Clinical trials
Soft Tissue clinical trials
Below are recruiting soft tissue clinical trials, each written for real people, not researchers. We’re tracking 294 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07714265Recruiting
Gum thickening around dental implants: comparing three methods
This trial compares three techniques to thicken gum tissue around a single dental implant in the back of the lower jaw. It may help if you have thin gums and need a dental implant.
CairoAges 20 years+ - NCT05333458RecruitingPhase 2
Atezolizumab plus selinexor for advanced alveolar soft tissue sarcoma
This Phase 2 trial tests whether combining atezolizumab with selinexor can slow or shrink advanced alveolar soft part sarcoma (ASPS) in people age 12 and older. It may help by improving the immune system’s ability to fight the cancer and stopping cancer cell growth signals.
Los Angeles, CaliforniaAges 12 years+ - NCT05537545Recruiting
Timing of gum tissue graft after a new tooth implant
This trial studies the best timing for placing a gum (soft tissue) graft after getting an implant right away when a tooth is removed. It may help improve healing and the long-term appearance and stability of the implant.
Ghent, Oost-VlaanderenAges 20 years+ - NCT07283731RecruitingPhase 2
Testing zanzalintinib plus pembrolizumab for certain sarcomas
This trial is looking at whether a new combination of two drugs, zanzalintinib and pembrolizumab, can help people with certain types of advanced soft-tissue sarcoma that have not responded to other treatments. It aims to find out if the combination is safe and effective.
Houston, TexasAges 18 years+ - NCT04219202Recruiting
Pre-surgery radiation for retroperitoneal soft tissue cancer
This study tests giving special radiation (ions) before surgery for a specific cancer in the back of the abdomen (retroperitoneal soft tissue sarcoma). The goal is to shrink or control the tumor so surgery may be safer or more effective.
HeidelbergAges 18 years+ - NCT05729607Recruiting
Gum tissue repair around an implant using two material types
This trial compares two ways of adding gum (soft tissue) around a dental implant—using donor gum tissue versus a different graft material. If you have a healthy implant with some gum recession, this study may help find which approach works better for healing and gum coverage.
Boston, MassachusettsAges 18–99 - NCT03889899Recruiting
Device treatment for certain skin, mouth, or surface soft tissue cancers
This trial studies a radiation-emitting device (DaRT) to treat certain cancers on the skin, in the mouth, or in superficial soft tissues. You may qualify if you have a confirmed malignant tumor, enough body strength for treatment, and blood tests and pregnancy status that meet safety limits.
HaifaAges 18 years+ - NCT04534127Recruiting
DaRT radiation device for skin and mouth or superficial tumors
This trial tests a targeted radiation device (DaRT seeds) to treat certain cancers on the skin, in the mouth, or in superficial soft tissue. It may help when standard treatment (like surgery or regular radiation/chemo) hasn’t worked, isn’t safe, or isn’t wanted.
JerusalemAges 18 years+ - NCT05440240RecruitingPhase 4
Needling and possibly steroid shot for Dupuytren’s hand tightness
This trial tests a minimally invasive procedure that uses a needle to release tight tissue in the hand, and may include a steroid injection. It aims to improve hand finger straightening for people with Dupuytren’s contracture.
SilkeborgAges 45–99 - NCT07489014Enrolling by invitation
Therapy techniques for neck pain relief
This trial tests two hands-on treatments—gentle joint movement and soft tissue release—to see which better helps long-lasting neck pain. It could offer pain relief without surgery or strong medications.
IstanbulAges 18–65 - NCT06422806RecruitingPhase 3
Immunotherapy plus chemo for aggressive sarcoma
This trial compares a combination of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) versus chemotherapy alone for people with aggressive, poorly differentiated sarcomas that have spread or cannot be removed. The goal is to see if adding immunotherapy helps shrink tumors or slow their growth better than chemotherapy alone.
Phoenix, ArizonaAges 18 years+ - NCT06571734RecruitingPhase 2
Zanzalintinib for advanced sarcomas
This trial tests a new targeted therapy pill (XL092, also called zanzalintinib) for people with certain advanced sarcomas that have not responded to other treatments. The goal is to see if the drug shrinks tumors or slows their growth.
Chicago, IllinoisAges 18 years+ - NCT07368621Recruiting
Gum graft with or without platelet-rich fibrin for dental implant thickness
This trial tests if adding a special blood concentrate (platelet-rich fibrin) to a standard gum graft helps thicken the gum tissue around a dental implant. It is for people with thin gums who are missing a single tooth.
Cairo, Cairo GovernorateAges 18–60 - NCT04330456Recruiting
Radiation plus surgery for first soft tissue sarcoma
This trial studies a treatment plan for newly diagnosed soft tissue sarcoma that combines precisely targeted radiation before surgery and conformal radiation after surgery. It may help by improving tumor control while allowing the surgeon to remove the tumor safely.
Saint PetersburgAges 18–75 - NCT06873685Recruiting
Soft tissue sarcoma: surgery, rehab, and nutrition study
This trial is for people with a newly diagnosed soft tissue sarcoma that has not spread. It will study how surgery, physical therapy, and nutrition affect your recovery and quality of life.
Rome, LazioAges 18 years+ - NCT06857708Recruiting
Wound dressings for necrotizing fasciitis wounds
This study tests two special wound dressings (Cytal® Wound Matrix and MicroMatrix®) to help heal wounds caused by a serious flesh-eating infection called necrotizing fasciitis. The goal is to see if these dressings improve healing and reduce the need for more surgeries.
Cleveland, OhioAges 18 years+ - NCT04040205RecruitingPhase 2
Abemaciclib for sarcoma with specific cell-growth gene changes
This trial tests abemaciclib (a cancer medicine) in adults with advanced, unresectable bone or soft-tissue sarcoma that has certain gene changes in the “CDK pathway.” It aims to shrink tumors or slow growth in people whose tumors match the study’s biomarker and lab requirements.
Jacksonville, FloridaAges 18 years+ - NCT07576192Recruiting
Massage treatments for heel pain in pregnant women
This study compares two hands-on massage techniques to relieve plantar fasciitis (heel pain) in pregnant women during the second trimester. The goal is to find the most effective, safe way to reduce pain without medication.
Lahore, Punjab ProvinceAges 18–40 - NCT07856147Recruiting
Massage and scraping therapy for heel pain
This study compares two non-surgical treatments for plantar fasciitis, a common cause of heel pain. One uses deep friction massage and the other uses a special scraping tool. Both aim to reduce pain and improve function.
Islamabad, Punjab ProvinceAges 19–44 - NCT06751160Recruiting
Dry needling vs. soft tissue massage for tight hamstrings
This study compares two treatments—dry needling and soft tissue massage—to see which works better for relieving tight hamstring muscles in people with low back pain.
Lahore, Punjab ProvinceAges 20–40 - NCT07685340Recruiting
Cupping vs Massage Tool for Chronic Low Back Pain
This trial tests two hands-on therapies—dry cupping and a special massage technique—to see which works better for long-term low back pain caused by muscle knots. You may be able to join if your pain has lasted over 3 months and you have trigger points.
Rawalpindi, Punjab ProvinceAges 25–45 - NCT07090356Recruiting
Soft tissue therapy versus stretching for athletes with piriformis syndrome
This study compares two techniques—instrument-assisted soft tissue mobilization and PNF stretching—to see which works better for reducing pain and improving movement in athletes with piriformis syndrome. It may help if you are an athlete with ongoing buttock or hip pain that makes sitting uncomfortable.
Lahore, Punjab ProvinceAges 18–35 - NCT06981637RecruitingPhase 2
PLD vs. observation for advanced soft tissue sarcoma
This trial tests whether a type of chemotherapy called pegylated liposomal doxorubicin (PLD) can help keep advanced soft tissue sarcoma from growing after successful first treatment with standard anthracycline-based chemo. You may be eligible if you've completed 4-8 cycles of that initial chemo and your disease is controlled (shrank or stable).
Kaohsiung CityAges 18 years+ - NCT07676058Recruiting
Massage vs. tool therapy for heel pain in pregnancy
This trial compares two types of hands-on therapy—myofascial release and instrument-assisted tissue mobilization—to see which works better for pregnant women who have heel pain from plantar fasciitis. It aims to find a safe and effective treatment during pregnancy.
Lahore, Punjab ProvinceAges 20–40
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Common questions
- Are there clinical trials for soft tissue?
- Yes. Clin2 currently lists 294 recruiting soft tissue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a soft tissue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a soft tissue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.