Clinical trials
Recurrence clinical trials
Below are recruiting recurrence clinical trials, each written for real people, not researchers. We’re tracking 1,384 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06434610RecruitingPhase 2
Study of B013 plus paclitaxel for ovarian cancer
This study tests a new drug (B013) combined with a standard chemotherapy (paclitaxel) for people with ovarian cancer that has come back after platinum-based treatment. The goal is to see if the combination works better than the current options.
BeijingAges 18–75 - NCT05658640RecruitingPhase 1/Phase 2
Testing trametinib and steroid plus chemo for relapsed blood cancers
This early-phase trial tests whether adding trametinib and dexamethasone to standard chemotherapy can improve outcomes for children whose blood cancer has come back or did not respond. Because it is a Phase 1/2 study, the main goal is to see safety and learn the best way to treat your specific cancer type.
ViennaAges 1–21 - NCT05751044RecruitingPhase 1/Phase 2
Study of four medicines for children with difficult blood cancers
This Phase 1/2 trial tests a combination of medicines (dasatinib, venetoclax, dexamethasone, cyclophosphamide, and cytarabine) in children and teens whose blood cancer has come back or did not respond to treatment. It aims to see whether this approach can control the cancer while checking what doses are safe.
ViennaAges 1–21 - NCT05745714RecruitingPhase 1/Phase 2
Targeted triple-combination treatment for children with relapsed blood cancers
This Phase 1/2 study tests a multi-drug combination (ruxolitinib, venetoclax, dexamethasone, plus chemotherapy) for children whose blood cancer has come back or did not respond. It aims to reduce the cancer by targeting specific genetic changes and may offer a new option when standard treatments have not worked.
ViennaAges 1–21 - NCT06404242Recruiting
Plaque features predict repeat stroke after middle cerebral artery blockage
This study looks at people who recently had a stroke caused by hardening of the arteries in the middle cerebral artery, a major blood vessel in the brain. The researchers use special MRI scans to see if the plaque (the fatty buildup) can predict whether another stroke might happen.
Ho Chi Minh City, Ho Chi Minh CityAges 45–100 - NCT06401772Recruiting
Body posture to prevent repeat brain bleed after surgery
This trial tests whether lying in a specific body position after surgery can help prevent a chronic subdural hematoma from coming back. It is for people aged 60 and older who have had a small drainage procedure for this type of brain bleed.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT06406725Recruiting
Detecting vocal cord issues with noninvasive breathing test
This study tests whether a noninvasive breathing support device can detect vocal cord movement problems in children who had heart or airway surgery. It may avoid the need for a scope test.
Queens, New YorkAges 1 day–18 years - NCT04846803Recruiting
Prevent repeat UTIs using bacterial interference treatments
This trial studies a new way to help stop urinary tract infections (UTIs) from coming back by using “bacterial interference” (changing the bacteria in the urinary system). It may help people who have had UTIs keep returning despite past treatments.
Aarhus NAges 18–90 - NCT06397560Recruiting
Proton radiation for returning brain tumors
This trial tests a new type of proton radiation therapy given at a lower dose rate to treat brain tumors that have come back after previous radiation. The goal is to see if it's safe and effective.
Boca Raton, FloridaAges 18 years+ - NCT06396312Recruiting
Predicting lithium response in difficult depression
This study looks at how to predict which people with hard-to-treat depression will benefit from adding lithium to their antidepressant. If you have treatment-resistant depression and are considering lithium, this trial may help find the best treatment for you.
Munich, BavariaAges 18 years+ - NCT06386224Recruiting
Online pain self-management for pancreatitis pain
This study tests an online pain-management program for adults with chronic or recurrent acute pancreatitis. The program is done on your own device (or a loaner iPad) and is designed to help you learn skills to cope with pain and improve daily life.
Seattle, WashingtonAges 18 years+ - NCT06386315RecruitingPhase 2
Lower dose radiation for slow-growing lymphoma
This trial tests whether giving a lower dose of radiation than usual works well for people with slow-growing B-cell lymphomas. It aims to reduce side effects while still controlling the disease.
Scottsdale, ArizonaAges 18 years+ - NCT06369285RecruitingPhase 2
Alisertib and hormone therapy for advanced breast cancer
This trial tests a new drug, alisertib, combined with hormone therapy for people with HR-positive, HER2-negative breast cancer that has spread or come back and is no longer curable. It may be an option if you've already tried at least two hormone therapies and a CDK4/6 inhibitor.
Birmingham, AlabamaAges 18 years+ - NCT06366490RecruitingPhase 1
Personalized vaccine for recurrent ovarian cancer
This trial tests a personalized cancer vaccine made from your own tumor cells. It is for women with advanced ovarian, fallopian tube, or primary peritoneal cancer that has returned after at least one round of platinum chemotherapy.
Duarte, CaliforniaAges 18 years+ - NCT06344130RecruitingPhase 1
Shorter radiation for recurrent glioblastoma
This trial tests a new, shorter course of radiation therapy (called hypofractionation) for people with glioblastoma that has come back. It is for patients who have already had radiation and are doing well enough to consider another round.
Bethesda, MarylandAges 18–120 - NCT06326190RecruitingPhase 2
Study of radioactive drug for recurrent meningioma
This trial tests a radioactive drug called 177Lu-DOTATATE for people with recurrent meningioma (a type of brain tumor) that has grown after surgery and radiation. The drug targets a protein on the tumor cells and delivers radiation directly to them.
InnsbruckAges 18 years+ - NCT06330064RecruitingPhase 1/Phase 2
Study of a new drug for advanced solid tumors
This study tests a new drug called Ifinatamab Deruxtecan (I-DXd) for people with several types of advanced cancer that has grown despite standard treatments. The drug is designed to target and attack cancer cells directly, potentially shrinking tumors or slowing their growth.
Los Angeles, CaliforniaAges 18 years+ - NCT06306014RecruitingPhase 1/Phase 2
Study of a new therapy to prevent C. diff recurrence
This study tests a new live bacteria product (EXL01) given with vancomycin to prevent C. diff from coming back. It is for people who have already had C. diff two or more times and are at high risk of another infection.
AnnecyAges 18 years+ - NCT06314958Recruiting
Follow-up after colorectal cancer treatment
This study follows people who have finished treatment for stage II (high-risk) or stage III colorectal cancer and are now cancer-free. Researchers want to learn more about which factors might predict if the cancer will come back, so they can better personalize follow-up care.
Monrovia, CaliforniaAges 18 years+ - NCT05705570RecruitingPhase 1
CAR-T for CD19-positive relapsed or resistant blood cancers
This trial tests a type of immune treatment (CAR-T cells) for blood cancers that have come back or did not respond after standard treatments. It is for tumors that have CD19 on their cells, aiming to reduce the cancer and improve remission chances.
São Paulo, São PauloAges 2–70 - NCT05510622Recruiting
Uterine microbiome study for recurrent pregnancy loss
This study looks at the normal bacteria and other microorganisms in the uterus to better understand recurrent pregnancy loss. You may be in a group with recurrent pregnancy loss or in a comparison group without pregnancy loss, and you’ll be asked to meet specific health and timing rules for samples.
Ho Chi Minh City, Ho Chi Minh CityAges 18–38 - NCT06253117RecruitingPhase 2
Testing pirfenidone to prevent repeat pancreatitis attacks
This trial tests if pirfenidone, an anti-scarring drug, can reduce the number of repeat episodes of acute pancreatitis. You may be eligible if you've had two or more pancreatitis attacks at least three months apart and are not having an active attack right now.
Birmingham, AlabamaAges 18–85 - NCT06265285RecruitingPhase 2
Nivolumab at home vs. clinic for cancer treatment
This study compares giving the immunotherapy drug nivolumab as a shot under the skin at home versus in the clinic. It is for people with certain cancers who are already taking or starting nivolumab.
Jacksonville, FloridaAges 18 years+ - NCT06254326RecruitingPhase 1
Immune cell therapy for recurrent oligodendroglioma
This trial tests a personalized immune cell therapy for adults with a specific type of brain tumor (oligodendroglioma) that has come back. The treatment uses your own immune cells to target the tumor.
Gainesville, FloridaAges 18–89
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Common questions
- Are there clinical trials for recurrence?
- Yes. Clin2 currently lists 1,384 recruiting recurrence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.