Clinical trials
Pulmonary Arterial Hypertension clinical trials
Below are recruiting pulmonary arterial hypertension clinical trials, each written for real people, not researchers. We’re tracking 175 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07143448RecruitingPhase 1/Phase 2
Study of HS235 for pulmonary arterial hypertension in adults
This trial tests an experimental drug called HS235 for people with pulmonary arterial hypertension (PAH), a condition of high blood pressure in the lungs. It aims to see if the drug can help improve symptoms and exercise ability.
Tampa, FloridaAges 18 years+ - NCT07137260Recruiting
Walking activity study for pulmonary hypertension patients
This study uses a small wearable sensor to track your walking for 7 days. It aims to understand how pulmonary hypertension affects daily movement and how it changes over time.
Stuttgart, Baden-WurttembergAges 18 years+ - NCT07140484RecruitingPhase 4
Sotatercept for pulmonary arterial hypertension
This study tests a new medication called sotatercept for people with pulmonary arterial hypertension (PAH) who are already on at least two other PAH treatments. The goal is to see if adding sotatercept can improve symptoms and exercise ability.
Edmonton, AlbertaAges 18 years+ - NCT07132788Recruiting
Study of pulmonary arterial hypertension and lean muscle mass
This study looks at how pulmonary arterial hypertension (PAH) affects lean muscle mass. It aims to understand the relationship between PAH and muscle loss, which could help improve treatments and quality of life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07131241Recruiting
A study to predict risk in pulmonary hypertension
This study aims to better predict the future risk for people with pulmonary hypertension (high blood pressure in the lungs) by combining different types of health information collected over time. If you join, researchers will track your health data to build a tool that personalizes care and improves outcomes.
Fuzhou, FujianAges 18 years+ - NCT07120789Recruiting
Understanding pulmonary hypertension knowledge questionnaire
This study aims to validate a questionnaire that measures how well patients understand pulmonary hypertension. If you have been diagnosed with Group 1 Pulmonary Arterial Hypertension (PAH) and can read the questionnaire, you may be able to help researchers make sure it's a useful tool.
São Paulo, São PauloAges 18 years+ - NCT07099144Recruiting
Inhaled nitric oxide for newborns with breathing failure and high blood pressure in the lungs
This trial tests whether inhaled nitric oxide gas can help full-term newborns who have severe breathing problems and high blood pressure in their lungs. It aims to improve oxygen levels and reduce the need for more intensive support.
Guangzhou, GuangdongAges Up to 1 week - NCT06954727Recruiting
Study on first-time right heart catheterization for lung blood pressure
This study is watching people who are having their first right heart catheterization to better understand and manage lung blood pressure problems. It may help doctors improve diagnosis and treatment for people with shortness of breath or suspected pulmonary hypertension.
BeijingAges 14 years+ - NCT06980584Recruiting
Treating nonthrombotic pulmonary hypertension from fibrosing mediastinitis
This study tests a treatment for a rare lung condition called fibrosing mediastinitis, where scar tissue in the chest presses on the lung artery, causing high blood pressure in the lungs. The goal is to see if the treatment can improve your symptoms and quality of life.
BeijingAges 18–85 - NCT07039604Recruiting
Real-world study of PADN for pulmonary artery hypertension
This study tracks how well a procedure called PADN works for people with pulmonary artery hypertension (PAH) in real-life medical settings. PADN is a minimally invasive treatment that targets nerves around the lungs to help lower blood pressure in the arteries.
Nanjing, JiangsuAges Any age - NCT04756076Recruiting
Study heavy metal levels in pulmonary hypertension patients
This study looks at whether heavy metals in the body—and an imbalance of important minerals—are different in people with pulmonary arterial hypertension. It may help researchers understand possible causes and targets for future treatments.
Louisville, KentuckyAges 18 years+ - NCT07013149Recruiting
Switching PAH medicines: does it change your risk?
This study looks at how changing from one PAH medicine (ambrisentan) to another (bosentan) affects your disease risk over time. It compares people who made the switch to those who stayed on ambrisentan.
São Paulo, São PauloAges 18 years+ - NCT06998329Recruiting
PAH diagnosis timing study
This study looks at the timing between first symptoms and diagnosis of pulmonary arterial hypertension (PAH). It aims to better understand how quickly patients get diagnosed after symptoms appear.
São Paulo, São PauloAges 18 years+ - NCT06992440RecruitingPhase 2
Empagliflozin for better right heart function in pulmonary hypertension
This trial tests if a diabetes drug can help people with pulmonary arterial hypertension whose right heart function is reduced. Participants take empagliflozin or a placebo for 24 weeks to see if heart function improves.
Baltimore, MarylandAges 18 years+ - NCT06850792Recruiting
Improving treatment adherence with telemedicine and guidance
This study tests whether regular remote check-ins and guidance can help people with pulmonary arterial hypertension stick to their treatment plan. You would be followed by phone or video from University of Sao Paulo.
São Paulo, São PauloAges 18 years+ - NCT06911632Recruiting
AI-assisted check for pulmonary hypertension in interstitial lung disease
This study uses an AI tool to help doctors decide if you should be tested for pulmonary hypertension (high blood pressure in the lungs), which can be a complication of interstitial lung disease. If the tool suggests you might have it, you may get an echocardiogram (an ultrasound of the heart) and a right heart catheterization (a test to measure pressure in the heart) to find out for sure.
Birmingham, AlabamaAges 18 years+ - NCT05368467Recruiting
Registry study for pulmonary hypertension patients
This is a long-term study that enrolls people who have been diagnosed with pulmonary hypertension (high blood pressure in the lung arteries). It collects medical information over time to better understand the condition and what to expect.
Guangzhou, GuangdongAges Any age - NCT06872112RecruitingPhase 1
Artesunate for pulmonary arterial hypertension safety study
This trial tests if artesunate, a malaria drug, is safe and tolerable for people with pulmonary arterial hypertension (PAH). It may offer a new treatment option for PAH patients whose symptoms persist despite using two or more standard therapies.
Stanford, CaliforniaAges 18–60 - NCT06846554RecruitingPhase 2
Study of APL-9796 for Pulmonary Hypertension with CardioMEMS Monitor
This trial tests a study drug called APL-9796 for people with pulmonary hypertension (PH). It may help by using your CardioMEMS monitor to see how well the drug works. You can take part only if you have a CardioMEMS implant and your PH is not too mild or too severe.
London, LondonAges 18–80 - NCT06804122Recruiting
Exercise rehab for pulmonary arterial hypertension
This trial tests a supervised exercise program for people with pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs. It aims to see if regular exercise can improve your daily function and quality of life.
Tampere, PirkanmaaAges 18 years+ - NCT04808596Recruiting
Pulmonary hypertension registry and blood sample study
This study builds a registry and collection system for people with pulmonary hypertension, confirmed by a specific heart test. By joining, you help researchers learn more about the condition and may support future studies.
Kansas City, KansasAges 18 years+ - NCT06658522RecruitingPhase 4
Sotatercept for right heart function in pulmonary hypertension
This study tests a medicine called sotatercept to see if it can improve how the right side of your heart pumps in people with PAH. It may help you feel better and slow down the disease.
Amsterdam, North HollandAges 18–70 - NCT01347216Recruiting
COMPERA study for lung vessel pressure medicines
This study follows people with different types of high blood pressure in the lungs (pulmonary hypertension) to see how starting specific lung blood vessel medicines affects outcomes. It may help improve how clinicians choose and monitor treatment over time.
LeuvenAges 1 week+ - NCT01501838Recruiting
Registry study for adults with a specific type of pulmonary hypertension
This study is a hospital registry that collects information about adults diagnosed with pulmonary arterial hypertension (a specific type of high blood pressure in the lungs). It helps doctors better understand patients over time and improve care.
Buenos Aires, Buenos AiresAges 17 years+
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Common questions
- Are there clinical trials for pulmonary arterial hypertension?
- Yes. Clin2 currently lists 175 recruiting pulmonary arterial hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary arterial hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary arterial hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
- Idiopathic Pulmonary Arterial Hypertension
- Heritable Pulmonary Arterial Hypertension
- Pulmonary Hypertension
- Arterial Hypertension
- Chronic Thromboembolic Pulmonary Hypertension
- Pulmonary Artery Hypertension
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.