Clinical trials
Weight Loss clinical trials
Below are recruiting weight loss clinical trials, each written for real people, not researchers. We’re tracking 194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06275061Recruiting
Obesity and metabolic surgery database study
This trial is building a database of people with obesity who have had or are planning to have weight loss surgery (metabolic or bariatric surgery). It helps doctors learn more about long-term results and safety.
Guangzhou, GuangdongAges Any age - NCT06302803Recruiting
Modified intermittent eating for weight loss trial
This trial tests a modified intermittent eating plan to help people with obesity lose weight and keep it off. It compares different eating schedules to see which works best for long-term weight control.
Guangzhou, GuangdongAges 18–75 - NCT06309563Recruiting
Essential amino acid diet for severe obesity
This study tests whether replacing some foods with essential amino acids (protein building blocks) can improve metabolism in people with severe obesity. It aims to find a non-surgical way to boost weight loss.
Oggebbio, VerbaniaAges 45–65 - NCT06322030Recruiting
Weight loss and exercise for stroke survivors
This study tests whether a weight loss and exercise program can help veterans who had a stroke at least 6 months ago and have some leg weakness. It aims to improve mobility and overall health.
Charleston, South CarolinaAges 40–80 - NCT06323889Recruiting
Intermittent fasting study for adults with obesity
This study tests whether intermittent fasting (alternating periods of eating and fasting) can help with weight loss and health in adults with obesity. It aims to see if this approach is safe and effective.
Zurich, Canton of ZurichAges 18–50 - NCT07178704Recruiting
Genes and metabolism after weight loss surgery
This study looks at how your genes and metabolism affect changes in body composition after weight loss surgery. It aims to understand why some people lose more weight or gain muscle differently than others.
Galveston, TexasAges 18–65 - NCT06335771Recruiting
Study on fat metabolism in obesity and diabetes
This study looks at how fat is processed in the body for people with different health conditions, including obesity and type 2 diabetes. It aims to find new ways to improve treatment by understanding these differences.
Columbia, MissouriAges 18–70 - NCT06467578Recruiting
Resting metabolic rate monitoring study
This study tests if you can measure your resting metabolic rate at home using a portable device. It will help researchers understand if this is easy and acceptable for people to do on their own.
Kelowna, British ColumbiaAges 19–65 - NCT06477900Recruiting
Text message reminders for weight loss in prediabetes
This trial tests whether getting regular text message reminders can help people with prediabetes lose more weight during a health program. It is for adults in Réunion who are already part of a local prediabetes support program.
Saint-Louis, RéunionAges 18 years+ - NCT06989437RecruitingPhase 2/Phase 3
Study of Ponsegromab for Pancreatic Cancer with Weight Loss
This study tests an experimental drug called ponsegromab for people with advanced pancreatic cancer who experience severe weight loss and fatigue. It aims to see if the drug can help improve weight and energy levels while you continue standard chemotherapy.
Birmingham, AlabamaAges 18 years+ - NCT06508840Recruiting
Clear Conversations: Better communication for weight and lung health
This study looks at how different communication styles affect people taking part in weight management or pulmonary rehab programmes in Derbyshire. It also involves health staff who attend a training session called Verbal Health Literacy.
Matlock, ChesterfieldAges 18–90 - NCT06517212RecruitingPhase 2
Tirzepatide for weight loss in MRD-positive early breast cancer
This study tests whether the weight-loss drug tirzepatide (Mounjaro) can help prevent breast cancer from coming back in people who are overweight and have a sign of leftover cancer cells in their blood (called MRD-positive). You must have already finished at least one year of hormone therapy for early-stage breast cancer.
Dallas, TexasAges 18 years+ - NCT06622382Recruiting
Weight loss study using a new procedure called BEAM
This study tests a procedure called BEAM to help people with obesity lose weight. It is for people who have tried other weight loss methods like diet, exercise, and medication but haven't succeeded.
ShatinAges 18–70 - NCT06636773Recruiting
Aerobic vs Aerobic Plus Yoga for Weight Loss
This study compares two exercise programs — aerobic exercise alone versus aerobic exercise combined with yoga — to see which helps adults with overweight or obesity lose weight. You would need to follow a diet plan and attend regular exercise sessions at the University of Kansas Medical Center.
Kansas City, KansasAges 18 years+ - NCT06653530Recruiting
Thread embedding acupuncture for weight loss
This trial tests a type of acupuncture called thread embedding to help with weight loss. It's for people who haven't had success with diet and exercise alone and have a higher body weight or weight-related health issues.
Beijing, Beijing MunicipalityAges 18–75 - NCT06702085Recruiting
Lifestyle changes for older adults with tinnitus and metabolic syndrome
This study tests whether lifestyle changes (like diet and exercise) can help older adults who have both metabolic syndrome and chronic tinnitus (ringing in the ears). It is for people 65 and older with class 1 obesity and long-term ear ringing in both ears.
Dokki, Giza GovernorateAges 65–75 - NCT06706284RecruitingPhase 4
GLP-1 agonist for diabetes after spinal cord injury
This trial tests whether a GLP-1 agonist (a type of diabetes medicine that also helps with weight loss) is safe and effective for people with spinal cord injury and type 2 diabetes who are not on other glucose-lowering drugs.
San Antonio, TexasAges 18–70 - NCT06720246Recruiting
Weight loss surgery and liraglutide study on thinking and long-term weight
This trial tests whether bariatric surgery or the drug liraglutide helps people with obesity lose weight and keep it off by looking at how it affects your thinking and behavior. It might help you understand which treatment works best for long-term success.
Milan, MilanAges 20–60 - NCT06734273RecruitingEarly Phase 1
Sleeve gastrectomy with tirzepatide for weight loss
This trial compares getting a sleeve gastrectomy alone versus getting it along with tirzepatide (a medicine that helps with weight loss and diabetes) to see if combining them leads to more weight loss. It may help people who are having their first sleeve gastrectomy.
Chicago, IllinoisAges 18–65 - NCT06736028Recruiting
Ketogenic diet for weight loss maintenance in obesity
This study tests whether a ketogenic diet helps people with obesity keep weight off by changing how your body burns energy and controls appetite. You will follow a low-carb, high-fat diet and be monitored for several months.
Birmingham, AlabamaAges 18–65 - NCT06751589RecruitingEarly Phase 1
Weight loss drug study for people with endometrial cancer
This study tests if adding a weight loss medication (tirzepatide or semaglutide) during chemotherapy helps people with early-stage endometrial cancer who are overweight or have diabetes. It aims to see if weight loss can improve treatment outcomes.
Basking Ridge, New JerseyAges 18 years+ - NCT06759701RecruitingEarly Phase 1
Weight loss drug before prostate cancer surgery pilot study
This study tests if taking tirzepatide (a weight loss medicine) before prostate removal surgery is safe and helpful for overweight men with intermediate-risk prostate cancer. It aims to see if losing weight can improve surgery outcomes.
Houston, TexasAges 18 years+ - NCT06795386Recruiting
Widespread pain after rapid weight loss in Black and Hispanic adults
This study looks at whether rapid weight loss from bariatric surgery leads to long-term widespread pain in Black and Hispanic adults. The goal is to understand how weight loss affects pain and find better ways to help people manage it.
New York, New YorkAges 18–75 - NCT06811324RecruitingPhase 2
Tirzepatide for muscle and vessel health in older adults
This study tests if the drug tirzepatide can improve muscle and blood vessel health in older adults with obesity. You may be eligible if you are 50 or older, have a BMI between 30 and 40, and do not have diabetes.
San Antonio, TexasAges 50 years+
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Common questions
- Are there clinical trials for weight loss?
- Yes. Clin2 currently lists 194 recruiting weight loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weight loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weight loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.