Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 396 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07169695RecruitingPhase 2
Comparing a new eye drop to cyclosporine for eye allergy in kids
This study tests a new eye drop (T1695) against cyclosporine for children with moderate to severe vernal keratoconjunctivitis, a type of eye allergy. It aims to see which treatment works better and is safer for reducing symptoms.
Kolkata, West BengalAges 4–17 - NCT07187297Recruiting
Radiofrequency skin tightening study for loose skin and wrinkles
This study tests a radiofrequency device called Thermage® FLX to see how well it tightens skin and reduces wrinkles on the neck, face, belly, or upper arms. It may be a good option if you have mild to moderate skin looseness or lines and haven't had recent cosmetic procedures.
New York, New YorkAges 30–60 - NCT07197164RecruitingPhase 2
Remdesivir for kidney transplant patients with mild COVID-19
This trial tests whether giving remdesivir to kidney transplant patients who test positive for COVID-19 can prevent them from getting severely ill. It is for people who have already had at least three COVID-19 vaccine doses and are scheduled to receive a kidney transplant soon.
Badalona, BarcelonaAges 18 years+ - NCT07215754Recruiting
Real-world study of anifrolumab for active lupus
This study tracks how well anifrolumab works and how safe it is for people with active lupus. It's a real-world look at the drug's effects, so no additional treatments or tests are required beyond what your doctor already prescribes.
PisaAges 18 years+ - NCT07219407RecruitingPhase 2
Long-term safety study of RAP-219 for focal seizures
This study tests the long-term safety and effectiveness of RAP-219, an investigative medication for focal epilepsy. It is for people who already completed an earlier study of RAP-219, have a type of epilepsy that doesn't respond to standard medicines, and use a surgically implanted brain device (RNS system) to help manage seizures.
Boise, IdahoAges 18–70 - NCT07220876Recruiting
VisiPlate implant for hard-to-control open-angle glaucoma
This trial tests a new device called VisiPlate that is placed in the eye to help lower pressure for people with hard-to-control open-angle glaucoma. It may be an option if standard treatments haven't worked well enough.
Glendale, ArizonaAges 45 years+ - NCT07229430Recruiting
Ultrasound treatment for loose neck and chin skin
This study tests a high-intensity focused ultrasound (HIFU) device to lift and tighten loose skin under the chin and neck. If you are in good health and want a non-surgical option for mild to moderate skin laxity, this trial may be for you.
Los Angeles, CaliforniaAges 30–65 - NCT07233473Recruiting
Vaginal gel for preventing repeat urinary tract infections
This trial tests a vaginal gel to see if it can prevent frequent urinary tract infections (UTIs) in women. It may help if you have had at least 4 UTIs in the past year or 2 in the past 6 months.
VilleurbanneAges 18–84 - NCT07261826Recruiting
Long-term effects of fecal microbiota transplant
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
Shanghai, Shanghai MunicipalityAges 3 years+ - NCT07271342Recruiting
Tracking tenecteplase for stroke in real-world settings
This study is collecting information on stroke patients who received the clot-dissolving drug tenecteplase. It aims to see how well the drug works and how safe it is in everyday hospital care in China.
BeijingAges 18 years+ - NCT07280247Recruiting
AlphaVac System for Treating Acute Pulmonary Embolism
This study tests a device that suctions blood clots from the lungs in people with a moderate-risk pulmonary embolism. The goal is to see if it is safe and effective at removing clots and improving blood flow.
Saint Cloud, MinnesotaAges 18 years+ - NCT07284121Recruiting
Patient satisfaction and safety of Atezolizumab in routine care
This study tracks how well Atezolizumab (Tecentriq) works for people with certain lung or liver cancers in everyday medical practice. It helps doctors understand if patients are satisfied with their treatment and how it affects their quality of life.
KremsAges 18 years+ - NCT07296497Recruiting
Acupuncture for stubborn rosacea: safety and effectiveness
This trial tests whether acupuncture can help people with rosacea that hasn't improved with standard treatments like oral antibiotics or light therapy. If you have persistent redness or flushing that affects your daily life, this study may offer a new option.
Changsha, HunanAges 18–65 - NCT07298811RecruitingPhase 1/Phase 2
Healthy eye bacteria for dry eye treatment
This study tests whether putting healthy bacteria from a family member's eye surface onto your eyes can help treat moderate to severe dry eye. You would receive standard dry eye drops plus the experimental transplant.
Nanchang, JiangxiAges 18–70 - NCT07309822Recruiting
Beltaven® venom allergy immunotherapy study
This study tests a treatment called Beltaven® for people with severe allergic reactions to bee, wasp, or hornet stings. It aims to see if the treatment is safe and helps prevent future reactions.
Barcelona, BarcelonaAges 14 years+ - NCT07323342Recruiting
Hyaluronic acid plus fibrinogen for knee arthritis
This study tests whether a combination of two natural substances—hyaluronic acid (a joint lubricant) and fibrinogen (a blood protein that helps healing)—given as an injection into the knee, can safely reduce pain and improve function in people with knee osteoarthritis. It is for Vietnamese patients who have not recently used certain painkillers or had other knee treatments.
Ho Chi Minh CityAges 45–75 - NCT07678268RecruitingPhase 4
Comparing HIV treatments for virologically suppressed men
This trial tests if a two-drug HIV regimen (darunavir/cobicistat plus lamivudine) works as well as a three-drug regimen (darunavir/cobicistat plus tenofovir alafenamide/emtricitabine) in men whose HIV is already suppressed. The goal is to find a simpler, effective option that may have fewer side effects.
Mexico City, Mexico CityAges 18 years+ - NCT05954910Recruiting
Study of polatuzumab for real-world DLBCL patients in China
This study looks at how well a drug called polatuzumab works for people with a type of lymphoma (DLBCL) in everyday medical practice in China. It is for patients who are older, have other health problems, or whose lymphoma came back after or did not respond to treatment.
BeijingAges 18 years+ - NCT07677696Recruiting
Study of midline catheters for first-time placement
This trial is testing how well a midline catheter works for people who need one for the first time. It will help doctors understand if this type of IV line is a good option for delivering medication or fluids.
ZiboAges 18 years+ - NCT07598422Recruiting
Safety and Effectiveness of Canakinumab for Schnitzler's Syndrome
This study tracks how well and safely canakinumab (a medication that reduces inflammation) works in patients newly diagnosed with Schnitzler's syndrome. Schnitzler's syndrome is a rare condition causing recurring fevers, rashes, and joint pain, and this study helps doctors understand how this drug performs in real-world use.
Kanoya, Kagoshima-kenAges birth+ - NCT07367100Recruiting
Testing a new clot-removal catheter for stroke
This study tests a special catheter (a thin tube) designed to remove blood clots from large arteries in the brain during a stroke. The goal is to see if it is safe and effective at restoring blood flow.
EdegemAges 18–90 - NCT07376590Recruiting
Flow diverter stent study for brain aneurysms
This trial tests a flow-diverting stent for treating certain brain aneurysms located in distal parts of the brain's arteries. It’s for people who have already received this stent and are between 18 and 80 years old.
Hangzhou, ZhejiangAges 18–80 - NCT01604395Recruiting
Long-term growth hormone check for children with short stature
This study follows children who are short for their age and checks how safe and effective growth hormone is over the long term. It may help families understand expected benefits and side effects for their specific growth-related condition.
SeoulAges 2 years+ - NCT07675070Recruiting
Temozolomide (Amitzo) for grade III or IV brain tumors
This trial studies a new form of the chemotherapy drug temozolomide (called Amitzo) in people with aggressive brain tumors (grade III or IV gliomas). It aims to see if the drug is safe and effective, and is for patients who need treatment for a new diagnosis or for tumors that have come back after standard care.
TehranAges 18–80
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 396 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.