Clinical trials · Raleigh–Durham, NC
Stroke clinical trials in Raleigh–Durham
We’re tracking 19 recruiting stroke studies with a site in or near Raleigh–Durham — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Raleigh–Durham
- NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Raleigh, North CarolinaAges 18 years+ - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Raleigh, North CarolinaAges 1–120 - NCT06368648Recruiting
Study of a new forehead sensor for brain pressure monitoring
This study tests a new sensor that measures brain pressure from outside the head. It is for people who are already in the hospital getting their brain pressure and blood pressure monitored continuously.
Raleigh, North CarolinaAges 18 years+ - NCT06226805RecruitingPhase 2
Testing BB-031 for recent ischemic stroke
This study tests an experimental drug called BB-031 to see if it can safely help people who have had a recent ischemic stroke (a clot that blocks blood flow to the brain). The trial is for people who can get to the hospital within 24 hours of their first symptoms and have a moderate to severe stroke.
Raleigh, North CarolinaAges 18 years+ - NCT06027788Recruiting
Embolic protection during heart valve surgery
This trial tests a device that may help protect your brain from small particles during heart valve surgery. It is for people 60 and older having certain types of valve replacement or repair.
Durham, North CarolinaAges 60 years+ - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Durham, North CarolinaAges 18 years+ - NCT06440707RecruitingPhase 2
Brain stimulation for recent stroke recovery
This trial tests a safe, non-invasive brain stimulation technique called tDCS to help people recover from a recent stroke. It's for people who cannot have the standard clot-removal procedure and who can start treatment within 24 hours of their stroke.
Durham, North CarolinaAges 18 years+ - NCT06759558RecruitingPhase 2
Zuranolone for post-stroke depression
This trial tests a new medicine called zuranolone (allopregnanolone) for people with depression after a stroke. It aims to see if the drug can help improve mood when taken over a short period.
Durham, North CarolinaAges 21–65 - NCT07220005Recruiting
Ultrasound brain stimulation for arm weakness after stroke
This study tests a new non-invasive therapy using low-intensity focused ultrasound to stimulate the brain area affected by a stroke, which may help improve arm weakness in people who have had a stroke more than 6 months ago.
Durham, North CarolinaAges 21 years+ - NCT06765642Recruiting
Brain stimulation for hand strength after stroke
This study tests whether a safe, non-invasive brain stimulation technique (called rTMS) can improve hand strength and movement in people who have had a stroke at least 3 months ago. The treatment is delivered through a coil placed on the scalp and does not require surgery.
Durham, North CarolinaAges 21 years+ - NCT07098286Enrolling by invitation
Home rehab after stroke
This study tests a high-intensity home-based rehabilitation program for people who have had a stroke. It aims to help you recover strength and function in the comfort of your own home.
Durham, North CarolinaAges 18 years+ - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Durham, North CarolinaAges 18 years+ - NCT00682695Recruiting
Study genetic and environmental risks for brain bleeding stroke
This study looks at how genes and life factors may contribute to a type of stroke caused by bleeding in the brain. You may be eligible if you’ve had a spontaneous (not caused by injury or infection) brain bleed and can complete consent, interviews, blood pressure checks, and a DNA sample.
Durham, North CarolinaAges 18 years+ - NCT05907629Recruiting
MRI study comparing blood thinners after a certain stroke
This trial looks at MRI scans to compare two types of blood-thinning medicines (one that affects blood-clotting and one that affects platelets) after a recent stroke caused by severe narrowing in certain brain arteries. It may help doctors understand which treatment works best while checking how the blood vessels and brain tissue look on MRI.
Durham, North CarolinaAges 18 years+ - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Durham, North CarolinaAges 18 years+ - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Durham, North CarolinaAges 18–80 - NCT07050355Recruiting
Brain stimulation and exercise for depression after stroke
This study tests whether combining brain stimulation with aerobic exercise can help treat depression and improve walking in people who have had a stroke at least a year ago. If you have ongoing depressive symptoms and some leg weakness from your stroke, this treatment may help you feel better and walk more easily.
Durham, North CarolinaAges 21 years+ - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Durham, North CarolinaAges 18 years+ - NCT07121582Recruiting
Brain rhythm training for arm recovery after stroke
This trial tests a way to retrain your brain's rhythms after a stroke to help you move your arm and hand better. It uses a non-invasive head coil (TMS) to stimulate the brain while you squeeze a grip device.
Chapel Hill, North CarolinaAges 45–80
Hear when a new Stroke trial opens near Raleigh–Durham, NC
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Stroke trials in other cities
Where these studies are running near Raleigh–Durham
Institutions with a site for the recruiting stroke studies listed above.
- Duke University Medical Center · 10 studies
- Duke University · 4 studies
- WakeMed Health & Hospitals · 3 studies
- UNC Children's Hospital · 2 studies
- Bondurant Hall
- Duke Medical Center Hospital
- University of North Carolina
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting stroke studies in North Carolina.
Common questions
- Are there stroke clinical trials near Raleigh–Durham?
- Yes. We're currently tracking 19 recruiting stroke studies with a site near Raleigh–Durham, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study near Raleigh–Durham?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Raleigh–Durham to take part?
- Not necessarily. These studies have a site near Raleigh–Durham, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open near Raleigh–Durham regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.