Clinical trials · Philadelphia, PA
Stroke clinical trials in Philadelphia
We’re tracking 35 recruiting stroke studies with a site in or near Philadelphia — including Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT07592221Recruiting
Electrical Stimulation for Foot Drop After Stroke
This study tests a combination of two types of electrical stimulation to help improve foot drop (difficulty lifting your foot when walking) in people who've had a stroke. The goal is to help you walk more naturally and safely.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Philadelphia, PennsylvaniaAges 1–120 - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06368648Recruiting
Study of a new forehead sensor for brain pressure monitoring
This study tests a new sensor that measures brain pressure from outside the head. It is for people who are already in the hospital getting their brain pressure and blood pressure monitored continuously.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06968663RecruitingPhase 2
Brain stimulation with speech therapy for recent stroke aphasia
This study tests if adding a non-invasive brain stimulation technique (transcranial magnetic stimulation) to language therapy can improve speech recovery in people who had a stroke 2 to 6 weeks ago and now have aphasia (trouble speaking or understanding language).
Philadelphia, PennsylvaniaAges 18–85 - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Philadelphia, PennsylvaniaAges 18–90 - NCT06530693Recruiting
Improving emergency stroke care in the ambulance
This study looks at how emergency medical teams can better help people with stroke or mini-stroke symptoms. It aims to improve the way stroke care is started in the ambulance.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07143019Recruiting
A new device for treating wide-necked brain aneurysms
This trial tests a special device (p48/64 MW HPC) to treat certain brain aneurysms that are wide-necked or have a shape that makes them hard to treat. It might help people with aneurysms that haven't ruptured or that have been treated before and are now coming back.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05531461Recruiting
Imaging study after clot removal with Tigertriever device
This study looks at brain images and thinking (cognition) after treatment to remove a large artery blood clot using the Tigertriever. It may help doctors understand how well the procedure works and how it affects long-term brain function.
Philadelphia, PennsylvaniaAges 18–75 - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06632587Recruiting
Early vs. late skull replacement after brain surgery
This trial compares putting the skull piece back early (around 8 weeks after the initial surgery) versus later (after 8 weeks) in people who had a hemicraniectomy for high brain pressure. The goal is to see which timing leads to better outcomes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06842745RecruitingPhase 2
Brain stimulation plus language therapy for mild aphasia
This study tests whether combining brain stimulation (TMS) with language therapy can help people with mild aphasia after a stroke. It aims to improve speaking and understanding.
Philadelphia, PennsylvaniaAges 40–85 - NCT06092814Recruiting
Brain stimulation to boost language after stroke
This study tests whether a gentle electrical current (tACS) applied to the scalp can improve language abilities in people with aphasia after a stroke. Healthy volunteers are also needed as a comparison group.
Philadelphia, PennsylvaniaAges 18–85 - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Philadelphia, PennsylvaniaAges 18–80 - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07362303Recruiting
Neuralert stroke monitor study for high-risk patients
This trial tests a device that monitors for stroke in adults who are at high risk after certain heart or blood vessel procedures. It could help detect a stroke early so you get treated faster.
Philadelphia, PennsylvaniaAges 22 years+ - NCT06904911RecruitingPhase 2
Study of tenecteplase into the artery after clot removal for stroke
This study tests a clot-dissolving drug called tenecteplase given directly into the artery after a mechanical thrombectomy (clot removal). The goal is to see if it helps improve blood flow to the small vessels in the brain after the main clot is removed.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04897334Recruiting
Brain stimulation plus rehab to improve thinking after stroke
This study tests whether a noninvasive brain stimulation treatment, combined with rehabilitation, can improve thinking and other “neurocognition” problems after a recent stroke. It may help people whose thinking has been affected by stroke within the past month.
Philadelphia, PennsylvaniaAges 18–90 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05140148RecruitingPhase 2
Amantadine to help recovery after stroke
This Phase 2 study tests whether the medicine amantadine can improve recovery after a recent stroke. It may help some people regain function during early rehabilitation.
Philadelphia, PennsylvaniaAges 18–85 - NCT06368193Recruiting
Neuralert Stroke Monitor Pilot Study
This pilot study tests a new stroke-detection device for patients at high risk of stroke while in the hospital, especially after heart or blood vessel surgery. The device monitors for signs of stroke so doctors can respond quickly.
Philadelphia, PennsylvaniaAges 22 years+
Hear when a new Stroke trial opens near Philadelphia, PA
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Stroke trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting stroke studies listed above.
- Hospital of the University of Pennsylvania · 6 studies
- University of Pennsylvania · 5 studies
- Temple University Hospital · 3 studies
- The Hospital of the University of Pennsylvania · 3 studies
- 3401 N Broad street
- Capital Health Regional Medical Center
- Christiana Care
- Christiana Care Health Services, Inc.
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting stroke studies in Pennsylvania.
Common questions
- Are there stroke clinical trials near Philadelphia?
- Yes. We're currently tracking 35 recruiting stroke studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.