Clinical trials
Traumatic Brain Injury clinical trials
Below are recruiting traumatic brain injury clinical trials, each written for real people, not researchers. We’re tracking 362 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06073886RecruitingPhase 2
Better brain stimulation for long-lasting concussion symptoms
This trial tests whether personalized brain stimulation can help people who have ongoing symptoms more than 20 on a standard concussion scale, such as headaches, dizziness, or trouble concentrating, after a mild head injury in the past year.
Westwood, Los Angeles, CaliforniaAges 18–65 - NCT03578003Recruiting
Bright morning light to improve sleep in veterans
This study tests whether using bright morning light can improve sleep quality in veterans. You may be able to join if you’re not already using a light box and you don’t have certain eye or mood conditions.
Portand, OregonAges 18 years+ - NCT06024122Recruiting
Brain development after mild concussion in young children
This study looks at how a mild concussion affects brain development in young children (ages 3–5) compared to kids with other minor injuries like a broken arm. It involves one MRI scan and some simple check-ups to see how the brain heals over time.
RennesAges 3 years–5.9 years - NCT05942638Enrolling by invitation
Tracking how concussion affects college driving over time
This study follows young adults who drive to see how a concussion may affect driving abilities over time. You may be asked to complete driving- and health-related assessments, and the results could help improve safety and guidance after concussion.
Athens, GeorgiaAges 18 years+ - NCT05951777RecruitingPhase 2
Stem cells from your own fat for chronic brain injury
This trial tests whether stem cells taken from your own fat and given through an IV can help people with long-term brain damage from a head injury. It is for adults who have not gotten better with standard treatments.
Houston, TexasAges 18–55 - NCT05929833Enrolling by invitation
Brain injury education program for recovery at home
This study tests a recovery-focused brain injury education and support program for people with traumatic brain injury (TBI) who plan to go home after hospital stay. If you qualify, you and a caregiver/friend may get training and therapy support aimed at improving recovery.
Durham, North CarolinaAges 18 years+ - NCT05848297Recruiting
Robotic ultrasound monitoring for severe traumatic brain injury
This trial tests whether a robotic system using a bedside ultrasound test (TCD) can safely monitor brain blood flow in adults with severe traumatic brain injury soon after the injury. It may help the care team track changes earlier and adjust treatment sooner.
Davis, CaliforniaAges 18 years+ - NCT05825027Recruiting
Sorting out risk in children with a recent concussion
This study looks at how to identify which children are at higher risk after a concussion and how they should be monitored. It may help doctors choose safer, more personalized follow-up care after a recent head injury.
Durham, North CarolinaAges 11–17 - NCT05826912Enrolling by invitationPhase 2
Testing new treatment for acute brain injury after a fall or hit
This study tests an investigational treatment to improve outcomes after a recent non-penetrating traumatic brain injury (like a fall or car crash). It uses early CT/MRI imaging and a blood test soon after injury to see who benefits and how well the treatment works.
San Francisco, CaliforniaAges 18–65 - NCT05819008Recruiting
Online brain testing for people with neurological conditions
This trial studies how well a remote, online memory and thinking assessment works for people with neurological disorders or injuries. You may be invited if you can do the computer-based testing and speak Swedish.
UmeåAges 18 years+ - NCT05786729Enrolling by invitationPhase 1/Phase 2
Aerobic exercise program after traumatic brain injury
This trial tests whether a supervised aerobic exercise plan is safe and helpful for people recovering from traumatic brain injury (TBI). It may help improve physical fitness and functioning through regular walking and aerobic training.
Bakersfield, CaliforniaAges 18–60 - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05725993Recruiting
Study of tiny blood-vessel brain injury after head trauma
This study follows people with a moderate, non-penetrating traumatic brain injury (TBI) to see how small blood-vessel damage changes over time. It uses brain scans to learn what happens after a serious accident, which may help improve future care.
Philadelphia, PennsylvaniaAges 18–65 - NCT05682677Recruiting
Brain stimulation plus cognitive training for depression after mild head injury
This study tests whether a combination of brain stimulation and cognitive training can reduce depression symptoms in people who have ongoing mild traumatic brain injury (TBI). It may help by targeting both mood and thinking/processing skills affected after mTBI.
La Jolla, CaliforniaAges 18–65 - NCT05647044RecruitingPhase 1
Brain stimulation to reduce impulsivity and suicidal thoughts after mild TBI
This early-stage study tests whether a noninvasive brain stimulation treatment (called iTBS) can reduce impulsivity and suicidal thoughts in Veterans who have had a mild traumatic brain injury (mTBI) and recent suicidal thinking. If you qualify, you may be offered a monitored treatment plan and assessments for safety and symptom changes.
Hines, IllinoisAges 22–65 - NCT05663034Recruiting
Compare CBT-I vs MBTI for sleep and trauma symptoms after TBI
This study compares two types of talk-based therapy to help veterans with long-lasting insomnia after a traumatic brain injury (TBI), and also looks at related post-trauma stress symptoms. It may help you improve sleep and reduce how much these symptoms affect daily life.
Eglin Air Force Base, FloridaAges 18 years+ - NCT05616910Enrolling by invitationPhase 2
Inhaled nitric oxide for microvascular problems after brain injury
This Phase 2 study tests whether inhaled nitric oxide can improve tiny blood-flow problems in the brain after traumatic brain injury. If you qualify, you may receive inhaled nitric oxide and be monitored for safety and recovery.
Philadelphia, PennsylvaniaAges 18–75 - NCT05527041Enrolling by invitation
Portable eye test device for mild concussion after injury
This study tests a portable device that uses eye checks to assess people with a mild concussion after a head or body impact. It may help find concussion-related changes in settings like deployment or far-forward locations.
West Point, New YorkAges 17–35 - NCT05446584RecruitingPhase 2
Study memory changes in people with past mild head injury
This Phase 2 study looks at how memory problems (amnestic mild cognitive impairment) may relate to a history of a mild traumatic brain injury. It compares people with a past mild head injury to people without one to better understand what might be driving memory symptoms.
Dallas, TexasAges 55 years+ - NCT05364749Recruiting
CT scan approach for people on blood thinners after head injury
This trial looks at a more targeted CT scan plan for people who are on blood thinners and have a head injury. It may help doctors decide who needs imaging right away and how to keep care safe and efficient.
Vancouver, British ColumbiaAges 16 years+ - NCT05402761Recruiting
Nurse-guided sleep program for insomnia after brain injury
This trial studies whether nurse-guided behavioral sleep therapy can improve insomnia in people recovering after a traumatic brain injury (TBI). It may help you sleep better by targeting sleep habits and insomnia symptoms.
TaipeiAges 20–65 - NCT05393492Recruiting
Emotion and behavior skills after a brain injury
This study tests a structured program to help people after a brain injury manage emotions and challenging behaviors, and to reduce distress for them and their families. If you (or your family member) can participate safely and understand the activities in French, you may be invited to join a group and assessments.
Illkirch-GraffenstadenAges 18 years+ - NCT05327829RecruitingEarly Phase 1
Testing a brain-stimulation approach after concussion recovery
This early study tests whether a brain-stimulation method can help after recovery from a mild to moderate traumatic brain injury (TBI), sometimes called concussion. It also may include healthy volunteers to compare safety and computer-based brain measures.
Minneapolis, MinnesotaAges 18 years+ - NCT05261477Recruiting
Kid Brain Injury Education and Care Navigation Program
This trial tests a family support program that teaches caregivers and helps coordinate outpatient care after a traumatic brain injury. It may help families better understand recovery and connect with rehabilitation services.
Colorado Springs, ColoradoAges 3 years+
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Common questions
- Are there clinical trials for traumatic brain injury?
- Yes. Clin2 currently lists 362 recruiting traumatic brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a traumatic brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a traumatic brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.