Clinical trials
Spine Surgery clinical trials
Below are recruiting spine surgery clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06785350Recruiting
Smallest effective steroid dose for spine surgery pain
This study tests whether a very small amount of a steroid (betamethasone) placed around the surgical cut can help control pain after spine surgery. It aims to find the lowest dose that still works well, so patients may need fewer painkillers and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–65 - NCT05367609Recruiting
Personalized pain plan for kids getting spine fusion surgery
This trial tests a personalized plan to manage pain around the time of pediatric posterior-lateral spinal fusion surgery. It aims to improve comfort and reduce the chance of pain or opioid problems after surgery by tailoring pain medicines to the child.
San Francisco, CaliforniaAges 10–21 - NCT07326774Recruiting
Ultrasound-guided pain block for back surgery recovery
This trial tests whether a special pain block (Quadro-Iliac Plane Block) given before back surgery can reduce pain after the operation. The goal is to help patients feel more comfortable and need fewer painkillers.
Istanbul, IstanbulAges 18–65 - NCT07611240Recruiting
Comparing two anesthesia types for spine surgery in overweight patients
This study compares two common anesthesia medicines—sevoflurane (inhaled gas) and propofol (IV liquid)—to see which works better for people with obesity having lower-back spine surgery. The goal is to understand which anesthetic is safer and more effective for this group.
ErzurumAges 18–65 - NCT07224451Recruiting
Liquid biopsy during spine surgery with blood-brain barrier disruption
This trial tests a technique called 'barrier disrupting fields' during spine surgery to temporarily open the blood-brain barrier. This may allow doctors to collect a liquid biopsy (a blood test that looks for tumor DNA) to better understand spinal tumors.
Ramat GanAges 18 years+ - NCT07406997Recruiting
Recovery strategies after back surgery
This study tests a program to help people recover better after lumbar spine surgery. You'll learn strategies to improve your recovery and return to daily activities.
Honolulu, HawaiiAges 18–85 - NCT07461636Recruiting
Robotic-assisted screw placement in spine surgery
This trial studies how well a robotic system helps surgeons place screws in the spine. It may help make the surgery more precise and safer.
GothenburgAges Any age - NCT07681648Enrolling by invitationPhase 4
Nerve blocks vs local numbing for lumbar spine surgery
This study compares two types of nerve blocks (a longissimus plane block and a multifidus plane block) to a local numbing injection for pain control during lumbar spine surgery. It aims to find which method works best for patients having back surgery.
Aswān, Aswan GovernorateAges 18–65 - NCT07289737Recruiting
Comparing two spine surgeries for a slipped backbone
This study compares two types of spine surgery for a common condition where a lower back bone slips forward. It aims to see which surgery works better to relieve pain and improve function.
Yiwu, ZhejiangAges 50–90 - NCT04885244Recruiting
Minimally invasive surgery for adult spine bending and misalignment
This trial looks at how well minimally invasive back surgery works for adults with long-lasting spine deformities (like bending or uneven alignment). It aims to measure outcomes using questionnaires and spine X-ray measurements after treatment.
Phoenix, ArizonaAges 18 years+ - NCT06267248Enrolling by invitation
3D scanning to guide spine surgery
This trial tests a 3D scanner that maps your spine during surgery to help the surgeon work more accurately. It is for people already planning spine surgery where the back bones are exposed.
Boston, MassachusettsAges 18–80 - NCT04888104Recruiting
Testing a spine implant to prevent failure near the top
This study looks at whether using a specific attachment system (VersaTie) with pedicle screws can help prevent problems near the top of a long spinal fusion. It compares outcomes in adults who are planning long posterior spine fusion surgery using this approach.
Phoenix, ArizonaAges 18 years+ - NCT07221786Recruiting
Opioid reduction before spine surgery
This trial tests whether slowly reducing opioid pain medications before spine surgery can lead to a better recovery afterward. It is for adults already taking daily opioids who have major spine surgery planned at least a month away.
Philadephia, PennsylvaniaAges 18 years+ - NCT04194138Recruiting
Surgery planning study for complex adult spine curvatures
This trial focuses on adults with complex spinal deformities and tests how different surgical approaches fit their x-ray measurements and surgical plans. It may help doctors choose safer, better-tailored surgery for severe adult spine bending or imbalance.
La Jolla, CaliforniaAges 18 years+ - NCT06857760Recruiting
Soothing methods after spine surgery for nausea and thirst
This study tests three different methods to help reduce nausea, thirst, and discomfort after lower back disc surgery. It compares simple soothing techniques (like cold packs or mouth care) to see which works best for a quicker, more comfortable recovery.
AmasyaAges 18 years+ - NCT07173413Recruiting
Quality of phone check-ins after spine surgery
This study checks how well telephone follow-ups work for patients who had lower back surgery at a Danish hospital. It may help improve future care.
Aalborg, AalborgAges 18 years+ - NCT07180940RecruitingPhase 4
Comparing two medicines added to a nerve block for back surgery
This study compares two medicines (dexamethasone and dexmedetomidine) added to a nerve block for pain control during and after lower back surgery. It aims to see which one works better for reducing pain and the need for other painkillers.
PoznanAges 18 years+ - NCT06202443Recruiting
Physical therapy timing after neck surgery
This study looks at whether starting physical therapy soon after ACDF neck surgery helps people recover better. It compares early physical therapy to standard care.
Honolulu, HawaiiAges 18–75 - NCT05170815Recruiting
Spine Device Registry for Adults Getting Commercial Devices
This study is a registry that collects information about adults who use specific, commercially available spine devices. It may help doctors understand how these devices are used in real-world care and what outcomes look like over time.
LyonAges 18 years+ - NCT05963815Recruiting
Spine surgery follow-up using online patient-reported questionnaires
This study looks at recovery after planned (elective) surgery for common lower-back (“lumbar”) spine problems like slipped discs, disc bulges, and narrowing of the spinal canal. You may be asked to complete online questionnaires, and the study uses your answers to understand symptoms and outcomes after surgery.
Rotterdam, South HollandAges 18–80 - NCT06020508Recruiting
Light device to help place epidural needles
This trial tests a new device that uses light to help doctors place an epidural needle more accurately in your lower back. It may make the procedure safer and more comfortable.
New York, New YorkAges 18–99 - NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT06971835Enrolling by invitation
NanoParticle Matrix spine surgery registry
This study follows people who receive a special bone graft material called NanoParticle Matrix (NPM) during spine surgery. Researchers want to track outcomes over two years to see how well it works.
Baton Rouge, LouisianaAges 18 years+ - NCT06020417Recruiting
Spine screw placement using O-arm navigation
This trial tests whether using a special 3D X-ray navigation system (O-arm) helps place screws more accurately in spine surgery. It may help people with various spine problems who are having spinal fusion.
Teresina, PiauíAges 18 years+
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Common questions
- Are there clinical trials for spine surgery?
- Yes. Clin2 currently lists 91 recruiting spine surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.