Clinical trials
Primary Aldosteronism clinical trials
Below are recruiting primary aldosteronism clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07304674Recruiting
Primary Aldosteronism and Thinking Ability Study
This study looks at whether primary aldosteronism (a treatable cause of high blood pressure) is linked to memory and thinking problems. It may help understand if managing this condition can protect brain health.
Chengdu, SichuanAges 40 years+ - NCT07378176Recruiting
Study on outlook for primary aldosteronism patients
This study follows people with primary aldosteronism over time to understand their health outcomes. It may help doctors learn how to better treat this condition.
Chengdu, SichuanAges 18–80 - NCT04020783Recruiting
Screening registry for high aldosterone causes of high blood pressure
This study enrolls adults with high blood pressure to record who may have “primary aldosteronism,” a hormone-related cause of high blood pressure. It may help clinicians find better ways to screen and diagnose this condition in people like you.
ShanghaiAges 18–65 - NCT06569589Recruiting
Sodium MRI for primary aldosteronism
This study uses a special MRI to measure sodium levels in your body to better understand and treat primary aldosteronism, a condition that can cause hard-to-control high blood pressure. Participating may help doctors learn how to manage your condition more effectively.
SingaporeAges 21–70 - NCT06635993Recruiting
Testing a PET scan for aldosterone and cortisol condition
This trial tests whether a special PET/CT scan (68Ga-Pentixafor) can accurately identify the subtype of primary aldosteronism in people who also have excess cortisol. It may help determine if surgery is the right treatment for you.
Chongqing, Chongqing MunicipalityAges Any age - NCT07635134Recruiting
Testing a new method to diagnose primary aldosteronism
This study is developing a better blood test to diagnose primary aldosteronism, a condition where the adrenal glands produce too much of a hormone called aldosterone, causing high blood pressure. Researchers are comparing results from healthy volunteers and patients suspected of having this condition to find the right cutoff numbers for the new test.
Beijing, Beijing MunicipalityAges 18–70 - NCT06750172Recruiting
Shorter salt test for primary aldosteronism diagnosis
This study tests if a 2-day version of the oral salt loading test works as well as the standard 3-day test to diagnose primary aldosteronism (a common cause of high blood pressure). If effective, it could make diagnosis faster and easier for patients.
Beijing, Beijing MunicipalityAges 18–70 - NCT06833437Recruiting
New PET scan versus blood test for adrenal condition
This trial tests a special PET scan (68Ga-Pentixafor) to see if it can replace a more invasive blood test (AVS) for finding which adrenal gland is causing high blood pressure and high cortisol levels. It may help patients avoid a complicated procedure.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06513585Recruiting
Two treatments for primary aldosteronism: embolization vs. surgery
This study compares two treatments for primary aldosteronism (a condition causing high blood pressure due to an adrenal gland issue). One treatment is a minimally invasive procedure called superselective embolization, and the other is keyhole surgery. This trial aims to see which is better and safer for patients.
Ürümqi, XinjiangAges 18–60 - NCT06513676Recruiting
Adrenal artery treatment for aldosteronism study
This study tests a procedure that blocks tiny arteries in the adrenal gland to treat high blood pressure and low potassium caused by aldosteronism. It may be an option if you cannot take medications or cannot have surgery.
Ürümqi, XinjiangAges 18–60 - NCT06955286Recruiting
Adrenal insufficiency after adrenal surgery in aldosteronism patients
This study looks at how often adrenal insufficiency happens after surgery for primary aldosteronism, especially in patients who also have an overproduction of cortisol. It helps doctors understand if extra hormone support is needed after surgery.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06616142RecruitingPhase 1/Phase 2
New imaging test for primary aldosteronism
This trial tests a new imaging method called [18F]CETO PET scan to better understand the cause of high blood pressure due to primary aldosteronism (PA). It may help guide treatment decisions without needing more invasive tests.
Groningen, Provincie GroningenAges 18 years+ - NCT07007793RecruitingPhase 3
Study of baxdrostat for primary aldosteronism
This trial tests a new drug called baxdrostat for people with primary aldosteronism, a condition where the adrenal glands make too much aldosterone hormone, often causing high blood pressure. The goal is to see if baxdrostat helps control blood pressure and is safe.
Los Angeles, CaliforniaAges 18 years+ - NCT07605156Recruiting
New imaging scan for rare adrenal hormone tumors
This study tests a special imaging scan (PET/CT) to help doctors identify adrenal tumors that produce too much of two hormones: aldosterone and cortisol. If you have both hormone imbalances confirmed by blood tests and are planning surgery to remove your adrenal gland, this scan may help your doctors see exactly where the tumor is.
BeijingAges 18–80 - NCT05797558Recruiting
Medication versus surgery for one-sided adrenal hormone problem
This trial compares two ways to treat unilateral primary aldosteronism: taking mineralocorticoid receptor antagonist (MRA) pills or having minimally invasive surgery. It may help decide which option works best and is safest for people who can choose surgery.
GothenburgAges 18–70 - NCT05188872Recruiting
PET scan for adrenal hormone condition before and after treatment
This trial uses a special PET scan to look at a hormone gland condition called primary aldosteronism, which can cause high blood pressure. It aims to see if the scan helps doctors plan treatment and check results.
Fuzhou, FujianAges 19–90 - NCT03374215Recruiting
Study hormone causes of high blood pressure in Black adults
This study looks at the body’s hormone signals to understand what causes primary aldosteronism (a condition that can lead to high blood pressure). By comparing clinical results and lab data, researchers hope to improve how the condition is diagnosed and managed, especially in Black participants.
Bethesda, MarylandAges 7–70 - NCT05501080Recruiting
Testing a hormone treatment to improve heart changes in PA
This trial tests whether a treatment called SAAE can improve “ventricular remodeling,” meaning changes in the heart muscle, in people with primary aldosteronism (PA). It may help the heart work more efficiently by targeting the cause of high aldosterone levels.
NanchangAges 18–60 - NCT05561361Recruiting
Test treatment for primary aldosteronism and blood vessel function
This trial studies whether a specific treatment (related to spironolactone/aldosterone support) can improve how well your blood vessels work in people with primary aldosteronism. It may help reduce blood pressure risk by improving blood vessel health.
NanchangAges 18–75 - NCT05638269Recruiting
Study of gut bacteria in people with serious long-term illness
This study looks at the types of gut bacteria in people living in certain parts of China who have serious long-term (chronic) illnesses. The goal is to better understand how gut bacteria differ and may help doctors in the future tailor care.
Chaoyang, Beijing MunicipalityAges 18–75 - NCT06228677Recruiting
Catecholamine levels during adrenal artery embolization
This trial measures hormone levels in blood during a procedure to treat high blood pressure caused by an adrenal gland problem. It may help doctors understand how the body responds during treatment.
Chengdu, SichuanAges 18 years+ - NCT06250699Recruiting
Rapid recovery after urologic surgery
This trial tests a program to help patients recover faster after urologic surgery. It focuses on making sure you heal well and get back to your normal life quickly.
Wuhan, HubeiAges 18–70 - NCT06571084Recruiting
New screening for primary aldosteronism in hypertension
This trial looks for better ways to diagnose primary aldosteronism (PA), a common cause of high blood pressure that can be treated. It may help find people whose hypertension is caused by this condition so they can get the right treatment sooner.
BeijingAges 18–75 - NCT06581744Recruiting
New PET scan for detecting primary aldosteronism
This trial uses a special PET scan to find a condition called primary aldosteronism (too much aldosterone hormone). It may help people who need surgery or who are hard to diagnose with standard tests.
Dalian, LiaoningAges 18 years+
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Common questions
- Are there clinical trials for primary aldosteronism?
- Yes. Clin2 currently lists 51 recruiting primary aldosteronism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary aldosteronism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary aldosteronism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.