Clinical trials
Respiratory Distress clinical trials
Below are recruiting respiratory distress clinical trials, each written for real people, not researchers. We’re tracking 220 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04804943Recruiting
Testing an added breathing therapy for ARDS patients on ventilators
This pilot study tests NOA-001, a treatment given to people with ARDS (a serious lung condition) who are already on a breathing machine. It looks at whether the treatment can improve outcomes in ARDS caused by either non-COVID illnesses or COVID-19.
TokyoAges 16 years+ - NCT05224323Recruiting
Testing a lung opening breathing pattern in early ARDS
This study looks at a specific breathing event (“avalanche phenomenon”) when the lungs are opened in people with early, moderate-to-severe ARDS. The goal is to understand what’s happening in the lungs and whether it can guide better care.
PoitiersAges 18 years+ - NCT05795465RecruitingPhase 2
Study drug for people with acute respiratory distress syndrome
This Phase 2 trial tests GEn-1124 to see if it can improve outcomes in people with acute respiratory distress syndrome (ARDS). You may be eligible if the study drug can be started very soon after ARDS is diagnosed and if you meet the safety and health requirements.
Washington D.C., District of ColumbiaAges 18–85 - NCT05857891Recruiting
Erythropoietin to help clear lung fluid in ARDS
This trial tests whether erythropoietin (EPO), a medicine that affects red blood cell production, can help clear extra fluid from the lungs in people with acute respiratory distress syndrome (ARDS). If it works, it could improve breathing and reduce lung fluid buildup during critical illness.
Wenzhou, ZhejiangAges 18 years+ - NCT06013319RecruitingPhase 3
Esmolol for better oxygen in ARDS patients
This trial tests if esmolol, a heart-slowing drug, can improve oxygen levels in patients with acute respiratory distress syndrome (ARDS) who are on a breathing machine. It may help by adjusting heart rate to a specific range.
Jinan, ShandongAges 18–65 - NCT06014138RecruitingPhase 2/Phase 3
Volatile sedation study for ARDS patients
This trial is comparing a new type of inhaled sedative (volatile sedation) to usual IV sedatives for people with ARDS who are on a ventilator in the ICU. It aims to see if it can help patients breathe better and recover more quickly.
London, LondonAges 17 years+ - NCT06496997RecruitingPhase 2/Phase 3
Steroid treatment for acute lung failure (ARDS) trial
This study tests if adding a type of steroid (glucocorticoid) to standard treatment helps people on a breathing machine recover from severe lung failure (ARDS). It compares different doses to see which works best.
Al FayyumAges Any age - NCT06536543Recruiting
Lung imaging to check over-inflation in ARDS patients lying on their stomach
This trial uses a special lung imaging belt (EIT) to see if the lungs are over-inflated in patients with severe breathing problems (ARDS) when they lie on their stomach. It aims to help doctors adjust ventilator settings for better lung protection.
BayonneAges 18 years+ - NCT06690801Recruiting
Nitric oxide breathing gas for children with lung failure
This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.
Los Angeles, CaliforniaAges birth–21 years - NCT06758492Recruiting
Video vs direct laryngoscopy for surfactant in newborns
This study compares two ways of placing a thin tube into a newborn's windpipe to give surfactant—a medicine that helps their lungs work better. It will help doctors understand which method is safer and easier for babies needing this treatment.
RijekaAges birth–4 weeks - NCT06814340RecruitingPhase 3
CPAP on ECMO for severe lung failure
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
BobignyAges 18 years+ - NCT07208591RecruitingPhase 3
Test of an experimental drug for severe viral lung infection (ARDS)
This study tests an experimental drug (STSA-1002) for people with severe breathing problems caused by a viral infection. It aims to see if the drug can help improve oxygen levels and reduce the need for a breathing machine.
Beijing, Beijing MunicipalityAges 18–85 - NCT07251790Recruiting
Better breathing support for very preterm babies
This trial tests different ways to help very preterm babies when they are first taken off a breathing machine and switched to CPAP. It aims to find the safest and most effective breathing support to help them breathe on their own.
Melbourne, VictoriaAges birth+ - NCT07395076Recruiting
Study of immune causes of acute respiratory distress
This trial looks at how the immune system might cause severe breathing problems (ARDS). It may help doctors understand what happens in the lungs during this condition and find better ways to treat it.
ParisAges 18 years+ - NCT07674953Recruiting
CPAP and oxygen delivery in preterm infants
This study looks at how different levels of CPAP (a breathing machine that helps keep the lungs open) affect oxygen delivery and lung expansion in preterm babies. It may help doctors understand the best settings for infants who need breathing support.
Little Rock, ArkansasAges Any age - NCT07413978RecruitingPhase 1/Phase 2
Stem cell injection for severe ARDS
This trial tests whether an injection of stem cells from umbilical cords can help people with severe ARDS (a type of lung failure) recover faster. It is for those who have not improved after standard treatment and whose ARDS is caused by an infection (not COVID-19).
Wuhan, HubeiAges 18–80 - NCT07450846Recruiting
Heart-lung interaction in severe breathing problems
This study looks at how the heart and lungs interact in patients with acute respiratory distress syndrome (a severe lung condition) who are on a breathing machine. Researchers will use ultrasound to check heart function at different times during treatment.
Le Kremlin-BicêtreAges 18 years+ - NCT07317050RecruitingPhase 3
Aprotinin for acute respiratory distress syndrome
This trial tests a drug called aprotinin for people with moderate to severe ARDS who are on a breathing machine. The goal is to see if it helps treat the lung injury.
Ciudad Real, Ciudad RealAges 18 years+ - NCT05947955RecruitingPhase 2
Study drug for infection-related lung failure in adults
This Phase 2 trial tests Rhu-pGSN in adults with acute respiratory distress syndrome (ARDS) caused by an infection. If you qualify, the study may help determine whether the drug improves outcomes in this short-term, life-threatening lung condition.
Los Angeles, CaliforniaAges 18 years+ - NCT06807983Recruiting
Lung and heart ultrasound for breathing trouble in older adults
This trial tests whether using lung and heart ultrasound (LuCUS) can help emergency doctors better diagnose and treat shortness of breath in patients over 65. It aims to improve care for older adults with severe breathing problems.
ToulouseAges 65 years+ - NCT07380373Enrolling by invitation
Testing markers in body fluids for lung injury in children
This study looks at two substances in saliva and lung fluid—called IL-6 and TNF-α—in children with severe lung failure (ARDS) who are on a breathing machine. Measuring these markers may help doctors better understand the condition and guide treatment.
CairoAges 1–10 - NCT07370623Recruiting
AI system to help assess breathing trouble in children
This study is testing an artificial intelligence system that helps doctors evaluate breathing problems in children. It uses a camera and clinical data to see if the AI can make accurate assessments in the emergency room.
Seongnam-si, Gyeonggi-doAges birth–12 years - NCT06554522RecruitingPhase 4
Testing CPAP for Premature Babies with Breathing Problems
This trial tests a breathing support method called CPAP for premature babies with breathing problems in Africa. It may help your baby get better oxygen and avoid more invasive treatments.
BanguiAges 1 hour–1 day - NCT06720818Recruiting
Infection-fighting cells in severe lung injury
This study looks at a type of immune cell (MAIT cell) in patients with severe lung problems caused by infections, pancreatitis, head injury, burns, or major surgery. It aims to understand how these cells change during illness, which may lead to better treatments.
ToursAges 18 years+
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Common questions
- Are there clinical trials for respiratory distress?
- Yes. Clin2 currently lists 220 recruiting respiratory distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.