Clinical trials
Radiosurgery clinical trials
Below are recruiting radiosurgery clinical trials, each written for real people, not researchers. We’re tracking 68 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06557512Recruiting
Focused radiation after surgery for certain meningiomas
This study tests a type of focused radiation therapy (called stereotactic radiosurgery) given after surgery for certain meningiomas. The goal is to see if this treatment helps prevent the tumor from coming back, and to check its safety.
San Francisco, CaliforniaAges 18 years+ - NCT05679427Recruiting
Surgery-like radiation for limited bone spread
This trial compares two types of highly focused radiation (ablative radiosurgery versus stereotactic radiation in 5 sessions) for people with a small number of metastases in the bone. It aims to find which approach controls these spots with fewer side effects while keeping the treatment “radical,” meaning trying to wipe out the targeted lesions.
Milan, MIAges 18–85 - NCT04218617RecruitingPhase 2
One vs two radiation treatments for spine metastases
This trial tests whether giving radiation to a spine metastasis in one dose works as well as giving it in two smaller doses. It aims to control tumors while keeping side effects and risk to the spinal cord low.
Cleveland, OhioAges 18 years+ - NCT06204315RecruitingPhase 2
Spine radiosurgery for spinal cord compression
This trial tests a precise radiation technique for people whose spinal tumors are very close to the spinal cord or nerves. It aims to safely give higher radiation doses while limiting damage to the cord.
Houston, TexasAges 18 years+ - NCT06863324Recruiting
Impact of radiation sensitivity on late side effects of facial pain radiosurgery
This study looks at whether how sensitive people are to radiation affects late side effects after radiosurgery for trigeminal neuralgia. It may help doctors better predict and prevent long-term problems.
Nice, Alpes-maritimesAges 18 years+ - NCT06741085RecruitingPhase 2
Radiosurgery plus standard care for lung cancer spread to brain
This trial tests if adding stereotactic radiosurgery (focused radiation) to standard drug therapy is safe and effective for people with EGFR-mutant non-small cell lung cancer that has spread to the brain. It aims to improve control of brain metastases while continuing targeted therapy.
Miami, FloridaAges 18 years+ - NCT05985148RecruitingPhase 1
Radiosurgery for chronic chest or stomach wall pain
This trial tests whether a precise, one-time radiation treatment (stereotactic radiosurgery) can relieve long-term pain in the chest or stomach wall. It may be an option for people whose pain is not well controlled with standard pain medicines.
Basking Ridge, New JerseyAges 18 years+ - NCT06287515RecruitingPhase 1
Radiation to the pituitary gland for cancer pain
This study tests a focused radiation treatment on a small gland in the brain to see if it can relieve cancer-related pain that hasn't been controlled by standard treatments like painkillers or other therapies. It may help patients whose pain limits their daily life.
Houston, TexasAges 18 years+ - NCT07655583Recruiting
Skipping radiation after brain surgery
This study is for people with melanoma or lung cancer that has spread to the brain and who have had surgery to remove the brain tumor. It looks at whether it is safe to skip the usual radiation treatment after surgery, while taking a targeted drug therapy that is known to be effective in the brain.
Houston, TexasAges 18 years+ - NCT03550391RecruitingPhase 3
Surgery-like brain radiation vs avoiding the memory center
This trial compares two ways of giving radiation to the brain for people with 5 or more brain metastases: focused stereotactic radiosurgery, or a whole-brain approach that tries to spare the memory area (with memantine). It aims to see which method better protects thinking and memory while still treating the tumors.
Tucson, ArizonaAges 18 years+ - NCT03750227RecruitingPhase 3
Radiation before or after brain tumor surgery
This study compares giving focused, high-precision radiation before or after surgery for brain metastases. It aims to see which timing works best to control tumors and improve outcomes.
Scottsdale, ArizonaAges 18 years+ - NCT04343157RecruitingPhase 2
Image-guided focused radiation to protect thinking in brain metastases
This Phase 2 trial tests a brain radiation technique that aims to treat up to a few brain metastases while sparing areas important for thinking and memory. It may help people keep cognitive abilities better than with more brain-wide radiation approaches.
San Diego, CaliforniaAges 18 years+ - NCT04859335Recruiting
Tracking balance and inner-ear function after Gamma Knife for schwannoma
This study looks at how balance and inner-ear (vestibular) function change after Gamma Knife radiosurgery for vestibular schwannoma. It may help doctors understand what to expect during recovery and how well these functions improve.
ToulouseAges 18–65 - NCT05023772Recruiting
Laser and targeted radiation for spine metastases
This trial tests a combination treatment that uses a laser and focused radiation to shrink tumors in the spine and help stabilize the area near the spinal cord. It’s meant for adults with certain types of solid cancers that have limited spread in the spine and who are not good candidates for surgery.
Detroit, MichiganAges 18 years+ - NCT05030298RecruitingPhase 1
Pre-op focused radiation for aggressive brain tumor
This early-phase study tests a type of very targeted radiation given before surgery for people with a high-grade (aggressive) brain tumor. The goal is to see if this approach is safe and potentially improves treatment, while collecting tumor and blood samples for research.
Phoenix, ArizonaAges 18 years+ - NCT05102747Recruiting
Surgery-like brain radiation for up to 5 metastases
This trial compares two ways of giving focused radiation to the brain for people with a limited number of brain metastases. It aims to see which schedule works best (and is likely best for costs and quality of life).
BordeauxAges 18 years+ - NCT05124236Recruiting
Pre-surgery vs post-surgery focused radiation for brain metastases
This trial compares two ways of giving focused radiation for brain metastases: before surgery or after surgery. It aims to see which timing works better to control tumors while keeping you safe.
InnsbruckAges 18 years+ - NCT05419076RecruitingPhase 2
SRS radiation for small cell lung cancer with brain spread
This Phase 2 trial tests a type of focused radiation (stereotactic radiosurgery, or SRS) for people with small cell lung cancer that has spread to the brain. It looks at whether this approach can treat brain metastases when the cancer has limited to a certain number of spots.
Basking Ridge, New JerseyAges 18 years+ - NCT05522660RecruitingPhase 3
Immunotherapy or targeted therapy with focused brain radiation
This Phase 3 study tests whether immunotherapy or targeted medicine, with or without a one-time focused brain radiation procedure, can control brain metastases from melanoma or non-small cell lung cancer. It mainly enrolls people who have no (or minimal) brain symptoms and are newly diagnosed in the brain (except for certain recent brain surgery).
NaplesAges 18 years+ - NCT05545007Recruiting
Pre-op vs post-op focused radiation for large brain metastases
This study compares giving focused, high-dose radiation before surgery versus after surgery for people with large brain metastases. The goal is to see which timing works best to control the tumors and help neurological outcomes.
Brescia, BresciaAges 18 years+ - NCT05641441Recruiting
Study hearing side effects after targeted treatment for vestibular schwannoma
This study looks at how targeted brain/skull-base treatment for a vestibular schwannoma may affect hearing (ear “ototoxicity,” meaning damage to hearing). It may help doctors better predict and prevent hearing problems in people treated for this tumor.
GenevaAges 18 years+ - NCT05868928Recruiting
MRI study of brain metastasis relapse after focused radiation
This study looks at MRI scan patterns to estimate the risk of brain metastases coming back after stereotactic radiosurgery (such as Gamma Knife or CyberKnife). It mainly helps by finding imaging clues that can guide follow-up after treatment.
SeoulAges 18 years+ - NCT06070233Recruiting
Radiosurgery for spasticity after stroke or injury
This trial tests a non-invasive radiation treatment (radiosurgery) to reduce severe muscle stiffness (spasticity) that hasn't improved with other treatments. It may help people with spasticity caused by stroke, spinal cord injury, or cerebral palsy.
Winter Park, FloridaAges 16 years+ - NCT06649058RecruitingPhase 2
Study on combining drugs and radiation for brain metastases
This trial is for people with cancer that has spread to the brain (brain metastases). It tests a new approach where you start a systemic therapy (drugs that travel through your body) and later add focused radiation to the brain tumors, instead of treating them right away. The goal is to see if this sequence works well and avoids unnecessary side effects.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for radiosurgery?
- Yes. Clin2 currently lists 68 recruiting radiosurgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiosurgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiosurgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.