Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 721 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05964829Recruiting
Test a leg sleeve to improve walking in multiple sclerosis
This trial studies whether using the Cionic “Neural Sleeve” can improve walking and leg movement in people with multiple sclerosis (MS). It may help if your MS affects mobility, and you can safely wear and tolerate the device during the day.
Cleveland, OhioAges 22–75 - NCT06002581Recruiting
Using brain stimulation to slow Parkinson's disease progression
This study tests if a non-invasive brain stimulation technique called rTMS (repetitive Transcranial Magnetic Stimulation) can slow down Parkinson's disease by improving slow-wave sleep. It aims to help people with mild to moderate Parkinson's who are stable on their medication.
Shanghai, Shanghai MunicipalityAges 50–80 - NCT06007248Recruiting
Study of inflammation-related coronary artery disease
This study compares two types of coronary artery disease: one linked to inflammation (IR-CAD) and the standard type (AS-CAD). If you have had a heart procedure and were recently hospitalized for worsening chest pain, this study may help doctors understand your condition better.
Beijing, Beijing MunicipalityAges 45–64 - NCT06024577Recruiting
Comparing exercise programs for healthy, inactive adults
This study compares different exercise programs to see which one people stick with best. It is for young and middle-aged adults who do not currently exercise regularly and are generally healthy.
San Luis Obispo, CaliforniaAges 18–40 - NCT06033287Recruiting
Real-world study of CDK4/6 inhibitors plus hormone therapy for advanced breast cancer
This study looks at how well CDK4/6 inhibitors combined with hormone therapy work in real-world settings for people with a certain type of advanced breast cancer (HR+/HER2-). It aims to understand the best treatment path and what happens next.
Changsha, HunanAges 18 years+ - NCT06034327Recruiting
Testing a new spectacle lens for slowing myopia in kids 6–8
This study tests a special spectacle lens designed to slow the progression of nearsightedness (myopia) in children aged 6 to 8. It may be a good option for kids who are mildly to moderately nearsighted and haven't used other myopia control treatments.
Oakland, CaliforniaAges 6–8 - NCT06046131Recruiting
Study on factors affecting prostate cancer progression in Guadeloupe and Brittany
This study looks at how genes, environment, and health history affect the growth of prostate cancer. It may help find better ways to treat the disease in people from the Caribbean and Brittany regions of France.
Rennes, Ille-et-VilaineAges 18 years+ - NCT06059144RecruitingPhase 3
Raising blood pressure for worsening small artery strokes
This trial tests if raising blood pressure slightly with a low dose of a medicine called norepinephrine can help people whose stroke symptoms are getting worse. It focuses on small, deep brain artery strokes and aims to improve recovery.
BordeauxAges 18 years+ - NCT06059469RecruitingPhase 2
PSMA scan for advanced triple-negative breast cancer
This trial uses a special scan (PSMA-PET/CT) to see if your breast cancer makes a protein called PSMA. The results might help guide your future treatment.
BrusselsAges 18 years+ - NCT06065371RecruitingPhase 1
Sacituzumab govitecan plus capecitabine for advanced GI cancers
This trial tests a combination of two drugs—sacituzumab govitecan (targeted therapy) and capecitabine (chemotherapy)—for people with advanced stomach, colon, or pancreatic cancer that has stopped responding to standard treatments.
Detroit, MichiganAges 18 years+ - NCT06081400Recruiting
Freezing vs. medication for growing desmoid tumors
This trial compares freezing the tumor (cryoablation) with standard medication for people with desmoid tumors that have grown or caused more symptoms. It aims to see which approach works better when the tumor is not in the belly.
BesançonAges 13 years+ - NCT06088225Recruiting
Myopia prevention with screen distance study
This trial tests if a distance-image screen can help prevent myopia (nearsightedness) from getting worse. It is for children ages 6 to 12 who have had recent changes in their vision.
Beijing, Beijing MunicipalityAges 6–12 - NCT06103669Recruiting
Local treatment for limited cancer spread
This trial tests whether using local treatments (like targeted radiation or ablation) on a few new spots of cancer can help people whose cancer is otherwise stable on their current treatment. It enrolls people with various solid tumors, such as breast, gynecologic, head & neck, sarcoma, or other types.
Sacramento, CaliforniaAges 18 years+ - NCT06112990RecruitingPhase 3
Creatine and exercise to keep muscles strong in prostate cancer
This trial tests if taking creatine plus doing resistance exercises at home can help men with prostate cancer maintain muscle mass and slow cancer growth. You would take creatine or a placebo for 52 weeks and do simple strength exercises twice a week.
Salt Lake City, UtahAges 18 years+ - NCT06127303RecruitingPhase 2
Toripalimab plus cryoablation for lung cancer with limited progression
This trial tests a combination of an immunotherapy drug (toripalimab) and a freezing treatment (cryoablation) for people with advanced non-small cell lung cancer that has started to grow again in only a few spots after initial treatment. It aims to see if this approach can help control the cancer without switching to a completely new therapy.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06148402RecruitingPhase 2
A new combination therapy for advanced colorectal cancer
This trial tests a new combination of three drugs (fruquintinib, camrelizumab, and capecitabine) for people with colorectal cancer that has spread or cannot be removed and has stopped responding to a standard first chemotherapy. It is for those whose cancer progressed after a specific first treatment called FOLFOXIRI.
Guangzhou, GuangdongAges 18 years+ - NCT06155032Recruiting
Clot Removal for Worsening Mild Stroke
This trial tests whether emergency clot removal (endovascular therapy) can help people whose mild stroke gets worse within a week. It's for those who have a blockage in a large brain artery and enough healthy brain tissue to save.
Fuyang, AnhuiAges 18 years+ - NCT06162013RecruitingPhase 2
NAD supplement trial for atypical parkinsonism
This trial tests whether a supplement called nicotinamide riboside (NR) can help people with rare forms of parkinsonism (PSP, MSA, or CBS). It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real supplement or a placebo.
Oslo, OsloAges 30–85 - NCT06162884Recruiting
Using one scan to predict early scarred lung disease
This study uses a single lung scan to find early signs of progressive scarring (fibrosis) in people with pulmonary fibrosis. It may help doctors predict which patients will get worse faster.
Los Angeles, CaliforniaAges 18 years+ - NCT06167330Recruiting
Titan trial: Reducing phantom limb pain
This trial tests a new method to reduce phantom limb pain (pain felt in a missing limb) using gentle electrical stimulation and simple mental exercises. It is for people with one-sided amputations who have had phantom limb pain for at least three months and still have pain episodes now.
Randwick, New South WalesAges 18 years+ - NCT06170177Recruiting
Life after bladder removal surgery study
This study looks at how people feel and their health after having their bladder removed. It aims to understand quality of life after this surgery.
Milan, MIAges 18 years+ - NCT06172595RecruitingPhase 2
PET scan to tell tumor growth from treatment effects in brain cancer
This trial tests whether a special PET scan can tell the difference between actual tumor growth and treatment-related changes in people with aggressive brain cancer (high-grade glioma). If you have had radiation and an MRI shows a growing lesion, this study may help clarify the cause.
SingaporeAges 21 years+ - NCT06174948Recruiting
CUE1 device for Parkinson's and related movement disorders
This trial tests a small device called CUE1 that gives gentle vibrations on the chest to help improve movement and balance in people with Parkinson's disease and similar conditions. It may help if you have trouble with walking or stability.
LondonAges 18 years+ - NCT06178120Recruiting
Study of disease progression in women with X-linked adrenoleukodystrophy
This study follows women with a genetic condition called X-linked adrenoleukodystrophy (ALD) over time to see how the disease progresses. It includes annual check-ups and MRI scans of the brain and spinal cord to monitor changes.
ParisAges 18 years+
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 721 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.