Clinical trials
Therapy clinical trials
Below are recruiting therapy clinical trials, each written for real people, not researchers. We’re tracking 7,177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04318678RecruitingPhase 1
CD123 CAR T-cell therapy for relapsed leukemia and related cancers
This early-phase study tests a lab-made immune therapy (CD123 CAR T cells) for children and young adults up to age 21 whose cancer has come back or didn’t respond to treatment. The goal is to see if these CAR T cells can find and attack cancer cells that carry a marker called CD123.
Memphis, TennesseeAges Up to 21 years - NCT04335487Recruiting
Online therapy program for PTSD symptoms in public safety workers
This study tests an internet-based cognitive-behavioral therapy (an online talk-therapy style program that helps you manage thoughts and feelings) to reduce PTSD symptoms in public safety personnel. You may be able to join if you have PTSD-like symptoms and can safely take part in online treatment.
Regina, SaskatchewanAges 18 years+ - NCT04172532RecruitingPhase 1/Phase 2
New targeted drug with radiation for locally advanced pancreatic cancer
This Phase 1/2 trial tests adding peposertib, a targeted anti-cancer drug, to standard radiation for people with locally advanced pancreatic adenocarcinoma. It aims to improve control of the cancer after initial chemotherapy and determine whether the combo is safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT04188535Recruiting
Scanning tumor response during radiation therapy
This study uses repeated MRI scans during radiation treatment to see how tumors change. It may help doctors adjust treatment and improve outcomes for many types of cancer.
Boston, MassachusettsAges 18 years+ - NCT04187703RecruitingEarly Phase 1
Testing azacitidine and decitabine for bone marrow cancers
This early-phase study tests whether combining two “epigenetic” medicines—azacitidine and decitabine—can improve outcomes for certain bone marrow cancers. It may help if you have a type of myelodysplastic syndrome (MDS) or MDS/MPN overlap that is expected to be sensitive to these medicines.
Cleveland, OhioAges 18 years+ - NCT04178174RecruitingPhase 3
Boost radiation for HPV throat cancer with shorter treatment
This trial studies whether adding a precise “extra boost” to radiation can work as well as (or better than) standard radiation for HPV-related oropharynx cancer, while keeping the overall treatment shorter. It may help improve tumor control while aiming for manageable side effects.
London, OntarioAges 18 years+ - NCT04171830Enrolling by invitation
Screening for palliative needs in the last year of life
This trial uses a special tool to check if patients in the hospital have unmet needs for comfort and quality-of-life care. It is designed for patients who may be in their final year of life, helping doctors and nurses offer extra support sooner.
Brampton, OntarioAges Any age - NCT04201704Recruiting
Less IV fluids for children after trauma
This trial studies whether giving children less fluid through a vein after serious injury helps them recover safely. Children are enrolled soon after arrival to the ICU so the team can compare outcomes between different fluid amounts.
Buffalo, New YorkAges 6 months–15 years - NCT04151082RecruitingPhase 1/Phase 2
Steroid therapy for late nerve damage after throat cancer radiation
This trial tests whether high-dose steroids (prednisone or methylprednisolone) can improve symptoms of nerve damage that may occur years after radiation treatment for oropharyngeal cancer. It includes a registry for tracking similar nerve issues in head and neck cancer survivors.
Houston, TexasAges 18 years+ - NCT04165772RecruitingPhase 2
Dostarlimab for locally advanced mismatch-repair deficient solid tumors
This Phase 2 trial studies dostarlimab (an immune therapy that targets PD-1) given before surgery or other initial treatment. It aims to shrink certain locally advanced cancers that have mismatch repair deficiency, potentially making treatment easier and improving outcomes.
Hartford, ConnecticutAges 18 years+ - NCT04157127RecruitingPhase 1
Pancreatic cancer vaccine with chemotherapy before/around surgery
This early-stage trial tests a personalized immune “vaccine” made from dendritic cells, given alongside standard chemotherapy for pancreatic cancer that may be removable by surgery (resectable or borderline resectable). If it works, it may help your immune system better recognize and attack the cancer around the time of treatment.
Houston, TexasAges 18 years+ - NCT04220190RecruitingPhase 2/Phase 3
Study drug made from your immune cells for ALS
This trial tests RAPA-501, a treatment made using your own immune cells, to slow progression of ALS. It may help by changing how your immune system responds in ALS.
Boston, MassachusettsAges 18 years+ - NCT04202341Recruiting
Registry for people with generalized myasthenia gravis on Alexion treatment
This study is a registry, meaning it collects health and disease information from people with generalized myasthenia gravis (gMG) who are receiving Alexion C5 “inhibition” therapies. Your data can help researchers better understand real-world outcomes and disease patterns over time.
Birmingham, AlabamaAges 18 years+ - NCT04097145Recruiting
Heart valve repair for severe leaking tricuspid valve
This trial tests a catheter-based procedure (done through the blood vessels) to repair a severely leaky tricuspid valve. It may help people with symptoms or past hospitalizations from tricuspid valve leakage who are higher-risk for standard surgery.
Phoenix, ArizonaAges 18 years+ - NCT04068155Recruiting
Radiation device for certain skin cancers you can treat locally
This trial tests a radiation-emitting device placed near the tumor to treat certain malignant skin cancers that can be fully covered. It may help shrink or control the cancer at the skin site where the device is applied.
GrenobleAges 18 years+ - NCT04104412RecruitingPhase 1
Stem cell injection study for long-lasting disc back pain
This Phase 1 study tests the safety and early effectiveness of an umbilical cord stem cell injection for people with persistent lumbar (lower back) disc-related pain that has not improved with standard care. If you qualify, it may offer a new treatment option, while researchers closely monitor side effects and pain changes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04085848Recruiting
Music program for suicidal thoughts and emotional pain
This trial tests whether listening to music can help reduce psychological pain and suicidal mood during a short stay in a psychiatric hospital. You would be asked to stay in the hospital for about 48 to 60 hours and complete study steps after giving consent.
Saint-PaulAges 18 years+ - NCT04068012Recruiting
Test of a decision support tool for children with PARDS
This trial tests a computer “decision support” tool to help the care team manage treatment for children with PARDS who are just starting a breathing machine. It may help clinicians choose care steps and potentially support safer, more effective breathing management during the first days of ventilation.
Chicago, IllinoisAges 1 month–18 years - NCT04115267Recruiting
Registry study tracking side effects from radiation and medicines
This study follows people with cancer to better understand which treatments cause certain side effects when radiation is combined with targeted (molecular) medicines. Your participation may help doctors predict and manage side effects more safely in the future.
Montreal, QuebecAges 18 years+ - NCT04055220Recruiting
Regorafenib to keep bone cancer from coming back
This trial studies whether regorafenib given after first treatment helps patients with bone sarcoma stay in remission longer. It focuses on safety and whether the medicine can prevent the cancer from growing or returning.
BesançonAges 12 years+ - NCT04059172RecruitingEarly Phase 1
Ibuprofen plus acetaminophen for braces pain
This early study compares braces pain relief using: ibuprofen alone, ibuprofen plus acetaminophen together, or placebo (no active pain medicine). It may help find which approach works best and is safest for people starting orthodontic treatment.
Aurora, ColoradoAges 12–80 - NCT04127032Recruiting
Online therapy program for public safety workers’ stress and mood
This trial tests an internet-delivered cognitive behavioral therapy (an online talk-and-skills program) to help public safety personnel with symptoms of anxiety, depression, or post-traumatic stress. If you’re eligible, you may receive structured online support aimed at reducing distress and improving coping.
Regina, SaskatchewanAges 18 years+ - NCT04084730RecruitingPhase 2
3-day radiation after breast-conserving surgery for certain breast cancers
This trial tests whether a shorter, 3-day course of partial breast radiation after surgery works as well as standard radiation for women with early-stage breast cancer. It may help reduce time in treatment while aiming to keep cancer from coming back in the treated breast area.
Norwalk, ConnecticutAges 45 years+
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Common questions
- Are there clinical trials for therapy?
- Yes. Clin2 currently lists 7,177 recruiting therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.