Clinical trials
Prostate Cancer Surgery clinical trials
Below are recruiting prostate cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 457 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07145177RecruitingPhase 1
Lu177-PSMA with liver treatment for advanced prostate cancer
This trial tests a targeted radiation drug (Lu177-PSMA) combined with procedures that treat liver tumors directly (like ablation or radiation). It is for men with prostate cancer that has spread to the liver and is no longer responding to hormone therapy. The goal is to see if this combination works better together.
San Francisco, CaliforniaAges 18 years+ - NCT07129551Recruiting
PSMA-guided surgery for prostate cancer with lymph node spread
This study looks at how well a special type of surgery, guided by PSMA-PET scans, works for men with prostate cancer that has spread to a small number of lymph nodes in the pelvis. It aims to improve outcomes and quality of life.
Hamburg, Free and Hanseatic City of HamburgAges 18–78 - NCT07115914Recruiting
PSMA PET scan to monitor prostate cancer after focal therapy
This trial uses a special PET scan (PSMA PET) to check if prostate cancer returns after focused treatment (focal therapy). It may help find any remaining cancer that standard scans miss.
Chicago, IllinoisAges 18 years+ - NCT07112781Recruiting
Single dose radiation for early prostate cancer
This trial tests whether a single, high dose of radiation can treat low- to intermediate-risk prostate cancer. It may be a shorter and more convenient option for eligible patients.
MoscowAges 18 years+ - NCT07103018RecruitingPhase 1
Study of KTX-2001 for men with advanced prostate cancer
This trial tests a new drug called KTX-2001, possibly combined with another drug (darolutamide), for men whose prostate cancer has spread and stopped responding to standard hormone treatments. The goal is to see if it can help shrink tumors or slow the cancer's growth.
San Francisco, CaliforniaAges 18 years+ - NCT05036226RecruitingPhase 1/Phase 2
COAST therapy for advanced prostate or other solid tumors
This early-phase trial tests the COAST therapy approach in people with advanced solid tumor cancers or advanced prostate cancer that has continued to grow despite standard treatments. The study aims to see how well the treatment works and whether it is safe enough to continue studying.
Charleston, South CarolinaAges 18 years+ - NCT05413850RecruitingPhase 1/Phase 2
Lu-177 PSMA drug study for advanced prostate cancer
This early-stage study tests a radioactive prostate cancer medicine that targets PSMA (a protein on prostate cancer cells). It aims to see how well the treatment works and how safe it is for men whose cancer has spread and shows PSMA on a scan.
Miami, FloridaAges 18 years+ - NCT07090148RecruitingPhase 1
Vaccine plus immunotherapy for prostate cancer that has returned
This trial tests a combination of a DNA vaccine (pTVG-HP) and an immunotherapy drug (nivolumab) along with targeted radiation or ablation of remaining cancer spots. It is for men whose prostate cancer has come back after surgery but hasn't spread widely.
Madison, WisconsinAges 18 years+ - NCT07071207Recruiting
Text reminders after prostate surgery
This trial tests if text message reminders help men recover urinary control after prostate surgery. If you are planning prostate surgery and can use a mobile phone for texts, you may be able to join.
Rochester, New YorkAges 18 years+ - NCT07073794RecruitingPhase 2
Home versus clinic cancer therapy for Black men with prostate cancer
This study looks at whether giving certain prostate cancer treatments at home (instead of the clinic) works as well for Black men. If you qualify, you may get your regular treatment at home with a nurse.
Jacksonville, FloridaAges 18 years+ - NCT07038304RecruitingPhase 2
Radiation for cancer growth in prostate cancer that stopped responding to hormones
This trial tests whether giving precise radiation to a few spots of cancer growth can help control prostate cancer that has stopped responding to hormone therapy. It is for people with up to 3 growing or new spots of cancer on a special scan.
GroningenAges 18 years+ - NCT07028853RecruitingPhase 3
New drug combo for advanced prostate cancer
This study tests whether adding the investigational drug mevrometostat to the standard treatment enzalutamide works better than enzalutamide alone for men with prostate cancer that has spread to other parts of the body (metastatic castration-sensitive prostate cancer). You may benefit if you haven't yet received chemotherapy or similar strong treatments for this stage of cancer.
Huntsville, AlabamaAges 18 years+ - NCT07027124RecruitingPhase 2
High-risk prostate cancer treatment before and after surgery
This trial tests a combination of hormone therapy, a targeted pill (Darolutamide), and an immunotherapy drug (Pembrolizumab) before and after surgery for men with high-risk prostate cancer that has specific genetic features. The goal is to see if this approach helps prevent the cancer from coming back.
New York, New YorkAges 18 years+ - NCT07005154RecruitingPhase 2
Study of ASP5541 for metastatic prostate cancer
This study tests an experimental drug called ASP5541 for men with metastatic prostate cancer (either hormone-sensitive or castration-resistant). It aims to see if the drug can slow cancer growth and improve outcomes when added to standard hormone therapy.
Huntsville, AlabamaAges 18 years+ - NCT07001709RecruitingPhase 4
How abiraterone affects oxycodone in prostate cancer
This study looks at how a common prostate cancer drug (abiraterone) affects how the body processes a painkiller (oxycodone). Men with prostate cancer who take abiraterone will be compared with those who do not, to see if the painkiller works differently.
Deventer, OverijsselAges 18 years+ - NCT05931419Recruiting
Radiation versus surgery for high-risk prostate cancer
This trial compares two standard treatment options—radiation or surgery—for people with high-risk prostate cancer that has not spread. The goal is to see which approach works better for long-term cancer control and side effects.
AlkmaarAges 50–75 - NCT06972628RecruitingPhase 2
177Lu-PSMA-617 for advanced prostate cancer with bone spread
This trial tests a radioactive drug called 177Lu-PSMA-617 to see if it can help men with metastatic castration-resistant prostate cancer that has spread to the bones in a specific pattern (superscan). It's for patients who have already tried hormone therapy and have PSMA-positive tumors.
Houston, TexasAges 18 years+ - NCT06972511RecruitingPhase 2/Phase 3
Maximal tumor removal for prostate cancer that has spread a little
This trial tests a combination of surgery and radiation to remove as much cancer as possible in men with prostate cancer that has spread to a few spots outside the prostate. It aims to see if this aggressive approach can improve long-term outcomes.
ShanghaiAges 18–75 - NCT06970275Recruiting
PET-CT imaging study for cancer surgery patients
This trial uses a special PET-CT scanner to take high-resolution images of cancer tumors that have been surgically removed. The goal is to see how well these images match the results from standard lab tests, such as pathology, and to track long-term outcomes.
AalstAges 18 years+ - NCT00949819Recruiting
Active surveillance study for localized prostate cancer
This trial studies a “watchful waiting” approach, where doctors closely monitor certain prostate cancers with regular checkups and repeat biopsies. It may help people avoid or delay treatment side effects while watching for signs the cancer needs treatment.
Los Angeles, CaliforniaAges 30–85 - NCT06970119RecruitingPhase 1/Phase 2
Study of INR102 for advanced prostate cancer (Phase 1/2)
This trial tests a new investigational drug called INR102 for prostate cancer that has spread and stopped responding to standard treatments. It's given by injection, and the study will check if it's safe and if it can shrink or slow the cancer.
Wuxi, JiangsuAges 18 years+ - NCT06940271Recruiting
Nerve wrap procedure during prostate surgery to help preserve erectile function
This study tests wrapping the nerves next to the prostate with a special tissue graft during prostate cancer surgery. The goal is to see if it helps keep erectile function after surgery.
Jacksonville, FloridaAges 45 years+ - NCT06926374Recruiting
Robotic surgery for gastrointestinal and urologic conditions
This trial tests a new robotic surgery system for common operations on the colon, rectum, prostate, kidney, bladder, stomach, esophagus, gallbladder, and hiatal hernia. It may offer a less invasive option for patients who need surgery for these conditions.
Hong KongAges 18–80 - NCT06822036Recruiting
Starch powder to reduce bleeding in prostate surgery
This trial tests whether applying a dissolvable starch powder (Arister) inside the pelvis during robot-assisted prostate cancer surgery reduces post-surgery bleeding. It is for men whose surgeons plan to spare the nerves controlling erections and who have moderate erectile function beforehand.
Hamburg, Free and Hanseatic City of HamburgAges 45–68
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Common questions
- Are there clinical trials for prostate cancer surgery?
- Yes. Clin2 currently lists 457 recruiting prostate cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.