin trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pregabalin trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.