Clinical trials · Chicago, IL
Stroke clinical trials in Chicago
We’re tracking 53 recruiting stroke studies with a site in or near Chicago — including Early Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Chicago, IllinoisAges 18–80 - NCT06666673RecruitingEarly Phase 1
Effects of a muscle relaxant on arm movement after stroke
This study looks at how the brain controls arm movements after a stroke. It tests whether a medication called tizanidine, which relaxes muscles, can improve arm function when combined with physical therapy.
Chicago, IllinoisAges 18–80 - NCT05849532Recruiting
Home electrical exercise for walking after stroke
This trial tests a home-based program using electrical stimulation to help people with long-term stroke improve walking and leg movement. If you qualify, you may use the device and a smartphone app at home with guidance from the study team.
Chicago, IllinoisAges 18–90 - NCT07115940Recruiting
Clot removal after 24 hours for stroke patients
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
Chicago, IllinoisAges 18–85 - NCT04477330Recruiting
Brain stimulation to improve walking after a stroke
This study tests whether a brain stimulation method (“cortical priming”) can improve walking after a stroke. It may help people with ongoing walking problems improve gait and leg control over a rehabilitation program.
Chicago, IllinoisAges 18 years+ - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Chicago, IllinoisAges 18–79 - NCT06655636Recruiting
Testing a new robotic brace to help stroke survivors open their hand
This trial tests a wearable robotic device (ExoNET) that helps stroke survivors with hand weakness. It aims to see if the device is safe and helpful for people who had a stroke at least 8 months ago and still have trouble using their arm and hand.
Chicago, IllinoisAges 40–70 - NCT05907629Recruiting
MRI study comparing blood thinners after a certain stroke
This trial looks at MRI scans to compare two types of blood-thinning medicines (one that affects blood-clotting and one that affects platelets) after a recent stroke caused by severe narrowing in certain brain arteries. It may help doctors understand which treatment works best while checking how the blood vessels and brain tissue look on MRI.
Chicago, IllinoisAges 18 years+ - NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Chicago, IllinoisAges 18 years+ - NCT04957355Recruiting
NMES therapy to improve balance and reduce falls after stroke
This trial tests whether NMES (a small electrical stimulation you feel on the skin) can improve balance and lower fall risk in people with stroke-related weakness. It may help you walk more steadily and safely, while the study measures balance and fall-related outcomes.
Chicago, IllinoisAges 18–90 - NCT06094478Recruiting
Stroke emergency protocol study
This study tests a hospital stroke protocol to quickly evaluate and manage patients with a stroke caused by a clot (AIS), bleeding in the brain (ICH), or bleeding around the brain (SAH). It may help improve emergency care and outcomes.
Chicago, IllinoisAges 18 years+ - NCT03264261Recruiting
Therapy to improve walking after stroke by using affected arm
This study tests a walking-focused therapy called constraint induced movement therapy (CI therapy) to improve walking after a stroke. It may help people walk faster and more safely by encouraging more use of the more affected side.
Chicago, IllinoisAges 21–75 - NCT05756257Recruiting
MRI study of blood pressure swings after ischemic stroke
This trial looks at whether changes in blood pressure after an ischemic stroke (a stroke caused by blocked blood flow) are linked to recovery and outcomes. You may be asked to have MRI scans soon after arriving to help researchers understand who is at higher risk and why.
Chicago, IllinoisAges 18 years+ - NCT03300141Enrolling by invitation
Robotic arm training with visual feedback after stroke
This trial tests a robotics-based training program that helps people practice reaching with both the arm and hand, using real-time visual guidance. It may help improve how smoothly and accurately you can reach after stroke.
Chicago, IllinoisAges 18 years+ - NCT06029491Recruiting
Studying a new suction device for stroke treatment
This trial tests a new device that removes blood clots in the brain using suction. It is for people having a large-vessel ischemic stroke who can be treated within 8 hours of symptoms starting.
Chicago, IllinoisAges 18–80 - NCT03869138Recruiting
Improving physical function after stroke using alternative therapies
This study tests alternative therapies to help improve physical abilities like walking, balance, and arm/leg function after a stroke. It may help if you can follow instructions and safely participate in supervised movement exercises.
Chicago, IllinoisAges 18–90 - NCT06870812Recruiting
Quick removal of brain bleed clot study
This trial tests a rapid procedure to remove a blood clot in the brain after a specific type of stroke. It might help people with a moderate-sized bleed in the front part of the brain if treatment can start within 24 hours.
Chicago, IllinoisAges 18–70 - NCT06656754RecruitingEarly Phase 1
IsoReach: A study on reaching after stroke
This trial tests a new way to measure how people reach for objects, looking at differences between healthy adults and those who have had a stroke. The goal is to understand how stroke affects movement so better therapies can be developed.
Chicago, IllinoisAges 18 years+ - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Chicago, IllinoisAges 18 years+ - NCT06400186Recruiting
Walking training to improve balance after stroke
This trial tests a new walking training method designed to help you improve your balance after a stroke. It's for people who have had a stroke more than 6 months ago and can walk a short distance, with or without a cane or simple ankle brace.
Chicago, IllinoisAges 18–80 - NCT03401762Recruiting
Wearable device training for stroke arm coordination
This trial tests a wearable device and training task to help improve how stroke-affected arm muscles work together. It may help reduce unwanted “extra muscle effort” and improve control in people with recent or long-term stroke.
Chicago, IllinoisAges 21 years+ - NCT07806097Recruiting
Self-directed arm gaming during stroke rehab
This trial tests whether playing arm-focused video games on your own helps improve arm movement while you're in the hospital for stroke rehabilitation. You would play games that involve moving your arm and hand, and the goal is to see if this makes your recovery better.
Chicago, IllinoisAges 18 years+ - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Chicago, IllinoisAges 18 years+ - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
Chicago, IllinoisAges 18–70
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Stroke trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting stroke studies listed above.
- Northwestern University · 5 studies
- University of Chicago Medical Center · 5 studies
- Rush University Medical Center · 4 studies
- Shirley Ryan AbilityLab · 4 studies
- University of Chicago · 3 studies
- University of Illinois at Chicago · 3 studies
- Advocate Aurora Research Institute · 2 studies
- Central DuPage Hospital · 2 studies
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting stroke studies in Illinois.
Common questions
- Are there stroke clinical trials near Chicago?
- Yes. We're currently tracking 53 recruiting stroke studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.