Treatment
Levothyroxine clinical trials
We’re tracking 19 recruiting studies that include Levothyroxine, each written for real people, not researchers, below.
Recruiting studies
- NCT06428097RecruitingPhase 1
Thyroid hormone before heart transplant
This study tests whether giving a thyroid hormone supplement called levothyroxine before a heart transplant can help with recovery. It is for people already listed for a heart transplant who do not have thyroid problems.
San Francisco, CaliforniaAges 18 years+ - NCT06652113Recruiting
Hydroxychloroquine with thyroid hormone for recurrent pregnancy loss
This study tests whether a combination of hydroxychloroquine (an anti-inflammatory drug) and levothyroxine (thyroid hormone) can improve live birth rates in women with recurrent pregnancy loss, normal thyroid function, and TPO antibodies.
Guangzhou, GuangdongAges 20–40 - NCT07393165Recruiting
Thyroid hormone therapy for children with mild thyroid issues
This trial tests whether a thyroid hormone medication (levothyroxine) can improve heart function in children who have slightly high TSH levels but normal thyroid hormones. It may help children aged 4 to 15 with subclinical hypothyroidism.
Tanta, El-GharbiaAges 4–15 - NCT07332273RecruitingPhase 3
Levothyroxine for weight loss in obesity
This trial tests whether adding levothyroxine (a thyroid hormone) to a low-calorie diet helps people with obesity lose more weight. It is for adults aged 25-60 with a BMI of 30-39.9 who have either mild underactive thyroid or normal thyroid but higher thyroid hormone levels in the normal range.
CadizAges 25–60 - NCT07380854Recruiting
Thyroid Hormone After Heart Bypass for Mild Underactive Thyroid
This study looks at whether giving thyroid hormone replacement to people with mild underactive thyroid (subclinical hypothyroidism) after heart bypass surgery improves their recovery. It is for adults who are scheduled for bypass surgery and have not recently used thyroid or anti-thyroid medications.
Seongnam-siAges 19–90 - NCT07733375Recruiting
Smart wristband study for thyroid hormone therapy after surgery
This trial tests whether a smart wristband can help monitor thyroid hormone replacement after total thyroidectomy. It may make follow-up easier and more convenient for patients.
Istanbul, KadıköyAges 18 years+ - NCT03977207Recruiting
Thyroid hormone supplement for people on dialysis
This trial tests whether taking a thyroid hormone supplement helps people who are on hemodialysis and have borderline-high thyroid lab results (high TSH but normal FT4). It’s studying whether treatment changes thyroid-related outcomes or health while on dialysis.
Orange, CaliforniaAges 18–75 - NCT05276856Recruiting
Study of recovery in secondary hypothyroidism with thyroid pills
This trial looks at how people with secondary hypothyroidism recover while taking T4 replacement therapy (thyroid hormone medicine). It may help doctors understand what recovery rates to expect and who might benefit from specific management.
HalifaxAges 18 years+ - NCT05316922RecruitingPhase 3
Lowering thyroid hormone during radiation to prevent low thyroid
This study tests whether using treatment to keep thyroid-stimulating signals low during radiation to the thyroid area can help prevent a treatment-related drop in thyroid function in children. It is aimed at kids with certain cancers whose radiation plan includes thyroid tissue.
MilanAges Any age - NCT06041204Recruiting
Thyroid hormone plus letrozole for PCOS and mild hypothyroidism
This trial tests whether adding a low-dose thyroid hormone (levothyroxine) to the standard fertility treatment letrozole improves pregnancy rates in women with both PCOS and mild hypothyroidism. It may help if you have trouble getting pregnant and have these two conditions.
CairoAges 20–40 - NCT06073665RecruitingPhase 4
Thyroid hormone dosing in older adults
This study tests whether current thyroid medication doses are appropriate for people aged 65 and older. The goal is to find the best dose for each person to improve well-being.
Philadelphia, PennsylvaniaAges 65 years+ - NCT06083636Recruiting
Better lab tests for people with hypothyroidism on levothyroxine
This study aims to improve lab tests for people with hypothyroidism who take levothyroxine. It compares their test results to healthy volunteers to see if doctors can make more accurate diagnoses.
Amsterdam, North HollandAges 18–100 - NCT06345339RecruitingPhase 2/Phase 3
Comparing Armour Thyroid to synthetic T4 for hypothyroidism
This study is testing whether Armour Thyroid (a natural pig-derived thyroid hormone) works as well as synthetic T4 (levothyroxine) for people with hypothyroidism. If you are already on a stable dose of levothyroxine, you may be able to switch to Armour Thyroid and see how it compares.
Birmingham, AlabamaAges 18–75 - NCT06455371Recruiting
Personalized Levothyroxine Dosing After Thyroid Removal
This study tests a personalized way to dose levothyroxine (thyroid hormone) after total thyroid removal. It aims to find the right dose for each patient, improving energy and well-being.
BergenAges 18 years+ - NCT06724224Recruiting
Comparing thyroid hormone drugs for babies with low thyroid
This study compares two types of levothyroxine (a thyroid hormone medicine) to see which works better for newborns and children with congenital hypothyroidism (a condition where the thyroid gland doesn't work properly from birth). If your child was diagnosed early and lives in the Emilia-Romagna region of Italy, this trial may help find the best treatment.
Bologna, BolognaAges Up to 11 years - NCT06731764RecruitingPhase 2/Phase 3
New ways to treat hypothyroidism
This study tests a new approach for people with hypothyroidism who are already taking levothyroxine. You may be able to join if you are on a certain dose and do not have other health conditions that could affect the results.
Farmington, ConnecticutAges 18 years+ - NCT07257250Recruiting
Levothyroxine for IVF in women with mild thyroid issues
This study tests whether taking levothyroxine (a thyroid hormone medication) before IVF or ICSI with frozen embryo transfer improves pregnancy rates in women with subclinical hypothyroidism (a mild thyroid condition). It aims to see if this treatment helps women like you have a better chance of getting pregnant.
Ho Chi Minh City, Ho Chi MinhAges 18–45 - NCT07421869Recruiting
Recovery from immune therapy-related hypothyroidism
This trial looks at whether patients can recover from low thyroid function caused by immune checkpoint inhibitor drugs. If you've finished immune therapy and are on thyroid medication, you may be able to stop or reduce it.
Seongnam-siAges 19 years+ - NCT07568574Enrolling by invitation
Medical Study of Performance-Enhancing Substances in Elite Athletes
This study looks at how medically supervised performance-enhancing substances affect elite athletes' health and quality of life. Participants must be retired from professional sports and willing to undergo careful medical monitoring throughout the trial.
Abu DhabiAges 18 years+
What Levothyroxine is being studied for
Conditions with recruiting Levothyroxine studies.
Common questions
- Are there clinical trials studying Levothyroxine?
- Yes. Clin2 currently lists 19 recruiting studies that include Levothyroxine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Levothyroxine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Levothyroxine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Levothyroxine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.