Treatment
Comparator clinical trials
We’re tracking 1,699 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT06713616RecruitingPhase 3
Esketamine vs. ketamine for hard-to-treat depression
This study compares the effectiveness of esketamine (Spravato) and another similar drug, ketamine, for adults with major depression that has not improved after trying at least two other antidepressants. It aims to find out which treatment works better.
Milford, ConnecticutAges 18 years+ - NCT06705062RecruitingPhase 3
Reduced vs standard GVHD prevention in stem cell transplant
This trial tests whether a lower dose of a common drug (cyclophosphamide) after transplant can prevent graft-versus-host disease (a complication where donor cells attack your body) just as well as the standard dose. It also uses another medicine (anti-thymocyte globulin) after the transplant to help protect you.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT06713330Recruiting
Stainless steel vs. resin crowns for baby molars
This study compares two types of dental crowns (stainless steel vs. resin) for baby molars to see which works better. If your child needs full mouth dental work under general anesthesia, they may be able to join.
Cincinnati, OhioAges 2–5 - NCT06706375Recruiting
Comparing two types of penile nerve blocks for child circumcision
This study tests two ways of numbing the penis before circumcision in children. The goal is to see which method works better and causes less discomfort.
Lausanne, Canton of VaudAges Up to 17 years - NCT06705829Recruiting
Comparing blood clotting tests for clotting factor deficiencies
This trial compares different blood test reagents to see which works best for measuring clotting time in people with clotting factor deficiencies or liver disease. It may help doctors choose the right test for your condition.
StrasbourgAges 18 years+ - NCT05873777Recruiting
PET/CT scans to compare two tracers in FAP or SSTR2-positive cancer
This study compares two special PET/CT scan tracers—68Ga-FAPI-LM3 and 18F-FDG—to see how well they detect cancer that shows FAP or SSTR2 signals. It may help doctors choose better imaging to find or assess certain tumors.
Xiamen, FujianAges 18 years+ - NCT05944913Recruiting
Testing a special wound dressing after sarcoma tumor removal
This trial compares two types of wound dressings after surgery for soft-tissue sarcoma (STS) that has had radiation therapy. It aims to see whether one dressing helps your wound heal better after tumor removal.
Nantes, Pays de LoireAges 18 years+ - NCT06700681Enrolling by invitation
Comparing two sedatives for heart ablation procedures
This trial compares two sedative medicines (remimazolam and propofol) given during heart ablation procedures. The study uses brain-wave monitoring to see which medicine provides better sedation and recovery. It's for people who are already scheduled for this procedure with a specific doctor.
TaipeiAges 20–80 - NCT06704672Recruiting
Effect of a new glucose sensor on blood sugar control in diabetes
This study compares a continuous glucose monitor (CGM) to fingerstick testing for people with type 1 or type 2 diabetes who give themselves insulin injections. It aims to see if using the sensor helps increase the time blood sugar stays in a healthy range.
GdanskAges 18 years+ - NCT06700096RecruitingPhase 3
Testing a new drug for adults with severe hemophilia B
This trial tests a single dose of ANB-002, an experimental therapy for hemophilia B. It aims to see if the drug is safe and effective for people with severe hemophilia B who have been treated with factor IX before and do not have inhibitors.
ChelyabinskAges 18 years+ - NCT06696989Enrolling by invitation
Balance and core exercises for children with cerebral palsy
This study compares two types of exercises—Frenkel's exercises and core stability exercises—to see which helps children with ataxic cerebral palsy improve their balance and movement. The goal is to find the best way to help your child stand, sit, and move more safely.
Lahore, Punjab ProvinceAges 6–12 - NCT06685575Enrolling by invitation
Comparing two types of back surgery for leg pain
This trial compares a newer, less invasive surgery (endoscopic foraminotomy) to a traditional back surgery for people with leg pain caused by a narrowed spine canal. The goal is to see which approach provides better relief and recovery.
Chon Buri, Changwat Chon BuriAges 30–80 - NCT06688578Recruiting
Can a device that makes small noises improve balance and walking?
This study tests whether a device that plays small, random sounds (called stochastic noise) can help people feel steadier and walk better. It is for healthy adults of two age groups — those 60 and older, and those 21–59.
Baltimore, MarylandAges 21 years+ - NCT06693258Recruiting
Robotic vs. open thyroid surgery comparison study
This study compares two ways to remove the thyroid gland: a newer robotic method through the armpit (transaxillary robotic thyroidectomy) versus the traditional open surgery through a neck incision. It aims to see which approach leads to better recovery and fewer complications.
ParisAges 18 years+ - NCT06686680Recruiting
Shockwave therapy for knee arthritis after ACL repair
This study tests whether shockwave therapy can help knee pain and function in people who developed knee osteoarthritis after an ACL reconstruction. If you had ACL surgery at least a year ago and still have knee pain, this treatment might offer a new option without surgery.
Cambridge, MassachusettsAges 18–55 - NCT06684379RecruitingPhase 1/Phase 2
Two Doses of PRS CK STORM for Severe Viral Pneumonia
This study tests a new drug called PRS CK STORM to see if it can safely calm the body's overactive immune response (cytokine storm) in people with severe pneumonia from COVID-19, flu, or RSV who need oxygen. It aims to reduce inflammation and improve recovery.
Alcalá de Henares, MadridAges 18 years+ - NCT06682169RecruitingPhase 3
New pill for chronic graft-versus-host disease after other treatments fail
This trial tests a new pill called rovadicitinib for chronic GVHD that has not improved after 2 to 5 other treatments. It compares the new drug to one chosen by your doctor from a list of approved options.
Hefei, AnhuiAges 18–70 - NCT06672146RecruitingPhase 2
New treatments for AML with an IDH2 mutation
This trial tests new treatments for people with newly diagnosed acute myeloid leukemia (AML) that has a change in the IDH2 gene. It aims to find a better option for those who cannot have standard high-dose chemotherapy.
Tucson, ArizonaAges 18 years+ - NCT06671483RecruitingPhase 3
Zasocitinib for psoriatic arthritis without prior biologic use
This trial tests an oral medication called zasocitinib for adults with psoriatic arthritis who have not tried biologic medicines before. It aims to see if the drug can improve joint pain, swelling, and skin symptoms.
Chandler, ArizonaAges 18 years+ - NCT06671015Recruiting
Comparing breathing support methods after a breathing tube is removed in people with heart failure
This study compares two types of breathing support—a high-flow nasal cannula and noninvasive ventilation—to see which one better prevents the need for re-inserting a breathing tube in people with systolic heart failure who are at high risk for breathing problems after the tube is removed.
New Haven, ConnecticutAges 18 years+ - NCT06674187Recruiting
Comparing stoma hernia prevention in colostomy surgery
This trial tests whether sewing the belly lining in a special way during colostomy surgery can lower the chance of a hernia near the stoma. It may help you if you need a colostomy and are in generally good health.
Nanjing, JiangsuAges 18–75 - NCT06676644Recruiting
Flu vaccine with booster for older adults with health conditions
This trial tests whether a flu vaccine with an extra ingredient (called an adjuvant) is safer and works better for older Asian adults with chronic health conditions than a standard flu vaccine. It aims to provide better protection against the flu for people like you.
TaipeiAges 65 years+ - NCT06671002RecruitingPhase 4
Pain medicine safety study for kids having surgery
This study compares different pain medicines to see which works best and is safest for children after surgery for tonsil removal, gallbladder removal, or knee arthroscopy. It aims to help find the most effective and least risky pain control option.
Los Angeles, CaliforniaAges 12–20 - NCT06664775RecruitingPhase 3
Comparing two bleeding-control patches during open surgery
This study tests a special patch called TachoSil against a standard surgical pad (Surgicel) to see which works better for controlling minor oozing during open abdominal, chest, or pelvic surgeries. It may be an option if you are having certain types of surgery and have a small area of mild bleeding that needs help to stop.
Torrance, CaliforniaAges 1 month+
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,699 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.