Clinical trials
Type 2 diabetes clinical trials
A condition where the body can’t use insulin properly, raising blood sugar. We’re tracking 1,079 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04187443RecruitingPhase 1
Drug MS-553 for diabetic eye swelling with reduced vision
This Phase 1 trial tests MS-553 to see how it works and how safely it can be given to people with diabetic retinopathy causing central macular swelling (macular edema). You may be considered if your vision and eye scan results match, and if you can follow frequent study visits.
Changsha, HunanAges 18 years+ - NCT04257877Recruiting
Studying blood proteins in children with type 1 diabetes
This study looks at blood protein patterns in children with type 1 diabetes to better understand the condition. It may help researchers find markers linked to how diabetes is doing, especially in young, early-stage children.
ThessalonikiAges 5–10 - NCT04432025Recruiting
Medication after weight-loss surgery for type 2 diabetes
This trial looks at whether a specific diabetes medicine given after bariatric (weight-loss) surgery can improve blood sugar control in people with type 2 diabetes. You might be considered if you are eligible for this surgery and meet the weight criteria.
DublinAges 18 years+ - NCT04442451Recruiting
Study how fatigue happens in prediabetes and type 2 diabetes
This study looks at why people with prediabetes or type 2 diabetes may feel unusually tired during activities. You may be asked to do exercise testing and answer questions to help researchers understand the body changes behind fatigue.
Ann Arbor, MichiganAges 30–85 - NCT04455867Recruiting
Study of type 2 diabetes risk and early treatment
This study looks at people who may be on the way to developing type 2 diabetes or who have it, to see how to help and better understand the condition. Depending on the part of the study you join, it may include brain scans and sleep testing.
Toronto, OntarioAges 18 years+ - NCT04501406RecruitingPhase 2
Low-dose pioglitazone for fatty liver disease in people with type 2 diabetes
This Phase 2 study tests whether low-dose pioglitazone can improve NASH, a type of fatty liver disease, in adults who also have type 2 diabetes. You may be able to join if your diabetes medicines and lab tests meet specific safety and stability requirements.
Gainesville, FloridaAges 21–75 - NCT04579900Recruiting
Study how gut microbes affect type 2 diabetes risk
This study looks at how differences in gut microbes may relate to risk of developing type 2 diabetes. It may help researchers understand who is more likely to develop diabetes, and why.
Québec, QuebecAges 18–60 - NCT04583800Recruiting
Tracking heart failure risk and memory change in diabetes
This study follows adults with type 2 diabetes to see who may develop heart problems and who may have memory or thinking changes over time. It may help doctors better predict risk and plan earlier support.
LilleAges 18 years+ - NCT04621396Recruiting
Birth cohort study following families in Manitoba
This study follows pregnant people and their children over time in Manitoba. It aims to better understand diabetes during pregnancy and how it may affect children’s health.
Winnipeg, ManitobaAges Up to 18 years - NCT04670666RecruitingPhase 3
Study of Madalena for type 2 diabetes not controlled
This Phase 3 study tests Madalena to improve blood sugar control in adults with type 2 diabetes that hasn’t met targets despite diet, exercise, and diabetes medicines. You may join if your recent blood sugar tests and body size fall within specific ranges and you don’t have key medical exclusions.
Hortolândia, São PauloAges 18 years+ - NCT04783441Recruiting
Continuous glucose sensor study after kidney transplant
This study checks whether using a continuous glucose monitor (a sensor that tracks sugar throughout the day) is helpful and practical for people with a recent kidney transplant and type 2 diabetes on insulin. You may need to wear the sensor continuously and still do finger-stick glucose checks for safety.
Sacramento, CaliforniaAges 18 years+ - NCT04791371Recruiting
Study how fitness and insulin resistance relate to diabetes
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
Aurora, ColoradoAges 30–55 - NCT04831385Recruiting
CBT-I sleep therapy to improve blood sugar in older adults
This study tests whether a structured therapy for insomnia (CBT-I) can help improve blood sugar control in older adults with type 2 diabetes. It targets people who have both high blood sugar levels and troublesome insomnia, aiming to see if better sleep improves glycemic measurements.
Hong KongAges 60 years+ - NCT04874012RecruitingPhase 2
Taurine supplement study for blood sugar, fats, and inflammation
This Phase 2 study tests whether taking taurine affects blood sugar control, cholesterol/fats, and inflammation in people with type 2 diabetes. It may help by improving these lab markers, which are linked to long-term health risks.
Porto Alegre, Rio Grande do SulAges 30–80 - NCT04889053Recruiting
CT heart scan study in adults with type 2 diabetes
This trial uses a low-dose CT scan of the heart’s arteries to measure coronary artery calcification in people with type 2 diabetes. It aims to better understand heart calcium buildup and may help improve risk assessment for people with diabetes.
HengyangAges 18 years+ - NCT04917471Recruiting
Testing nitrate to improve red blood cell function in type 2 diabetes
This study looks at whether taking nitrate can improve how red blood cells work in people with type 2 diabetes. You may be asked to follow a specific plan and avoid certain foods or medicines that could affect the results.
StockholmAges 18 years+ - NCT04932928Recruiting
Using a glucose sensor to improve type 2 diabetes
This study checks whether patient-guided lifestyle changes, supported by a continuous glucose monitor (a sensor), can improve blood sugar control in adults with type 2 diabetes. It may help you and your care team see how food, activity, and habits affect your readings.
SeoulAges 19–80 - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT04941794Recruiting
Test heart-related blood markers in people with type 2 diabetes
This study looks at blood tests (called biomarkers) to see if they can help predict chronic heart failure risk. It focuses on adults with type 2 diabetes over age 50 who do not already have certain heart conditions.
HjørringAges 50 years+ - NCT04943926Recruiting
Diet changes to help put type 2 diabetes into remission
This study tests whether specific dietary strategies can help people with type 2 diabetes reach remission (better blood sugar without ongoing high medication needs). You may be a good candidate if your diabetes is relatively recent, your weight is above a certain threshold, and your heart and other health conditions are stable.
Bergen, VestlandAges 24–70 - NCT04993482Recruiting
Tracks daily movement habits in adults with type 2 diabetes
This study looks at your usual 24-hour movement pattern (like being active, sitting, and sleeping). It may help researchers better understand daily behavior patterns in people with type 2 diabetes.
GhentAges 18–100 - NCT05008276Recruiting
Study of puberty, diabetes, and kidney stress in teens
This trial studies how puberty and blood sugar changes affect the kidneys in people with type 1 diabetes. It may help researchers understand early kidney risk and identify who needs closer monitoring.
Aurora, ColoradoAges 8–14 - NCT05026723Recruiting
Food plan to improve health for HIV and type 2 diabetes
This study tests whether a personalized “food as medicine” approach can help people manage health related to HIV and type 2 diabetes or prediabetes risk. If you struggle with having enough healthy food, the program may focus on practical ways to improve diet and support healthier blood sugar.
Chapel Hill, North CarolinaAges 18 years+ - NCT05041491RecruitingEarly Phase 1
Breaking up sitting time to improve blood sugar
This study tests whether changing how often you sit (adding movement breaks) can improve blood sugar control in people at risk for type 2 diabetes. It compares two activity patterns and uses monitoring and brief hospital-style visits with controlled food.
Aurora, ColoradoAges 18–64
Hear when a new Type 2 diabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for type 2 diabetes?
- Yes. Clin2 currently lists 1,079 recruiting type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.