Clinical trials
Young Adult Cancer clinical trials
Below are recruiting young adult cancer clinical trials, each written for real people, not researchers. We’re tracking 140 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06561074RecruitingPhase 2
Study of calaspargase, decitabine, and venetoclax for young T-cell cancer
This trial tests a combination of three drugs (calaspargase, decitabine, and venetoclax) for children, teens, and young adults with T-cell leukemia or lymphoma that has come back or not responded to treatment. The goal is to see if this combination can help destroy cancer cells.
Houston, TexasAges 1 month–21 years - NCT04621201Recruiting
Testing tumor genetics in young people with bone sarcomas
This study looks at the genetic (DNA) features of tumors in children, teens, and young adults with osteosarcoma, Ewing sarcoma, or synovial sarcoma. It may help researchers better understand these cancers by analyzing a fresh tumor sample and a blood sample.
Torino, TurinAges Up to 24 years - NCT06305910RecruitingPhase 1
Vaccine immunotherapy for recurrent brain tumors or newly diagnosed DIPG
This trial tests a combination of a vaccine made from tumor cells and a drug that may boost the immune system's ability to fight brain tumors. It is for children and young adults with a recurrent high-grade glioma or a newly diagnosed diffuse midline glioma with a specific genetic marker (H3K27M).
Minneapolis, MinnesotaAges 2–25 - NCT05310591RecruitingPhase 1/Phase 2
Study anti-PD1 treatment with Kymriah re-dosing for leukemia
This Phase 1/2 trial studies giving an anti-PD1 antibody (like pembrolizumab or nivolumab) along with a second Kymriah (tisagenlecleucel) infusion in children and young adults whose B-cell leukemia is coming back or their Kymriah effect has faded. It may help the new immune treatment work better after the first Kymriah.
BordeauxAges 1–25 - NCT06265246Recruiting
Milk and yogurt for stronger bones in young adults
This study tests whether adding milk and yogurt to your diet can improve bone health and body composition. If you're a young adult with low calcium intake, you may qualify to join.
Saskatoon, SaskatchewanAges 19–30 - NCT07616934RecruitingPhase 1
Safety and immune response study of VAX-A1 vaccine in healthy young adults
This study tests a new vaccine called VAX-A1 in healthy people aged 18–40 to see if it's safe and if it helps the body build protection against Group A Streptococcus (a bacteria that can cause serious infections). You'll receive two vaccine doses and have blood tests and heart monitoring over 6 months.
Adelaide, South AustraliaAges 18–40 - NCT06692868Recruiting
Fertility protection for young cancer patients
This trial offers fertility preservation options for children, teens, and young adults diagnosed with cancer or undergoing stem cell transplant before age 21, to help protect their ability to have biological children in the future.
Ulm, Baden-WurttembergAges Any age - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT07205926RecruitingPhase 1
Testing a new Shigella vaccine in healthy adults
This trial tests a new Shigella vaccine in healthy adults to see if it is safe and creates a good immune response. It is a first-in-human study, meaning this is the first time the vaccine is given to people.
Cincinnati, OhioAges 18–49 - NCT06932432Recruiting
Psychological support study for young adults with chronic pain
This study tests a new approach to psychological support for young adults (ages 18-25) with chronic pain that started in childhood. It uses daily surveys on your smartphone to adjust support based on what you need day to day.
Seattle, WashingtonAges 18–25 - NCT07174661Recruiting
Planning ahead for teens and young adults with advanced cancer
This study tests an educational tool to help young adults with advanced solid tumors or high-grade brain tumors think about and discuss their future healthcare wishes early. It may help you feel more prepared and in control of your care.
Scottsdale, ArizonaAges 18–39 - NCT07177417RecruitingPhase 4
How the immune system responds to FluMist in the airways
This study tests how the immune system in your nose and airways responds to the FluMist nasal spray flu vaccine. It may help doctors understand why some people get better protection from the flu.
St Louis, MissouriAges 18–40 - NCT07167225Recruiting
Chemical exposure in young adults who use e-cigarettes and cannabis
This study looks at how young adults who use e-cigarettes, cannabis, or both are exposed to harmful chemicals. It aims to understand the health effects of using these products together.
Buffalo, New YorkAges 18–25 - NCT07089121RecruitingPhase 1/Phase 2
Descartes-08 for young people with autoimmune diseases
This trial tests a new therapy called Descartes-08 for children, teens, and young adults with autoimmune conditions like lupus, myasthenia gravis, or dermatomyositis. It aims to see if it can help control moderate disease that hasn't responded well enough to other treatments.
Washington D.C., District of ColumbiaAges 12 years+ - NCT07049783Recruiting
How exercise timing affects blood pressure response
This study looks at how the time of day you exercise affects your blood pressure response. It is for young adults with slightly elevated blood pressure who are generally healthy, not on certain medications, and do not have sleep or chronic health issues.
Newark, DelawareAges 18–39 - NCT07043920Recruiting
Smoking and physical activity in young adults
This study looks at how smoking affects physical activity levels in healthy young adults who are studying health sciences. It may help you understand if smoking changes your daily movement.
IstanbulAges 18–30 - NCT06961591Recruiting
Cooking skills for long-term weight loss in young adults with ID
This program teaches cooking skills to help young adults with intellectual disabilities lose weight and keep it off for 2 years. You’ll learn to prepare healthier meals with support from a family member or caregiver.
Kansas City, KansasAges 18–35 - NCT06913985Enrolling by invitation
Study on heart health in teens and young adults
This study looks at how fitness, sleep, and diet during childhood affect heart and metabolic health in teenagers and young adults. It uses data and samples already collected from participants in earlier studies.
Little Rock, ArkansasAges 13–21 - NCT06914479RecruitingPhase 1
Gene therapy and valacyclovir for recurrent brain tumors in young people
This trial tests a new gene therapy that uses two special viruses and an oral antiviral drug (valacyclovir) to treat brain tumors that have come back in children and young adults. The therapy is given right after surgery to remove the tumor, with the goal of helping your immune system fight the cancer.
Ann Arbor, MichiganAges 3–39 - NCT06897137Recruiting
Improving quality of life measurement in young cancer survivors
This study aims to better understand how cancer affects the quality of life of teens and young adults (ages 15–39). You will fill out questionnaires about your physical and emotional well-being.
Winston-Salem, North CarolinaAges 15 years+ - NCT06709495RecruitingPhase 1/Phase 2
PEEL-224 with chemo for teens and young adults with sarcoma
This trial tests a new drug called PEEL-224 combined with two chemotherapy drugs (vincristine and temozolomide) for people ages 12 to 49 with sarcoma that has come back or hasn't responded to standard treatments. The goal is to see if this combination is safe and effective.
Boston, MassachusettsAges 12–49 - NCT06519682Recruiting
Immunotherapy for young people with a specific brain tumor
This trial is testing a new immunotherapy (nivolumab) for children, teens, and young adults with a specific type of aggressive brain tumor (glioblastoma that has a DNA repair problem). It aims to see if giving this treatment early, right after surgery, can help the immune system fight the tumor.
Toronto, OntarioAges 1–25 - NCT06454344Recruiting
Sleep and childhood experiences study in young adults
This study looks at how sleep is affected by tough childhood experiences. It tests whether changing sleep patterns can help young adults who have had these experiences and currently have poor sleep.
Iowa City, IowaAges 18–29 - NCT06383338RecruitingPhase 1
Metabolism Changes in Young People with Lymphoma
This study looks at how your body's metabolism (processing of food and medicine) changes after you start treatment for lymphoma. It uses two safe, commonly used drugs (omeprazole and dextromethorphan) to measure these changes.
Melbourne, VictoriaAges 6–25
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Common questions
- Are there clinical trials for young adult cancer?
- Yes. Clin2 currently lists 140 recruiting young adult cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a young adult cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a young adult cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.