Clinical trials
Stereotactic Body Radiation Therapy (SBRT) clinical trials
Below are recruiting stereotactic body radiation therapy (sbrt) clinical trials, each written for real people, not researchers. We’re tracking 106 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07393867RecruitingPhase 2
PSMA-guided radiation boost for prostate cancer
This trial tests a special type of radiation therapy (SBRT) that delivers a higher dose directly to the main tumor in your prostate, guided by a PSMA PET scan. It aims to improve cancer control while limiting side effects.
Boston, MassachusettsAges 18 years+ - NCT03895359RecruitingPhase 3
Chemo plus targeted radiation versus chemo alone for liver cancer
This trial compares two treatments for liver cancer that can’t be removed with surgery: chemo through the liver (TACE) alone versus TACE plus a precise radiation treatment (SBRT). It may help people whose cancer stays in the liver but can’t be operated on, by testing whether adding focused radiation improves outcomes.
London, OntarioAges 18 years+ - NCT07305428Recruiting
Making large liver tumors removable with immunotherapy and focused radiation
This trial tests a combination of immunotherapy and high-precision radiation (SBRT) to shrink large or multiple liver tumors in people with hepatocellular carcinoma, with the goal of making them small enough for surgery. It's for people who cannot currently have their tumors removed but might become eligible after treatment.
Hong KongAges 18–80 - NCT07299357Recruiting
Radiation therapy for small kidney tumors
This trial tests a precise type of radiation therapy for small, early-stage kidney tumors that cannot be surgically removed or are at high risk for surgery. It aims to offer an alternative treatment with fewer side effects.
Milan, MilanAges 18 years+ - NCT07293468RecruitingPhase 2/Phase 3
Comparing two treatments for advanced liver cancer
This trial tests two different ways to treat liver cancer that can't be removed with surgery. It compares stereotactic body radiation therapy (targeted high-dose radiation) with selective internal radiation therapy (tiny radioactive beads delivered through a blood vessel), both combined with immunotherapy (medicines that help your immune system fight cancer).
Hong KongAges 18–80 - NCT07297004RecruitingPhase 2
Targeted radiation for recurrent rectal cancer
This trial tests targeted radiation (SBRT) for people whose rectal cancer has come back in the pelvis and cannot be surgically removed. The goal is to see if this focused radiation can control the tumor with fewer side effects.
Guangzhou, GuangdongAges 18–75 - NCT07219303Recruiting
Adaptive radiation therapy for intermediate- or high-risk prostate cancer
This trial tests a type of radiation that adjusts to changes in your prostate during treatment. It aims to improve accuracy and reduce side effects for men with intermediate- or high-risk prostate cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07193641RecruitingPhase 2
Lattice radiotherapy with standard care for slow-growing lung cancer
This trial tests whether adding a special radiotherapy technique called lattice radiotherapy to your usual cancer treatment can help control NSCLC that has started to grow in a few new spots. If you have up to 5 growing tumors and at least one measures 4.5 cm or larger, this study might be an option.
Hangzhou, ZhejiangAges 18 years+ - NCT05903261Recruiting
Study of targeted radiation for rare cancers with limited spread
This observational study follows people with rare solid tumors and a limited number of metastases treated with a focused radiation technique (SBRT). Doctors want to see outcomes after using a strong, curative-intent radiation dose to all active spots.
Rozzano, MilanAges 18 years+ - NCT07142967Recruiting
MR-Linac radiotherapy for prostate cancer that returned after earlier radiation
This trial tests if a special MRI-guided radiotherapy machine (MR-Linac) can safely treat prostate cancer that has come back after previous radiation therapy. It may help men who have limited options and want to avoid more invasive treatments.
New York, New YorkAges 18 years+ - NCT07128355RecruitingEarly Phase 1
Combined immunotherapy and radiation for colorectal cancer
This trial tests the combination of two immunotherapy drugs (botensilimab and balstilimab) plus targeted radiation to liver tumors. It's for people with colorectal cancer that has spread and hasn't responded to standard treatments.
Boston, MassachusettsAges 18 years+ - NCT07121335Recruiting
SABR for limited metastatic cancer
This trial tests a precise, high-dose radiation treatment (SABR) for people whose cancer has spread to a few spots (up to 5) and is not growing in the brain or been previously treated with radiation in those same spots.
SeoulAges 18 years+ - NCT07112170Recruiting
Radiation to slow melanoma growth after initial treatment
This study tests whether giving precise radiation to a limited number of growing spots can help control melanoma that has spread but is otherwise stable on immunotherapy or targeted therapy. You may join if you have up to 10 growing spots outside the brain that can be safely treated with focused radiation.
Toronto, OntarioAges 18 years+ - NCT07101679RecruitingPhase 2
Study of radiation, chemo, and immunotherapy for advanced pancreatic cancer
This trial tests a combination of chemotherapy (GnP), an immunotherapy drug (serplulimab), and targeted radiation (SBRT) as a first treatment for locally advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this triple therapy can shrink the tumor and improve outcomes.
Chengdu, SichuanAges 18–75 - NCT05071105Recruiting
Short-course radiation for early breast cancer in older women
This study looks at a brief type of radiation called SBRT given soon after starting hormone therapy for certain early breast cancers in women age 75 and older. It may help treat the cancer locally while aiming to be easier to receive than longer radiation schedules.
Rome, RomeAges 75 years+ - NCT06987890Recruiting
Geriatric assessment for older adults with lung cancer getting SBRT
This study looks at how a geriatric assessment can help older adults with early-stage lung cancer who are getting a precise type of radiation therapy called SBRT. The goal is to understand their needs and improve care.
Boston, MassachusettsAges 65 years+ - NCT06927635RecruitingPhase 2
SBRT vs standard care for prostate cancer that has spread to a few spots
This trial tests whether targeted radiation (SBRT) to a few sites of cancer spread can help men whose prostate cancer has stopped responding to hormone therapy but has not spread to many places. You may benefit if you have a limited number of growing spots outside the brain or spine.
Toronto, OntarioAges 18–100 - NCT06914440RecruitingPhase 2
Radiation and immunotherapy before surgery for HR+/HER2- breast cancer
This trial is testing a new treatment approach for patients with a certain type of breast cancer (HR+/HER2-). It combines radiation therapy with chemotherapy and an immunotherapy drug before the patient's main surgery, to see if it can shrink or eliminate the tumor more effectively.
Xi'an, Shannxi ProvinceAges 18–75 - NCT04004312Recruiting
Short-course radiation slices for localized prostate cancer
This trial tests a radiation approach that delivers treatment in a small number of larger “fractions” (short-course SBRT) for prostate cancer. It may help by targeting the prostate while shortening the overall number of visits.
Montreal, QuebecAges 18 years+ - NCT06885879Recruiting
Studying ctDNA changes after radiation for liver cancer
This trial studies how radiation therapy (SBRT) affects a DNA fragment in the blood called ctDNA in people with liver cancer. By tracking ctDNA changes, doctors hope to better understand how well the treatment is working and possibly predict outcomes earlier.
Hong KongAges 18 years+ - NCT06877299RecruitingPhase 2
Combination Therapy for Stage IIA-IIIB Lung Cancer
This trial tests a combination of low-dose radiation, focused high-dose radiation (SBRT), chemotherapy, and an immunotherapy drug (tislelizumab) for people with stage IIA to IIIB non-small cell lung cancer that hasn't been treated yet. The goal is to see if this approach can help shrink tumors and improve outcomes before or instead of surgery.
Chengdu, ChinaAges 18–75 - NCT06835725RecruitingPhase 2
Comparing two prostate radiation schedules for intermediate risk
This trial compares giving radiation in 2 treatments versus 5 treatments for prostate cancer that hasn't spread. It's for men with low or intermediate risk prostate cancer who are healthy enough to undergo a short course of targeted radiation.
Surrey, British ColumbiaAges 18 years+ - NCT06493734Recruiting
SBRT after chemotherapy for inoperable bile duct cancer
This trial tests if a precise type of radiation (SBRT) can help people with inoperable bile duct cancer after they finish chemotherapy. It aims to control the tumor and improve outcomes.
Wilrijk, AntwerpAges 18 years+ - NCT06794086RecruitingPhase 3
SBRT and immunotherapy for colorectal cancer liver metastases
This trial combines targeted radiation (SBRT) with an immunotherapy drug (PD-1 inhibitor) to treat colorectal cancer that has spread to the liver and can't be removed by surgery. It aims to help shrink or control tumors in patients whose cancer has a normal DNA repair system (pMMR/MSS).
Guangzhou, GuangdongAges 18–75
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Common questions
- Are there clinical trials for stereotactic body radiation therapy (sbrt)?
- Yes. Clin2 currently lists 106 recruiting stereotactic body radiation therapy (sbrt) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stereotactic body radiation therapy (sbrt) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stereotactic body radiation therapy (sbrt) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.