Clinical trials
Traumatic Brain Injury clinical trials
Below are recruiting traumatic brain injury clinical trials, each written for real people, not researchers. We’re tracking 362 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06734026Recruiting
Enriched environment rehab for chronic brain injury
This study tests a rich, supportive environment (including exercise, social activities, and cognitive tasks) to help people with chronic brain injury improve their mobility and overall function. If you have a brain injury that happened more than 3 months ago and can stand with support, you may be able to join a program that focuses on your recovery.
Cleveland, OhioAges 18 years+ - NCT06584591Recruiting
Balance training study for people with traumatic brain injury
This study tests a new balance training program called NEUROBALANCE to help improve postural control in people who have had a traumatic brain injury. It uses a non-invasive brain stimulation technique (TMS) to see if it can help improve balance and walking.
West Orange, New JerseyAges 18–75 - NCT06595914Enrolling by invitation
Improving education for mild traumatic brain injury
This trial is working to improve how doctors and nurses teach patients about mild traumatic brain injury (mTBI) in the emergency room and after they go home. It may help you get clearer information and support during recovery.
Milwaukee, WisconsinAges 18 years+ - NCT06581003RecruitingPhase 3
Hyperbaric oxygen for veterans with lasting brain injury symptoms
This trial tests whether breathing pure oxygen inside a pressurized chamber (hyperbaric oxygen therapy) can help reduce long-term symptoms after a mild or moderate traumatic brain injury. It is for veterans and service members who have had a TBI at least one year ago and are still struggling with symptoms.
Tampa, FloridaAges 18–75 - NCT06551987Recruiting
Insomnia treatment for military members with mild brain injury
This study tests a behavioral insomnia therapy for active-duty service members who have had a mild traumatic brain injury and continue to have sleep problems and other symptoms. It aims to help improve sleep and recovery.
Fort Cavazos, TexasAges 18–45 - NCT06544408Recruiting
Brain stimulation for fast relief of PTSD
This study tests a rapid, non-invasive brain stimulation treatment to reduce PTSD symptoms. It aims to offer a faster way to help adults with PTSD feel better.
Tallahassee, FloridaAges 18–65 - NCT05716048RecruitingPhase 1
Rehab program study for adults with lasting brain injury symptoms
This Phase 1 trial tests a combined rehabilitation program to improve function in people living with moderate-to-severe traumatic brain injury (TBI) for at least a year. It may help people who still have new problems with learning and memory and who are not very physically active.
West Orange, New JerseyAges 18–65 - NCT06504238Recruiting
Non-invasive monitoring for acute brain injury
This trial tests special cameras and sensors that check your brain without surgery. It may help doctors watch for brain swelling and other problems more safely.
Boston, MassachusettsAges 18 years+ - NCT06477796Recruiting
Improving sleep in veterans with TBI and sleep problems
This study tests a new way to help Veterans with both a traumatic brain injury (TBI) and sleep problems get better rest. If you are a Veteran with sleep trouble and a history of TBI, this program may help improve your sleep without needing extra medication.
Portland, OregonAges 18–89 - NCT06480838Recruiting
Brain blood flow and thinking after traumatic brain injury
This study looks at how the brain controls its own blood flow after a moderate to severe traumatic brain injury (TBI). It uses MRI scans and thinking tests to understand recovery and help improve care for people like you.
Dallas, TexasAges 18–80 - NCT06467708Recruiting
Ear Stimulation for ICU Patients with Traumatic Brain Injury
This study tests a very small electrical device placed on the ear to see if it can help people with traumatic brain injury recover in the intensive care unit (ICU). The device sends gentle pulses to a nerve that may calm inflammation and improve brain function.
Dallas, TexasAges 18 years+ - NCT03321370Recruiting
Study of brain swelling after severe head injury surgery
This trial looks at changes in brain activity after severe traumatic brain injury (TBI) when patients need emergency skull surgery. The goal is to better understand what happens in the brain after surgery and whether earlier recognition could help care after injury.
Minneapolis, MinnesotaAges 18 years+ - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06370520Recruiting
Teen emotions screening after mild brain injury
This study screens teens aged 11 to 17 for emotional and mental health problems after a mild traumatic brain injury (mTBI, also called concussion or minor head injury). The goal is to find out if the hospital screening helps identify teens who may need extra support.
Sacramento, CaliforniaAges 11–17 - NCT06293300RecruitingPhase 2
Botulinum toxin for light sensitivity after brain injury
This study tests if botulinum toxin type A (Botox) can reduce long-term light sensitivity in people who have had a traumatic brain injury at least a year ago. You must have had light sensitivity for 6 months or more and not have had Botox for face or mouth conditions before.
Miami, FloridaAges 18 years+ - NCT06282965RecruitingPhase 1/Phase 2
Angiotensin (1-7) for moderate to severe brain injury
This study tests a drug called Angiotensin (1-7) to see if it helps people recover from moderate to severe traumatic brain injury. It may reduce damage and improve healing when given shortly after the injury.
Tucson, ArizonaAges 18 years+ - NCT06192342Recruiting
Breathing machine settings for brain injury patients
This study looks at how different breathing machine settings affect people with new brain or spinal cord injuries who need help breathing. It only includes people with healthy lungs to see which ventilator settings work best.
Ciudad Autonoma de Buenos Aires, Buenos AiresAges 16 years+ - NCT06188364RecruitingEarly Phase 1
Helping caregivers of traumatic brain injury patients
This trial tests if mobile health support (texts and calls) helps caregivers of people with traumatic brain injury after rehab. You may join as the main caregiver if you supervise daily care and have a smartphone or can get one.
Richmond, VirginiaAges 18 years+ - NCT06112093RecruitingPhase 1
Magnetic brain stimulation for headaches after a concussion
This study tests whether a non-invasive magnetic pulse treatment (repetitive transcranial magnetic stimulation) can help people with long-lasting headaches following a mild concussion. If you are 18 to 55 years old and have had daily headaches for at least 3 months after your head injury, this study may help find a new way to relieve your pain.
Syracuse, New YorkAges 18–55 - NCT06109909Recruiting
Brain training for light sensitivity after mild head injury
This study tests if a type of brain training called neurofeedback can help reduce sensitivity to light in people who have had a mild traumatic brain injury, also known as a concussion, at least 6 months ago.
Boston, MassachusettsAges 18–65 - NCT06105892Recruiting
Eye recovery program for mild brain injury symptoms
This study tests a home-based eye exercise program for people with mild traumatic brain injury who have ongoing vision problems like blurring or trouble focusing. It aims to help your eyes work together better and reduce symptoms.
Albuquerque, New MexicoAges 18–40 - NCT06115291Enrolling by invitation
Smell training study for adults with smell loss
This study tests whether a daily smell training routine can help improve your sense of smell. It is open to adults with any kind of smell loss or problem, including those with conditions like COVID-19 or head injury, but not certain brain diseases.
Kansas City, KansasAges 18–80 - NCT06062888RecruitingPhase 2/Phase 3
Testing fresh frozen plasma for traumatic brain injury
This trial tests whether giving fresh frozen plasma (a blood product) soon after a traumatic brain injury can help people recover better. It is for adults aged 18 to 65 with moderate to severe TBI confirmed by CT scan.
Chicago, IllinoisAges 18–65 - NCT06073886RecruitingPhase 2
Better brain stimulation for long-lasting concussion symptoms
This trial tests whether personalized brain stimulation can help people who have ongoing symptoms more than 20 on a standard concussion scale, such as headaches, dizziness, or trouble concentrating, after a mild head injury in the past year.
Westwood, Los Angeles, CaliforniaAges 18–65
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Common questions
- Are there clinical trials for traumatic brain injury?
- Yes. Clin2 currently lists 362 recruiting traumatic brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a traumatic brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a traumatic brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.