Clinical trials
Soft Tissue Infections clinical trials
Below are recruiting soft tissue infections clinical trials, each written for real people, not researchers. We’re tracking 131 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06263231RecruitingPhase 3
Study of INT230-6 injection for soft tissue sarcoma
This study tests an experimental drug, INT230-6, injected directly into tumors, compared to the usual treatments for soft tissue sarcoma. It aims to see if the injection is safe and works better for people whose cancer has not responded to earlier treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT05182164RecruitingPhase 2
Pembrolizumab plus cabozantinib for advanced sarcoma patients
This Phase 2 trial studies whether combining pembrolizumab and cabozantinib can control advanced sarcoma that can’t be removed by surgery and has grown or returned after standard treatment. It may help shrink tumors and improve outcomes in adults who have limited treatment options left.
BordeauxAges 18 years+ - NCT07291297RecruitingPhase 2
Metformin plus standard therapy for soft tissue sarcoma
This trial tests adding metformin, a common diabetes drug, to the usual first cancer treatment for advanced soft tissue sarcoma. It may help the standard therapy work better.
Charlotte, North CarolinaAges 18 years+ - NCT05839275RecruitingPhase 1/Phase 2
Radiation plus two medicines for high-risk soft tissue sarcoma
This Phase 1/2 trial tests whether combining radiation with two targeted/immune medicines can shrink or control high-risk soft tissue sarcoma and improve outcomes. It may help patients whose tumors are large, hard to fully remove, or have come back after prior treatment.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05774275RecruitingPhase 1/Phase 2
Testing combined radiation, chemotherapy, and immunotherapy for high-risk sarcoma
This study tests whether giving radiation, chemotherapy, and immunotherapy together can control high-risk soft tissue sarcoma that is hard to remove or may come back after surgery. It may help by attacking cancer in different ways, including boosting the immune system.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07734337Enrolling by invitation
Reconstruction surgery for upper body soft tissue defects
This trial tests a surgical technique using a skin flap from the back (called a TDAP flap) to repair defects in the upper body, such as after cancer surgery, injury, or scar release. It may help patients who need reconstructive surgery on the breast, shoulder, chest wall, or armpit.
Sohag, Sohag GovernorateAges 5–75 - NCT03805022RecruitingPhase 3
Extra chemotherapy around surgery for high-risk soft-tissue sarcoma
This trial tests whether giving stronger chemotherapy before and/or after surgery helps people with high-risk, resectable soft-tissue sarcoma. It aims to lower the chance the cancer comes back by improving treatment around the time of the operation.
BordeauxAges 18 years+ - NCT06835049RecruitingPhase 2
Heating therapy before surgery for high-risk soft tissue sarcoma
This trial tests a new approach for high-risk soft tissue sarcoma of the arm, leg, or trunk. Before surgery, you would receive chemotherapy combined with local hyperthermia (a treatment that gently heats the tumor area) to see if this can improve outcomes.
AarauAges 18 years+ - NCT06848582Recruiting
NK cell therapy for high-risk pediatric soft tissue sarcoma
This trial tests whether giving immune cells called NK cells from donated umbilical cord blood can help children and teens with high-risk or returning soft tissue sarcoma. The goal is to see if it is safe and effective when other treatments have been tried.
Guangzhou, GuangdongAges Up to 18 years - NCT02275286RecruitingPhase 1/Phase 2
Trabectedin plus radiation for select soft tissue sarcomas
This trial studies whether adding a chemotherapy medicine called trabectedin to targeted radiation can help control certain soft tissue sarcomas. It focuses on specific cancer types and locations, aiming to shrink tumors while keeping radiation safe for nearby healthy organs.
BordeauxAges 18 years+ - NCT06474676RecruitingPhase 1
Modified immune cell therapy for advanced sarcoma
This trial tests a new treatment using your own immune cells (TILs) that have been modified to attack sarcoma tumors. It is for people with advanced soft tissue or bone sarcoma who have already tried at least one other therapy.
Houston, TexasAges 12 years+ - NCT05333458RecruitingPhase 2
Atezolizumab plus selinexor for advanced alveolar soft tissue sarcoma
This Phase 2 trial tests whether combining atezolizumab with selinexor can slow or shrink advanced alveolar soft part sarcoma (ASPS) in people age 12 and older. It may help by improving the immune system’s ability to fight the cancer and stopping cancer cell growth signals.
Los Angeles, CaliforniaAges 12 years+ - NCT05614375Recruiting
Endoscopic surgery for soft tissue cancer in the nose
This trial studies using a minimally invasive camera-assisted surgery to remove soft tissue sarcoma in the nose and nearby sinuses. It may help by aiming to fully remove the tumor safely while considering how well patients’ bodies can handle surgery.
Shanghai, Shanghai MunicipalityAges Any age - NCT07283731RecruitingPhase 2
Testing zanzalintinib plus pembrolizumab for certain sarcomas
This trial is looking at whether a new combination of two drugs, zanzalintinib and pembrolizumab, can help people with certain types of advanced soft-tissue sarcoma that have not responded to other treatments. It aims to find out if the combination is safe and effective.
Houston, TexasAges 18 years+ - NCT05440240RecruitingPhase 4
Needling and possibly steroid shot for Dupuytren’s hand tightness
This trial tests a minimally invasive procedure that uses a needle to release tight tissue in the hand, and may include a steroid injection. It aims to improve hand finger straightening for people with Dupuytren’s contracture.
SilkeborgAges 45–99 - NCT06422806RecruitingPhase 3
Immunotherapy plus chemo for aggressive sarcoma
This trial compares a combination of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) versus chemotherapy alone for people with aggressive, poorly differentiated sarcomas that have spread or cannot be removed. The goal is to see if adding immunotherapy helps shrink tumors or slow their growth better than chemotherapy alone.
Phoenix, ArizonaAges 18 years+ - NCT04330456Recruiting
Radiation plus surgery for first soft tissue sarcoma
This trial studies a treatment plan for newly diagnosed soft tissue sarcoma that combines precisely targeted radiation before surgery and conformal radiation after surgery. It may help by improving tumor control while allowing the surgeon to remove the tumor safely.
Saint PetersburgAges 18–75 - NCT04040205RecruitingPhase 2
Abemaciclib for sarcoma with specific cell-growth gene changes
This trial tests abemaciclib (a cancer medicine) in adults with advanced, unresectable bone or soft-tissue sarcoma that has certain gene changes in the “CDK pathway.” It aims to shrink tumors or slow growth in people whose tumors match the study’s biomarker and lab requirements.
Jacksonville, FloridaAges 18 years+ - NCT06354374Recruiting
Classifying jawbone shape for better dental implants
This study looks at how the shape and thickness of your gum and jawbone affect dental implant success. It uses a 3D scan (CBCT) to classify the bone, which may help doctors choose the best treatment for missing teeth.
Al Shorouk City, Cairo GovernorateAges 18 years+ - NCT06308419RecruitingPhase 1
Combination gemcitabine and nab-sirolimus for advanced sarcoma
This trial tests a combination of two drugs—gemcitabine (a chemotherapy drug) and nab-sirolimus (a targeted therapy)—for people with advanced soft-tissue sarcoma or leiomyosarcoma, especially those whose tumors have a specific genetic change in the TSC2 or TSC1 genes. The goal is to see if this combination can shrink tumors or slow their growth.
Houston, TexasAges 18 years+ - NCT07260630Enrolling by invitation
Hamstring tightness relief study
This trial tests different massage-type techniques to see which helps tight hamstrings best. If you are between 18 and 30 and have stiff hamstrings, this may help find a quick, drug-free solution.
Ankara, AnkaraAges 18–30 - NCT07714031Recruiting
Wrist Release Therapy for Overuse Syndrome
This study tests a special hands-on therapy technique for people with wrist pain from overuse, like computer workers. It may help improve movement and reduce pain without surgery.
Faisalabad, Punjab ProvinceAges 20–50 - NCT07070245Enrolling by invitation
Comparing two therapies for plantar fasciitis pain
This study compares two hands-on treatments for plantar fasciitis: a technique using tools to massage the tissue and a method that involves holding the foot in a specific position. It aims to see which better reduces heel pain and improves movement.
Port Said, Port Said GovernorateAges 30–50 - NCT07066982RecruitingPhase 1/Phase 2
CAR T cells targeting CD146 and HER2 for advanced sarcomas
This trial tests a new type of immunotherapy where your own immune cells are modified to find and attack sarcoma cells that carry markers called CD146 or HER2. It is for people with advanced sarcoma who have already tried standard treatments.
Beijing, Beijing MunicipalityAges 21–90
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Common questions
- Are there clinical trials for soft tissue infections?
- Yes. Clin2 currently lists 131 recruiting soft tissue infections studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a soft tissue infections trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a soft tissue infections trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.