Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07352813Recruiting
Comparing numbing methods for kids with MIH teeth
This study tests two ways to numb teeth—in the bone or in the gum—to see which works better for children with weak enamel on their back teeth and front teeth. It may help find a pain-free way to treat these teeth.
AnkaraAges 6–12 - NCT07360886Recruiting
Early detection of brain conditions in active drivers
This study looks at how well doctors can spot early signs of certain brain conditions in people who drive. You may join if you have a valid license, are between 18 and 85, and have one of the neurological diagnoses the study is focusing on.
Olomouc, Olomouc RegionAges 18–85 - NCT07356245RecruitingPhase 2
Ruxolitinib after stem cell transplant for T-cell lymphoma
This trial tests whether taking ruxolitinib after a stem cell transplant can help prevent T-cell lymphoma from coming back. It is for patients whose lymphoma is in remission (partial or complete) after their transplant.
Columbus, OhioAges 18 years+ - NCT07358000Recruiting
Comparing two moisturizers for mild to moderate eczema
This trial tests if two different moisturizing balms work equally well for treating mild to moderate eczema (atopic dermatitis) in children and adults. It may help find a more affordable or better-tolerated option.
Caen, NormandyAges Any age - NCT07355972RecruitingEarly Phase 1
CT1195E cell therapy for progressive scleroderma
This trial tests a new cell therapy called CT1195E for people with refractory or progressive systemic sclerosis (scleroderma) that also affects the lungs. It aims to see if the treatment is safe and can help slow or stop the disease.
Wuhan, HubeiAges 18–60 - NCT07359430Recruiting
Deep phenotyping of chronic inducible urticaria
This study aims to better understand inducible urticaria (hives triggered by cold, pressure, or friction) and chronic spontaneous urticaria. Researchers will use skin tests to measure how different triggers affect your skin in detail.
Leiden, South HollandAges 18 years+ - NCT07355699RecruitingPhase 4
Orelabrutinib for untreated marginal zone lymphoma
This trial tests a new targeted drug (orelabrutinib) with or without another drug that targets CD20 (a protein on some immune cells) for people with untreated marginal zone lymphoma. It aims to see if this combination works better than other treatments and may be an option for those who cannot have radiation.
BeijingAges 18 years+ - NCT07359183Recruiting
Long-term follow-up of kids who had oral immunotherapy for allergies
This study checks on children and young people 5 to 15 years after they finished an 18-month oral immunotherapy treatment for peanut, egg, or milk allergy. It helps researchers understand how their allergies and health are doing over the long term.
Parkville, VictoriaAges Any age - NCT07353840Recruiting
Personalized treatment for T-cell lymphoma after first complete remission
This trial tests if giving a tailored treatment after first complete remission can improve outcomes for certain types of peripheral T-cell lymphoma. It is for people who have finished initial standard chemotherapy with a complete response.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07361029RecruitingPhase 1
CAR T cell therapy for adults with returning B-cell leukemia
This trial tests whether specially designed immune cells (CAR T cells) that target CD19 can help adults whose B-cell acute lymphoblastic leukemia has not responded to standard treatments or has returned. The cells are made from your own blood and given back to you after a short chemotherapy preparation.
Riyadh, Riyadh RegionAges 18–75 - NCT07358234Enrolling by invitationEarly Phase 1
Comparing two EoE treatments on esophagus widening
This study compares two medicines—Eohilia (an oral steroid) and Dupixent (an injectable biologic)—to see which one better helps widen the esophagus in people with eosinophilic esophagitis (EoE). It may help you if you have active EoE and are looking for a new treatment option.
Scottsdale, ArizonaAges 18 years+ - NCT07356310Recruiting
Body scan and breathing test for airway health
This trial uses a special breathing test to measure how your airways react. It helps doctors understand airway tone and reactivity, which may relate to conditions like asthma.
Rochester, New YorkAges 18 years+ - NCT06849622Recruiting
Blood spot test for type 1 diabetes and celiac disease
This study tests a new way to check for type 1 diabetes and celiac disease using a tiny drop of blood from a finger prick, instead of a regular blood draw. The goal is to make diagnosis easier and less scary for children.
Florence, ItalyAges 2–13 - NCT06850311RecruitingPhase 2/Phase 3
Herbal ointment for mild to severe eczema
This trial tests whether a special herbal ointment can help treat atopic dermatitis (eczema). It is for adults with mild, moderate, or severe eczema covering less than 10% of their body surface. The ointment is applied directly to the skin, and participants will also use a gentle, fragrance-free moisturizer.
New Taipei CityAges 18–65 - NCT06850285Recruiting
CD30 CAR-T for relapsed or refractory CD30+ lymphoma
This trial tests a new type of immunotherapy called CD30 CAR-T cells for people with CD30-positive lymphoma that has come back or hasn't responded to other treatments. The treatment uses your own immune cells that are specially trained to find and kill lymphoma cells carrying the CD30 marker.
Taiyuan, ShangxiAges 15–80 - NCT06174922RecruitingPhase 3
Comparing steroid, antifungal, or both for ABPA
This trial compares three treatments for ABPA: a steroid (prednisolone), an antifungal (itraconazole), or both together. It aims to find which works best for controlling symptoms and preventing flare-ups.
Chandigarh, ChandigarhAges 18 years+ - NCT06170489RecruitingPhase 3
Study of JS004 plus toripalimab for Hodgkin lymphoma
This study tests a new combination of two drugs (JS004 plus toripalimab) versus standard chemotherapy for people with Hodgkin lymphoma that no longer responds to PD-1/PD-L1 immunotherapy. The goal is to see if the new combination works better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06503237Recruiting
SWK002 for tough-to-treat rheumatoid arthritis
This trial tests a new treatment called SWK002 for people with rheumatoid arthritis that hasn't improved after trying multiple medications. It aims to see if SWK002 can help when other treatments have failed.
Changsha, HunanAges 18 years+ - NCT06852911Recruiting
New FeNO device for asthma diagnosis
This study tests a new device that measures a lung marker called FeNO (fractional exhaled nitric oxide) to help diagnose asthma. It may be an option for adults with asthma who have not changed their medication recently and have no recent infections.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+ - NCT06685744Recruiting
Tele-rehab for Parkinson's or MS
This trial tests if a home-based tele-rehabilitation program helps people with Parkinson's disease or multiple sclerosis. It aims to improve movement and daily life through guided remote sessions.
BariAges 25–85 - NCT06849882Recruiting
Balance test study for people with multiple sclerosis
This study will test whether a simple balance test (the Dubousset Functional Test) is reliable and accurate for people with MS. If you have mild disability and can stand without help, you may be able to join.
Kayseri, KayseriAges 18–65 - NCT06853834Recruiting
Comparing two biopsy methods for suspected sarcoidosis
This trial compares two ways of taking a lung tissue sample (cryo biopsy vs forceps biopsy) in people who may have sarcoidosis. The goal is to see which method is better at diagnosing the condition.
Lucknow, Uttar PradeshAges 18 years+ - NCT00874783Recruiting
Testing nerve-cell growth from donated body cells
This trial uses donated body cells or small hair samples from people with neurological diseases (and healthy donors) to try to grow “nerve-like” cells for research. It may help scientists learn how to better study and treat different neurological conditions.
Jerusalem, IsraelAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.