Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04489719Recruiting
Testing whether DNA repair changes affect radium-223 response
This study looks at whether differences in a cancer’s DNA repair system can predict how well radium-223 works for men with prostate cancer that has spread to the bones. It may help researchers choose better treatment for people with bone metastatic, castration-resistant prostate cancer.
Baltimore, MarylandAges 18 years+ - NCT07516509Recruiting
How muscle cells respond to blood sugar in different body types
This research study examines how muscle cells handle blood sugar differently depending on whether someone is lean or has obesity, and whether their body resists insulin. Researchers will take small muscle samples to understand the genetic differences, which may help develop better treatments for insulin resistance and metabolic health.
Orlando, FloridaAges 30–65 - NCT06236139RecruitingPhase 1/Phase 2
Immune cells plus hormone therapy for advanced prostate cancer
This study tests a new type of treatment that uses your own immune cells (engineered to target prostate cancer) combined with a hormone therapy drug. It is for men with advanced prostate cancer that has stopped responding to standard hormone treatments.
Seattle, WashingtonAges 18 years+ - NCT07156552Recruiting
Protein and exercise to prevent muscle loss after weight loss surgery
This trial tests whether taking extra protein and doing resistance training helps people keep their muscle mass after bariatric surgery (stomach reduction or gastric bypass). If you're scheduled for this surgery and can follow the program, you may be able to join.
AmsterdamAges 18 years+ - NCT04585958RecruitingPhase 1
DS-8201a plus olaparib for HER2-positive platinum-resistant ovarian cancer
This trial tests whether combining DS-8201a with olaparib can slow or shrink HER2-positive ovarian cancer that has returned quickly after platinum chemotherapy. It’s a Phase 1 study, meaning it mainly checks safety and finds the best dose, while also looking for signs of anti-cancer activity.
Phoenix, ArizonaAges 18 years+ - NCT06526858Recruiting
Laparoscopic kidney nerve treatment for resistant hypertension
This study tests a new treatment called HyperQure RDN, a laparoscopic (keyhole) surgery that targets nerves near the kidneys to lower blood pressure in people with resistant hypertension. If you have tried multiple medications but your blood pressure is still high, this procedure might offer an alternative approach.
Orange, CaliforniaAges 22–80 - NCT06067841RecruitingPhase 1
New drug for advanced prostate cancer
This study tests a new drug (BMS-986460) for people with advanced prostate cancer that has stopped responding to hormone therapy. It aims to see if the drug can shrink or slow the cancer.
Palo Alto, CaliforniaAges 18 years+ - NCT06784336RecruitingPhase 2
Testing starch and a drug after stem cell transplant
This trial tests if adding a special starch and a drug called deferasirox can improve recovery for people who have a stem cell transplant for blood disorders. The starch may help with gut health and the drug reduces iron, which might help prevent complications.
Ann Arbor, MichiganAges 18 years+ - NCT07493512RecruitingPhase 1
Study of xaluritamig for metastatic prostate cancer
This trial tests a new drug called xaluritamig for men with metastatic prostate cancer that is resistant to hormone therapy. It is designed for those who have already tried certain hormone pills and one type of chemotherapy, and aims to see if the drug can shrink tumors or slow cancer growth.
Denver, ColoradoAges 18 years+ - NCT06594900Enrolling by invitation
Muscle strength in kids before puberty, with training
This study looks at how resistance training affects muscle function in prepubertal children. It compares changes from training to normal growth, and aims to help kids get stronger safely.
Basel, BasellandschaftAges 7–11 - NCT06434610RecruitingPhase 2
Study of B013 plus paclitaxel for ovarian cancer
This study tests a new drug (B013) combined with a standard chemotherapy (paclitaxel) for people with ovarian cancer that has come back after platinum-based treatment. The goal is to see if the combination works better than the current options.
BeijingAges 18–75 - NCT05225363RecruitingPhase 1
CAR T therapy for ovarian cancer that no longer responds to platinum
This Phase 1 study tests a one-time treatment made from your immune cells (CAR T) to attack a protein found on some ovarian cancer cells. It is for people whose ovarian cancer has come back or worsened after platinum chemotherapy, aiming to see safety and early signs of benefit.
Duarte, CaliforniaAges 18 years+ - NCT03887715RecruitingTeam says not enrolling
VNS device for long-term depression that hasn’t improved
This trial studies whether a vagus nerve stimulation (VNS) device can reduce symptoms of treatment-resistant depression. Participants either receive the VNS treatment or a no-stimulation control, to compare safety and effectiveness.
Birmingham, AlabamaAges 18 years+ - NCT07640191Recruiting
New Nerve Stimulation Device for Hard-to-Treat Epilepsy
This study tests a new implanted device that stimulates the vagus nerve (a major nerve in your neck) to help reduce seizures in people whose epilepsy doesn't respond well to medications. The device is surgically placed under the skin and may help lower how often you have seizures.
South Brisbane, QueenslandAges 4–75 - NCT06843668RecruitingPhase 2/Phase 3
Best ways to give colistin for tough infections in the ICU
This study tests different ways of giving the antibiotic colistin to patients in the ICU with infections that are hard to treat. The goal is to find the best dosing schedule to help you fight the infection more effectively.
BuraidahAges 18 years+ - NCT06743269Recruiting
Breathing Training for Stress and Sleep in Midlife Women
This study tests a simple breathing exercise (inspiratory muscle strength training) to see if it can help reduce stress and improve sleep for midlife women who have hot flashes. If you're between 45-60, have hot flashes, and don't smoke, you may be able to join.
Rochester, MinnesotaAges 45–60 - NCT06656117Enrolling by invitation
Elliptical vs. resistance training for heart bypass recovery
This study compares elliptical training with resistance training to see which better improves heart and lung function in patients who have had coronary artery bypass grafting (CABG). It aims to help you recover more fully during phase III cardiac rehab.
Sialkot, Punjab ProvinceAges 45–55 - NCT06321536RecruitingPhase 2
Testing microbiota therapy for resistant bacteria in the gut
This study tests a treatment made from healthy donor stool (called microbiota therapy) given as an enema or through a feeding tube. It aims to help people who carry resistant bacteria that are hard to treat, by reducing or clearing those bacteria from the gut.
Atlanta, GeorgiaAges 18 years+ - NCT05998135RecruitingPhase 2
Testing Atovaquone for Platinum-Resistant Ovarian Cancer
This trial tests whether a drug called atovaquone, already used for other conditions, can help people with ovarian cancer that no longer responds to platinum chemotherapy. It aims to find a new treatment option for this hard-to-treat type of cancer.
Atlanta, GeorgiaAges 18 years+ - NCT06001333Recruiting
Fecal transplant to clear superbugs from the gut
This study tests whether a fecal transplant (FMT) can remove certain antibiotic-resistant bacteria from your gut. It might help people who carry superbugs like CPE or VRE but aren't currently on antibiotics.
Chuncheon, Gangwon-doAges 20 years+ - NCT06069505Recruiting
Testing for drug-resistant fungus in blood or fluid
This study is testing a new blood or fluid test that may find drug-resistant fungus in people with a weakened immune system who have a serious lung infection. The results could help doctors choose the right medicine faster.
Rotterdam, South HollandAges 18 years+ - NCT06058455Recruiting
Online sexual assault resistance program for college women
This trial tests an online program to help first- and second-year college women resist sexual assault. It aims to empower you with skills and support from peers.
Orlando, FloridaAges 17–24 - NCT06134232RecruitingPhase 2
Extra sipuleucel-T after Provenge for prostate cancer
This trial tests whether adding one extra infusion of sipuleucel-T (the same drug as Provenge) after the standard three doses can help men with advanced prostate cancer that no longer responds to hormone therapy. It is for men who have already finished their three Provenge infusions and have mild or no symptoms.
Tuscon, ArizonaAges 18 years+ - NCT05756322RecruitingPhase 1/Phase 2
Study medicine LBS-007 for relapsed leukemia patients
This trial tests how safe and tolerable LBS-007 is for adults with AML or ALL that has come back or is resistant to treatment. It may help people who can’t use standard therapies or have no proven treatment options.
Tampa, FloridaAges 18–120
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,200 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.