Clinical trials
Weight Loss clinical trials
Below are recruiting weight loss clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07423065Recruiting
Continuous glucose monitor for prediabetes and weight loss
This study tests whether wearing a continuous glucose monitor (a small sensor on your skin that tracks your blood sugar) can help people with prediabetes and obesity better control their blood sugar and lose weight. You will be asked to wear the device for several days to see how your glucose levels change throughout the day.
IzolaAges 18–70 - NCT07402031Recruiting
Predicting weight loss from obesity treatments
This study looks at how people lose weight after medication or surgery for obesity. It helps predict which treatment might work best for you.
Brussels, Brussels CapitalAges 18–65 - NCT07393360Recruiting
Muscle preservation during weight loss with GLP-1 drugs
This trial tests a special medical food to help keep muscle mass while losing weight with GLP-1 medications like liraglutide, semaglutide, or tirzepatide. It's for adults with obesity or overweight with related health issues.
MilanAges 18–65 - NCT07387796Recruiting
Brain and behavior changes with tirzepatide stop and restart
This study looks at how your brain and behavior change when you stop and then restart the weight loss drug tirzepatide. It will help researchers understand what happens during treatment breaks.
Dallas, TexasAges 18–70 - NCT07387393Enrolling by invitation
PILI Pasifika Lifestyle Program for Native Hawaiian and Pacific Islander adults
This study tests a 3-month lifestyle program called PILI Pasifika, which includes healthy eating, physical activity, and support for social needs like housing or food. It aims to help Native Hawaiian and Pacific Islander adults with conditions like diabetes or high blood pressure improve their health in real-world settings.
Fayetteville, ArkansasAges 18 years+ - NCT05942287Recruiting
Weight and weight loss study in heart failure with weak pumping
This study looks at how obesity and weight loss affect people living with heart failure where the heart pumping strength is reduced. It uses heart imaging (MRI) to measure the heart and may help clarify what weight changes do for symptoms and heart function.
Jersey, JerseyAges 18–85 - NCT07368777Recruiting
Genetics-based diet counseling vs standard diet for weight loss
This trial compares two types of diet counseling—one based on your genetic makeup and the other standard advice—to see which helps more with weight loss and reducing body fat. It is for adults who are overweight or obese and willing to follow a diet program.
MarousiAges 18–65 - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT07320287Recruiting
Probiotics for babies born by C-section
This trial tests whether a multi-strain probiotic supplement can help with growth, digestion, and gut health in healthy full-term babies who were born by C-section.
HanoiAges birth–1 day - NCT07315659Recruiting
Time-restricted eating for weight loss maintenance in obesity
This study tests whether eating only during a set window of hours each day can help people with obesity keep weight off after losing it. You would follow a specific meal schedule and get all your food provided for a period.
Granada, GranadaAges 18–70 - NCT07297290RecruitingPhase 3
Testing Metformin for Weight Loss in Obesity
This trial tests whether metformin, a common diabetes medicine, can help people with obesity lose weight. It is for people who do not have diabetes and have not used weight loss treatments in the past year.
Enugu, Enugu StateAges 20–59 - NCT07302802Recruiting
Semaglutide for weight loss in teens with genetic obesity
This trial studies whether semaglutide (a once-weekly injection) helps adolescents with a specific genetic form of obesity lose weight. It is for teens who are already being prescribed semaglutide as part of their regular care.
ParisAges 12–21 - NCT07292441RecruitingPhase 3
Long-term weight loss study for trial participants
This study is for people who finished a previous weight loss trial and want to continue treatment with an injectable medication GZR18. It tests how well the medicine works over a longer period.
Beijing, Beijing MunicipalityAges 18–75 - NCT07280221Enrolling by invitation
Wegovy real-world weight loss study in Korea
This study tracks how well Wegovy (a once-weekly injection for weight loss) works for people in Korea who are just starting the medication. It helps doctors understand real-world results outside of a research clinic.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT07276815Recruiting
OverStitch NXT endoscopic suturing study for obesity
This study tests a new device called the OverStitch NXT system, which is used during an endoscopic sleeve gastroplasty to help people with obesity lose weight by reducing the size of the stomach without surgery. It is for people who meet specific BMI requirements and are committed to making lasting diet changes.
Beijing, China/BeijingAges 18 years+ - NCT07234916Enrolling by invitation
Multivitamins for people starting weight-loss injections
This trial tests whether a multivitamin can help people on the weight-loss injection Tirzepatide maintain healthy vitamin levels. If you're using this injection and meet the other criteria, you may join.
AmersfoortAges 18–70 - NCT07237750Recruiting
Weight loss trial: endoscopy procedure vs lifestyle changes
This study compares a new endoscopic procedure (a stomach tightening treatment done through a tube in your mouth) with a structured diet and exercise program to help with weight loss. It is for Asian adults who have tried and failed to lose weight before.
Beijing, Beijing MunicipalityAges 18–65 - NCT07223242RecruitingPhase 2/Phase 3
Tailored exercise training for heart failure with preserved pumping strength
This trial tests a personalized exercise program to help people with a type of heart failure called HFpEF. You may qualify if your heart still pumps well but you have trouble being active, and you are willing to use a phone app and exercise regularly.
Dallas, TexasAges 18 years+ - NCT07213466RecruitingPhase 4
Personalized weight-loss medication for bipolar disorder
This study wants to see if a personalized approach with FDA-approved weight-loss medications can help people with bipolar disorder who are overweight or have obesity, while staying on their mood stabilizer treatment. It might be a good fit if you have bipolar disorder and struggle with your weight.
Rochester, MinnesotaAges 18–65 - NCT07195708Recruiting
Orbera365 Balloon for Weight Loss
This trial tests an intragastric balloon (Orbera365) to help people with obesity lose weight. The balloon is placed in your stomach for up to 12 months. The study will see if it is safe and effective when combined with diet and behavior changes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07178704Recruiting
Genes and metabolism after weight loss surgery
This study looks at how your genes and metabolism affect changes in body composition after weight loss surgery. It aims to understand why some people lose more weight or gain muscle differently than others.
Galveston, TexasAges 18–65 - NCT07165431Recruiting
Postbiotic supplement study for overweight and obesity
This study tests whether taking a daily postbiotic gummy for 12 weeks can improve body composition and metabolic health in people with overweight or obesity. It may help if you have stable weight and no major health conditions like diabetes.
Pamplona, NavarreAges 18–70 - NCT07163650RecruitingPhase 4
Obesity medication 6 months after weight-loss surgery
This trial is for people who had metabolic surgery 6 months ago and still have a BMI of 28 or higher. It tests whether an anti-obesity medication can help with further weight loss after surgery.
Nanjing, JiangsuAges 18–55 - NCT07144800Recruiting
Healthy eating and activity program for Hispanic families
This study tests a program to help Hispanic families with overweight or obesity eat healthier and be more active. It focuses on parents and their children aged 8-12, and may help improve family health.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for weight loss?
- Yes. Clin2 currently lists 181 recruiting weight loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weight loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weight loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.