Clinical trials
Radiation Therapy Patient clinical trials
Below are recruiting radiation therapy patient clinical trials, each written for real people, not researchers. We’re tracking 786 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04291378Recruiting
Proton versus standard radiation for early breast cancer
This trial compares two types of radiation—proton therapy and standard photon therapy—for early breast cancer after surgery. It’s mainly for people whose usual radiation plan would put a higher dose to the heart and/or lungs, aiming to reduce that exposure.
AalborgAges 18 years+ - NCT07619599RecruitingPhase 1
PET Scan to Track Lung Cancer Treatment Response
This study uses a special PET imaging scan to help doctors see how well pembrolizumab (an immunotherapy drug) is working against advanced non-small cell lung cancer. You'll receive the scan along with your regular pembrolizumab treatment and possible radiation therapy to help measure treatment response.
Duarte, CaliforniaAges 18 years+ - NCT05412082RecruitingPhase 1
Smart chemo and radiation plan for locally advanced rectal cancer
This Phase 1 study tests a “smart” total treatment plan using chemotherapy (chemo) and radiation before surgery for people with locally advanced rectal cancer. The goal is to see if this approach is safe and can work well while helping plan treatment based on your situation.
Miami, FloridaAges 18 years+ - NCT04671667RecruitingPhase 2
Pembrolizumab vs chemo-radiation after surgery for recurrent head/neck cancer
This trial tests whether pembrolizumab (an immunotherapy drug) works better than the usual chemo plus radiation after surgery for cancer that has come back in the head and neck area. It may help reduce cancer returning or spreading by using your immune system, but eligibility depends on how the cancer came back and your prior treatments.
Birmingham, AlabamaAges 18–79 - NCT04861194Recruiting
Test treatment plans to preserve erections during prostate radiation
This trial studies ways to help preserve erectile function while you receive radiation treatment for prostate cancer. It may help by aiming to protect erections, especially for people at low to intermediate risk.
Utrecht, UtrechtAges 18 years+ - NCT06072586RecruitingEarly Phase 1
Study of BDTX-1535 for brain tumors with EGFR changes
This trial tests a new drug, BDTX-1535, for people with a type of brain tumor called high-grade glioma that has a specific change in the EGFR gene. The study looks at how the drug works in the body and how safe it is for both newly diagnosed and recurrent tumors.
Chandler, ArizonaAges 18 years+ - NCT05903261Recruiting
Study of targeted radiation for rare cancers with limited spread
This observational study follows people with rare solid tumors and a limited number of metastases treated with a focused radiation technique (SBRT). Doctors want to see outcomes after using a strong, curative-intent radiation dose to all active spots.
Rozzano, MilanAges 18 years+ - NCT04512846Recruiting
Radiation for large liver cancer, with or without chemo
This trial compares two treatment approaches for large hepatocellular carcinoma (HCC), a type of liver cancer: stereotactic body radiation therapy (SBRT) alone versus SBRT plus TACE, a catheter-based chemo treatment. It may help decide which approach works better for controlling the tumor when surgery isn’t a good option.
BeijingAges 30–80 - NCT04402788RecruitingPhase 2/Phase 3
Radiation added to immune therapy for extensive small cell lung cancer
This trial tests whether adding radiation therapy to standard immune therapy (atezolizumab) after initial chemo can help people with extensive-stage small cell lung cancer live longer and control the cancer better. You must have a good response (partial response) or stable disease after initial treatment, plus several lab/imaging checks to confirm safety.
Birmingham, AlabamaAges 18 years+ - NCT06583070Recruiting
SABR plus targeted therapy and immunotherapy for advanced kidney cancer
This trial tests combining a precise type of radiation (SABR) with standard targeted therapy and immunotherapy drugs for kidney cancer that has come back or spread. The goal is to see if adding radiation improves outcomes.
Beijing, Beijing MunicipalityAges 18–85 - NCT07044635RecruitingPhase 2
Shorter radiation after robotic surgery for HPV throat cancer
This study tests whether a shorter course of radiation therapy after robotic throat surgery works as well as standard treatment for people with HPV-related throat cancer. It's for patients who have had robotic surgery and whose cancer is HPV-positive.
Salt Lake City, UtahAges 18 years+ - NCT04977375RecruitingPhase 1/Phase 2
Anti–PD-1 treatment plus focused radiation for recurrent glioblastoma
This trial tests a cancer-immunotherapy medicine (an anti–PD-1 antibody, similar to pembrolizumab) combined with precisely targeted radiation to treat glioblastoma that has come back or progressed. It may help your immune system recognize and attack the tumor while the radiation targets the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06708754Recruiting
Light therapy for radiation side effects in head and neck cancer
This study tests if a special light therapy (photobiomodulation) can help reduce tissue stiffness and swelling caused by radiation for head and neck cancer. It may be an option if you finished radiation in the last 3 years and have moderate to severe scarring or swelling.
New York, New YorkAges 18 years+ - NCT06987890Recruiting
Geriatric assessment for older adults with lung cancer getting SBRT
This study looks at how a geriatric assessment can help older adults with early-stage lung cancer who are getting a precise type of radiation therapy called SBRT. The goal is to understand their needs and improve care.
Boston, MassachusettsAges 65 years+ - NCT05100095RecruitingPhase 2
Radiation schedule study for Merkel cell skin cancer
This Phase 2 trial tests a specific radiation timing/dose schedule for Merkel cell carcinoma (MCC), a rare and aggressive skin cancer. It may help by improving control of the cancer after surgery, especially in higher-risk cases (like lymph nodes).
Houston, TexasAges 18 years+ - NCT06306638RecruitingPhase 1/Phase 2
Light therapy after radiation for inoperable airway tumors
This trial tests a new light-activated therapy (interstitial photodynamic therapy) after palliative radiation to shrink inoperable airway tumors and improve breathing. It is for people with solid cancers that block the airway from the outside and cannot be removed with surgery.
Buffalo, New YorkAges 18 years+ - NCT06022159RecruitingPhase 2
Short radiation therapy for older adults with sarcoma
This trial tests a shorter, more convenient radiation schedule (hypofractionated) for older or fragile adults with soft tissue sarcoma in a limb or trunk. It aims to see if this approach is safe and effective before surgery.
BordeauxAges 65 years+ - NCT06069115Recruiting
How radiation affects lung function in breast cancer patients
This study looks at how radiation therapy for breast cancer may affect your lungs over time. Researchers will measure lung function and see if problems develop, so they can better understand and protect patients.
Novosibirsk, Novosibirsk OblastAges 18 years+ - NCT06492759RecruitingPhase 2
High-dose radiation with pembrolizumab and chemo for pd-l1 positive tnbc
This trial tests giving high-dose radiation along with the immunotherapy drug pembrolizumab and chemo to people with a specific subtype of advanced breast cancer (PD-L1 positive triple negative). It may help shrink tumors and keep them from growing.
Atlanta, GeorgiaAges 18 years+ - NCT05189054Recruiting
Radiation retreatment for very central chest tumors
This trial tests a focused form of radiation (SBRT) to treat tumors in the very center of the chest that have already been treated with radiation before. It aims to check safety and whether the tumor can be controlled without causing unacceptable side effects.
Beijing, Beijing MunicipalityAges 18–80 - NCT01985984Recruiting
Predicting outcomes after head and neck radiotherapy
This study looks at how outcomes may be predicted for people with head and neck cancer who receive radiotherapy. It may help doctors better estimate results and tailor follow-up care.
MaastrichtAges 18 years+ - NCT07227792Recruiting
Tongue-out radiation therapy for head and neck cancer
This trial tests if sticking your tongue out during radiation therapy can reduce side effects. It is for people with certain types of head and neck cancer who are getting radiation to the main tumor.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05805371RecruitingPhase 1
PSCA CAR-T cells with or without radiation for prostate cancer
This Phase 1 study tests a prostate cancer treatment made of PSCA-targeted CAR-T cells, with or without radiation, to help control advanced prostate cancer. It aims to find a safe treatment approach and see how well it works in people whose cancer has PSCA.
Duarte, CaliforniaAges 18 years+ - NCT00992303Recruiting
Collecting tissue samples during radiation for people with cancer
This study collects tissue samples from people with cancer while they are getting radiation therapy. It also includes healthy participants, to help researchers compare samples and better understand cancer and treatment.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for radiation therapy patient?
- Yes. Clin2 currently lists 786 recruiting radiation therapy patient studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiation therapy patient trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiation therapy patient trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.