Clinical trials
Statin Therapy clinical trials
Below are recruiting statin therapy clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05845424RecruitingPhase 4
High-intensity cholesterol pills for people with silent calcium
This trial studies whether high-intensity statin plus ezetimibe can improve heart health in people who do not have symptoms but have calcium buildup in their heart arteries. It may help lower cholesterol and reduce future heart risks for the right participants.
SeoulAges 40 years+ - NCT06767774RecruitingPhase 4
Comparing two cholesterol treatments for heart patients
This study compares two different ways of lowering cholesterol: a moderate statin (pitavastatin) plus another drug (ezetimibe) versus a stronger statin alone. The goal is to see which approach is safer regarding the risk of developing new diabetes.
SeoulAges 18 years+ - NCT06804980RecruitingPhase 4
Rosuvastatin Tolerance for People with Statin Side Effects
This trial tests a low dose of rosuvastatin (a common statin) in people who have had trouble with statins before. The goal is to see if your body can tolerate this specific dose again, which could help lower your cholesterol without the past side effects.
Minneapolis, MinnesotaAges 21 years+ - NCT05782777Recruiting
Cholesterol medicines after stent: combo pill vs single pill
This trial compares two cholesterol-lowering treatment plans after a heart procedure where new drug-eluting stents were placed: a combination of high-intensity statin plus ezetimibe versus high-intensity statin alone. It may help find which option lowers cholesterol more effectively and safely over the first year after the procedure.
SeoulAges 19 years+ - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT06676280RecruitingPhase 4
Aspirin and statin study for high coronary calcium
This trial tests whether a daily aspirin and a statin medicine can help prevent heart problems in people with high calcium buildup in their heart arteries. It is for people aged 40 to 75 who have a high coronary calcium score (300 or more) and at least one additional risk factor like diabetes or high blood pressure.
AnyangAges 40–75 - NCT07344610Recruiting
Short-term high-dose statin therapy after stroke
This trial tests whether starting a high dose of a statin (a cholesterol-lowering medicine) soon after a stroke can improve your cholesterol levels. It is for people who have had a stroke or have significant narrowing of arteries in the brain or neck.
Shenyang, LiaoningAges 18 years+ - NCT07524101Recruiting
Statin and Ezetimibe for Heart Disease and Kidney Disease
This trial tests whether taking a moderate-strength statin (cholesterol-lowering drug) plus ezetimibe (another cholesterol medicine) together helps protect the heart and kidneys in people who have both chronic kidney disease and established heart disease or stroke history.
SeoulAges 19–85 - NCT07359105Recruiting
Statin vs. LDL Goal Therapy for Older Adults with Diabetes
This trial compares two approaches to lower cholesterol in people aged 70+ with type 2 diabetes: a moderate statin dose versus adjusting treatment to reach a personalized LDL-C target. It aims to find which strategy better prevents heart problems.
SeoulAges 70 years+ - NCT05579626Enrolling by invitationPhase 4
Low-dose statin plus ezetimibe vs high-dose statin for prediabetes
This trial compares two cholesterol-lowering approaches in people with prediabetes to see which one is less likely to lead to new-onset diabetes. It may help you choose a safer medication plan if you need strong cholesterol treatment to prevent future heart problems.
Bucheon-siAges 18–75 - NCT06684106Recruiting
Can a liver medicine protect your blood sugar while on statins?
This study tests if a medicine called ursodeoxycholic acid can help prevent blood sugar rises that statins sometimes cause. It is for people with high cholesterol who have not yet taken a statin, to see if adding this medicine keeps their blood sugar healthy.
Xi'an, ShaanxiAges 18–75 - NCT06902740RecruitingPhase 4
PCSK9 inhibitor with statin for asymptomatic brain artery narrowing
This trial tests whether adding a PCSK9 inhibitor to standard statin therapy can help people with narrowing in brain arteries that hasn't caused symptoms yet. The goal is to see if this combination lowers plaque and prevents future strokes.
Beijing, Beijing MunicipalityAges 18–80 - NCT04735263RecruitingTeam says not enrollingPhase 2
Testing dark vision changes as a statin response signal
This Phase 2 study looks at whether changes in night/dark adaptation can show early whether high-dose atorvastatin (a statin) is helping intermediate age-related macular degeneration (AMD). If you fit, you may help researchers find an earlier way to tell who is responding.
Boston, MassachusettsAges 50–85 - NCT05076019Recruiting
Atorvastatin during heart valve surgery for patients over 60
This trial studies whether taking atorvastatin (a cholesterol medicine) around the time of surgical aortic valve replacement can improve outcomes. It is mainly for people who have not taken similar medicines recently and do not have certain heart rhythm or liver/kidney problems.
OdenseAges 60–95 - NCT05777655Recruiting
Medication app to help people take statins as prescribed
This trial studies whether a medication-management phone app can improve how reliably you take a high-intensity statin (cholesterol-lowering medicine). You may be eligible if you’re starting a statin for blood vessel disease and have higher LDL (“bad cholesterol”) levels.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT05912387RecruitingEarly Phase 1
Testing statin treatment in primary sclerosing cholangitis
This early study looks at how a statin (cholesterol-lowering medicine) affects people with primary sclerosing cholangitis (PSC) by measuring changes using multiple types of health data. It may help researchers understand which people benefit and how PSC biology changes with treatment.
Stanford, CaliforniaAges 18–80 - NCT07460960RecruitingPhase 2
Statin therapy for heart health and erectile function in men
This study tests whether statins, a common cholesterol-lowering medication, can improve erectile function and hormone levels in men at high risk for heart problems. It aims to see if these benefits exist beyond just lowering cholesterol.
MoscowAges 40–65 - NCT06520891Recruiting
Statin with SGLT2i for ischemic heart disease
This study tests if taking a statin along with an SGLT2 inhibitor (a diabetes drug that also helps the heart) works better for people with heart disease caused by blocked arteries. The goal is to improve heart function with this combination therapy.
Al Fayyum, Faiyum GovernorateAges 50–80 - NCT06767345RecruitingPhase 4
Comparing two cholesterol medicines for plaque stabilization
This study compares two ways to lower cholesterol and stabilize artery plaque in people with coronary artery disease who are having a stent procedure. It tests whether a moderate statin plus ezetimibe works as well as a high-intensity statin alone for stabilizing plaque.
Seoul, SeoulAges 18 years+ - NCT06588231Recruiting
Personalized exercise for older adults with heart disease
This study tests whether a personalized exercise program can help older people (60–75) with stable coronary heart disease improve their heart health. You would work with healthcare professionals to get an exercise plan tailored to your condition.
Nanjing, JiangsuAges 60–75 - NCT07742488Recruiting
Statins and hormone therapy for cholesterol in menopause
This study looks at whether taking statins (cholesterol-lowering medicine) along with hormone replacement therapy (HRT) affects blood clotting in women going through menopause who have high cholesterol. It may help doctors understand how these medicines work together.
Pisa, ItalyAges 45–55 - NCT07704918Recruiting
Study: Lowering cholesterol during melanoma immunotherapy
This study tests whether giving aggressive cholesterol-lowering medication to people starting immunotherapy for melanoma can improve heart health. It may help reduce the risk of heart problems during cancer treatment.
Aurora, ColoradoAges 55 years+ - NCT02726555RecruitingPhase 3
Red yeast rice plus low-dose statin versus statin alone
This Phase 3 study compares whether taking red yeast rice plus a low-dose statin works better and is as safe as taking a standard statin alone. It aims to improve cholesterol (especially LDL) and reduce cardiovascular risk in people with mild, confirmed artery disease.
Wenzhou, ZhejiangAges 20–80 - NCT06738758Recruiting
Early intensive cholesterol-lowering study for acute coronary syndrome
This study tests whether starting strong cholesterol-lowering treatment early in the hospital can improve outcomes for people with acute coronary syndrome (a serious heart condition like a heart attack or unstable angina). It may help if you have high LDL cholesterol.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for statin therapy?
- Yes. Clin2 currently lists 25 recruiting statin therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a statin therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a statin therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.