Clinical trials
Seizures clinical trials
Below are recruiting seizures clinical trials, each written for real people, not researchers. We’re tracking 104 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07234695RecruitingPhase 3
Levetiracetam to prevent seizures in adults with Down syndrome and Alzheimer's
This trial tests if levetiracetam, a seizure medication, can prevent seizures in adults with Down syndrome who also have Alzheimer's disease. It aims to help manage a common complication and improve quality of life.
Granada, AndalusiaAges 40 years+ - NCT07239115RecruitingPhase 3
Levetiracetam to prevent seizures after brain tumor surgery
This trial tests whether the drug levetiracetam can prevent seizures in people who have brain tumor surgery. If you are having surgery to remove a brain tumor and have never had a seizure, this study may help keep you from having one after the operation.
BeijingAges 18–75 - NCT06908356RecruitingPhase 2
Testing PRAX-628 for focal or tonic-clonic seizures
This study tests an experimental pill called PRAX-628 for adults whose seizures are not fully controlled by current medications. It aims to see if the drug is safe and effective at reducing seizures.
Phoenix, ArizonaAges 18–75 - NCT07141329RecruitingPhase 2
Long-term study of SPN-817 for focal seizures
This study gives SPN-817 to people who completed a prior study of the same drug, to see if it stays safe and works well over a longer time. You may qualify if you already finished that study and have stable seizure medicine.
Port Charlotte, FloridaAges 18 years+ - NCT07136298Recruiting
Spotting seizures in the ICU
This study looks at how well different healthcare professionals can identify seizures in intensive care unit (ICU) patients. It aims to improve seizure detection and care.
Nottingham, NottinghamshireAges Any age - NCT07116330Recruiting
Seizures starting after 50: testing heart and blood vessel risk
This study looks at whether checking and treating heart and blood vessel risk factors can help people who start having seizures after age 50. It includes two parts: one that adds a risk check to your regular care, and one that uses your medical records to learn more about this condition.
BoråsAges 50 years+ - NCT07098728Recruiting
Levetiracetam vs Phenobarbital for prolonged seizures in children
This trial compares two antiseizure medicines, levetiracetam and phenobarbital, to see which one works better for children whose prolonged seizures (lasting several minutes) do not stop after two doses of a rescue medicine called benzodiazepine.
Yangon, YangonAges 1 month–12 years - NCT07072624RecruitingPhase 4
Preventing seizures after severe head injury
This trial tests whether giving medication right after a serious head injury can prevent early seizures. It may help people with certain types of brain injuries seen on CT scans.
Chandigarh, PunjabAges 18–70 - NCT07059325RecruitingEarly Phase 1
Quick brain stimulation for seizures caused by stress or emotional distress
This trial tests if a fast form of brain stimulation (TMS) can reduce seizures that are caused by stress or emotional triggers — not epilepsy. It's for people who have been diagnosed with functional seizures and have not gotten better with talk therapy alone.
Charleston, South CarolinaAges 18–65 - NCT06798896RecruitingPhase 2
SPN-817 for hard-to-control focal seizures
This study tests an investigational drug called SPN-817 to see if it can reduce focal seizures (seizures that start in one area of the brain) in adults whose seizures are not well controlled by current medications.
Phoenix, ArizonaAges 18–70 - NCT05219617RecruitingPhase 3
Carisbamate for frequent drop seizures in Lennox-Gastaut
This Phase 3 study tests whether carisbamate can reduce drop seizures in people with Lennox-Gastaut syndrome (LGS). It also checks whether the treatment is safe when added to existing seizure medicines.
Palo Alto, CaliforniaAges 4–55 - NCT06672588Recruiting
Magnetic seizure therapy for schizophrenia
This trial tests a new type of brain stimulation called magnetic seizure therapy (MST) for people with schizophrenia who haven't gotten better with standard medicines. The goal is to see if MST can help reduce symptoms like hallucinations or confusion.
Vancouver, British ColumbiaAges 18 years+ - NCT06598189Recruiting
Ear-seizure detection study for epilepsy monitoring
This study tests a wearable ear device that may help detect seizures during your stay in the Epilepsy Monitoring Unit. It aims to see if the device can work alongside standard monitoring to improve seizure detection.
Worcester, MassachusettsAges 18 years+ - NCT06581302Recruiting
Magnetic seizure therapy for psychotic disorders
This trial tests magnetic seizure therapy (MST) as a treatment for people with schizophrenia or other psychotic disorders. It aims to see if MST can help reduce symptoms like hallucinations or delusions.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT06529029RecruitingPhase 2/Phase 3
Comparing new low-pulse ECT to standard ECT for depression
This trial tests a new type of seizure therapy (low amplitude pulse seizure therapy) against the standard ultra-brief right unilateral ECT for people with severe depression, including those with suicidal thoughts. The goal is to see which treatment works better.
Grand Rapids, MichiganAges 18–90 - NCT02552511Recruiting
Study of seizures in newborns and how often they occur
This study looks at newborns (up to 28 days old) who have seizures to understand them better, using EEG brain-wave testing. If you agree to participate and can follow the study plan, your child’s information may help researchers learn more about neonatal seizures.
Shanghai, Shanghai MunicipalityAges Up to 4 weeks - NCT05851391RecruitingPhase 2
Test drug treatment to stop hard-to-control seizures after cardiac arrest
This Phase 2 trial tests a medication strategy to stop “refractory status epilepticus,” a severe seizure condition that can happen after a cardiac arrest. It may help by reducing ongoing seizure activity after return of circulation in the ICU.
San Francisco, CaliforniaAges 18 years+ - NCT05819268Recruiting
Mind and body program by telehealth for functional seizures
This trial tests whether a “retraining and control” mind-body program delivered online can help reduce symptoms of functional seizures in teens. It’s mainly a feasibility study, meaning it checks if the program can be done safely and in a way that works for families.
Birmingham, AlabamaAges 11–18 - NCT04080778Recruiting
Magnetic seizure treatment for severe bipolar or hard-to-treat depression
This trial studies whether a seizure-like therapy using magnet stimulation can quickly reduce severe depressive symptoms in people with bipolar depression or treatment-resistant depression. It may help when depression is intense and hasn’t improved enough with at least two antidepressant medicines.
Houston, TexasAges 22–85 - NCT05716100RecruitingPhase 3
Study drug for focal epilepsy that isn’t controlled on current meds
This trial tests XEN1101 compared with a placebo (inactive pill) in people with focal-onset seizures that haven’t been fully controlled despite trying at least two anti-seizure medicines. If you qualify, you may help researchers see whether the study drug reduces seizure frequency and improves control.
Little Rock, ArkansasAges 18 years+ - NCT05667142RecruitingPhase 3
Testing an add-on drug for hard-to-control generalized convulsive seizures
This Phase 3 trial tests XEN1101 added to your current seizure medicines for people with primary generalized tonic-clonic seizures. It’s for seizures that have not fully stopped even after trying at least two appropriate medicines.
Mobile, AlabamaAges 12 years+ - NCT05076617Enrolling by invitationPhase 3
Testing a long-acting rescue seizure medicine for prolonged seizures
This Phase 3 study tests the safety and side effects of Staccato alprazolam for teens and adults (12+) who have certain types of long-lasting seizures. It may help people by offering a specific medicine option aimed at stopping prolonged seizure episodes under close medical study.
Phoenix, ArizonaAges 12 years+ - NCT05077904RecruitingPhase 3
Staccato alprazolam study for prolonged seizures in teens and adults
This Phase 3 trial tests whether staccato alprazolam can reduce and manage “prolonged seizures” that happen repeatedly in people with epilepsy. It also checks safety—especially breathing and heart-related side effects—while participants continue their usual seizure medicines.
Phoenix, ArizonaAges 12 years+ - NCT03419260Recruiting
Continuous EEG monitoring in critically ill children
This study looks at whether continuous brain-wave monitoring can guide seizure care in sick children in the pediatric intensive care unit. It also studies how this approach may affect children’s thinking and behavior later.
Philadelphia, PennsylvaniaAges 1 month–18 years
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Common questions
- Are there clinical trials for seizures?
- Yes. Clin2 currently lists 104 recruiting seizures studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a seizures trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a seizures trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.