Clinical trials
Radiation clinical trials
Below are recruiting radiation clinical trials, each written for real people, not researchers. We’re tracking 1,045 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06078709RecruitingPhase 2
Pre-surgery radiation and chemo for esophageal cancer
This trial tests a shorter course of radiation combined with chemotherapy (FOLFOX) before surgery for esophageal or stomach-junction cancer. It aims to reduce side effects and still improve outcomes.
Scottsdale, ArizonaAges 18 years+ - NCT06078813RecruitingPhase 1/Phase 2
Higher dose spine radiation for limited spread cancers
This trial tests a higher dose of focused radiation (SABR) for people whose solid cancer has spread to the spine in a few spots. The goal is to control those tumors with fewer side effects.
CorkAges 18 years+ - NCT05972655RecruitingPhase 2
Testing shorter rectal radiation with chemotherapy plus immunotherapy
This Phase 2 study tests whether a shorter course of radiation, combined with chemotherapy (CAPOX) and an immunotherapy drug (tislelizumab), can control middle and low rectal cancer. It may also help people who strongly want to keep their anus, if the cancer and overall health fit the study rules.
Hanzhou, ZhejiangAges 18–75 - NCT05903261Recruiting
Study of targeted radiation for rare cancers with limited spread
This observational study follows people with rare solid tumors and a limited number of metastases treated with a focused radiation technique (SBRT). Doctors want to see outcomes after using a strong, curative-intent radiation dose to all active spots.
Rozzano, MilanAges 18 years+ - NCT05851924RecruitingPhase 2
Nalirifox plus radiation for nonmetastatic pancreatic cancer
This trial studies Nalirifox (chemotherapy) given together with radiation therapy for pancreatic ductal adenocarcinoma that has not spread to distant organs. It may help shrink the cancer and improve local control, especially when surgery is not an option right now.
Basking Ridge, New JerseyAges 18 years+ - NCT05727410RecruitingPhase 2
Nivolumab and chemotherapy before surgery and radiation for salivary cancer
This Phase 2 study tests giving nivolumab plus docetaxel and cisplatin before surgery and radiation for certain resectable, high-grade salivary gland cancers. It aims to shrink or control the cancer early to improve outcomes after treatment.
SeoulAges 19 years+ - NCT05265208RecruitingPhase 2
Radiation plus chemo after liver surgery for bile duct cancer
This trial studies giving a special internal radiation treatment along with capecitabine (a chemotherapy) for liver cancer related to bile ducts, after planned surgical removal. It may help improve control of the cancer in cases where surgeons think the edges of the removed tumor may be too close.
Rennes, Brittany RegionAges 18 years+ - NCT05349552Recruiting
Radiation for lung or chest cancers in specific locations
This trial studies how safe and effective a type of focused radiation called SBRT is for cancer tumors in certain chest locations. It’s meant for people whose tumor is small (up to 5 cm) and who don’t have widespread, uncontrolled spread.
Beijing, Beijing MunicipalityAges 18–80 - NCT04992780RecruitingPhase 2
Hypo-fractionated radiation versus standard radiation for lung cancer
This study compares two different radiation schedules for stage III non-small cell lung cancer, both combined with chemotherapy and immunotherapy. It aims to see whether giving radiation in a different way can work as well (or better) and be safe while treating the cancer.
Kansas City, KansasAges 18 years+ - NCT05096715RecruitingPhase 1
Testing atezolizumab plus bevacizumab with SBRT for advanced liver cancer
This Phase 1 trial tests how well a combination treatment works for liver cancer that cannot be removed with surgery or other local treatments. It combines two immune/targeted medicines with a focused type of radiation (SBRT) to control the tumors.
Boston, MassachusettsAges 18 years+ - NCT04996914Recruiting
Radiation after chemo-embolization for liver cancer patients
This trial studies giving targeted radiation after a liver procedure called trans-arterial chemoembolization for hepatocellular carcinoma (HCC). It may help control the cancer in people who cannot have surgery or transplant.
Aachen, North Rhine-WestphaliaAges 18–80 - NCT04983095Recruiting
Targeted radiation for a few prostate cancer metastases
This trial looks at whether a precise form of radiation (stereotactic body radiotherapy) can control a small number of prostate cancer spots seen on a special scan (PSMA PET/CT). It may help by treating limited metastases while avoiding unnecessary treatment elsewhere.
Lund, LundAges 18 years+ - NCT04678258Recruiting
Study without x-ray guidance for treating atrial flutter
This trial tests a way to do a heart procedure for “atrial flutter” with less or no x-ray use. It may help reduce radiation exposure while still aiming to cure the abnormal rhythm.
Fürth, BavariaAges 18 years+ - NCT05071105Recruiting
Short-course radiation for early breast cancer in older women
This study looks at a brief type of radiation called SBRT given soon after starting hormone therapy for certain early breast cancers in women age 75 and older. It may help treat the cancer locally while aiming to be easier to receive than longer radiation schedules.
Rome, RomeAges 75 years+ - NCT05085496RecruitingPhase 1
Radiation plus atezolizumab for advanced skin cancer
This Phase 1 trial studies adding atezolizumab (an immune therapy) to radiation for people with hard-to-remove or borderline-resectable cutaneous squamous cell carcinoma (cSCC). The goal is to see whether this combination can better control the cancer and whether the treatment is safe.
Duarte, CaliforniaAges 18 years+ - NCT04316039RecruitingPhase 2/Phase 3
Radiation alone or with temozolomide for brain tumor after surgery
This trial compares standard radiation therapy versus radiation plus a chemotherapy medicine called temozolomide in people with a newly diagnosed low-grade (WHO grade II) brain glioma after surgery. It’s designed to see if adding temozolomide improves outcomes while managing side effects.
Chengdu, SichuanAges 18–70 - NCT04020276Recruiting
Adaptive MRI radiation for liver metastases
This study tests a radiation treatment that uses real-time MRI (an imaging scan) to guide the dose for liver metastases. It may help control tumors while aiming to better protect nearby healthy liver tissue.
Madison, WisconsinAges 18 years+ - NCT04276870RecruitingPhase 2
CD19 gene-modified cells for high-risk B-cell leukemia
This Phase 2 trial studies CD19 “redirected” cells made from your own blood to treat certain high-risk or relapsed B-cell acute lymphoblastic leukemia (B-ALL). It may help by targeting cancer cells that carry a protein called CD19.
Philadelphia, PennsylvaniaAges birth–29 years - NCT02559752Recruiting
Computer brain testing during proton radiation for childhood tumors
This trial studies how children’s thinking and learning skills change while they receive proton beam radiation for a brain/spinal cord tumor. It uses computer-based cognitive tests to better understand brain effects during treatment, which may help future care.
St Louis, MissouriAges 4–21 - NCT04428671RecruitingPhase 1
Cemiplimab before and after surgery for high-risk skin cancer
This Phase 1 trial tests the drug cemiplimab given before and after surgery to reduce the chance that high-risk cutaneous squamous cell cancer comes back. You may be a candidate if your cancer is high-risk on pathology or imaging and is planned for surgical removal.
Atlanta, GeorgiaAges 18 years+ - NCT04512846Recruiting
Radiation for large liver cancer, with or without chemo
This trial compares two treatment approaches for large hepatocellular carcinoma (HCC), a type of liver cancer: stereotactic body radiation therapy (SBRT) alone versus SBRT plus TACE, a catheter-based chemo treatment. It may help decide which approach works better for controlling the tumor when surgery isn’t a good option.
BeijingAges 30–80 - NCT03049072Recruiting
Registry for people treated with ion beam therapy at MedAustron
This trial is a patient registry that collects information from people treated with ion beam therapy at MedAustron. It helps researchers understand treatment patterns and outcomes and may improve care for future patients.
Wiener Neustadt, Lower AustriaAges Any age - NCT06767007RecruitingPhase 2
Radiation plus immunotherapy for recurrent rectal cancer
This trial studies a combination of SBRT (a precise kind of radiation) and an immunotherapy drug (PD-1 antibody) for people whose rectal cancer has come back in the pelvis and cannot be removed by surgery. The goal is to see if this treatment can shrink the tumor or stop it from growing.
Guangzhou, GuangdongAges 18–75 - NCT00992303Recruiting
Collecting tissue samples during radiation for people with cancer
This study collects tissue samples from people with cancer while they are getting radiation therapy. It also includes healthy participants, to help researchers compare samples and better understand cancer and treatment.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for radiation?
- Yes. Clin2 currently lists 1,045 recruiting radiation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.