Treatment
Low Dose clinical trials
We’re tracking 457 recruiting studies that include Low Dose, each written for real people, not researchers, below.
Recruiting studies
- NCT06427694Recruiting
Long-Term Follow-Up of Low-Dose IL-2 After Heart Attack
This study is checking on people who finished a previous trial (IVORY) that tested a low-dose treatment called IL-2 for reducing inflammation after a heart attack. It will see how they are doing over time and if the treatment helped their heart health.
Cambridge, CambridgeshireAges 18–85 - NCT06442475RecruitingPhase 2
Low-dose mosunetuzumab for untreated indolent B-cell lymphoma
This trial tests a low dose of the drug mosunetuzumab for people with slow-growing B-cell lymphomas (follicular lymphoma or marginal zone lymphoma) who have not had any previous treatment. It aims to see if this drug can help control the disease with fewer side effects.
Seattle, WashingtonAges 18 years+ - NCT06444919RecruitingPhase 4
Capsaicin patch for finger osteoarthritis with nerve pain
This study tests if a capsaicin patch (a hot pepper extract) can reduce finger pain in people with osteoarthritis who also have nerve-like pain. It's for those who haven't gotten enough relief from standard painkillers.
Clermont-FerrandAges 18 years+ - NCT06484829RecruitingPhase 1/Phase 2
New drug combo for relapsed or refractory multiple myeloma
This trial tests a new drug, purinostat mesylate, combined with pomalidomide (a chemotherapy pill) and a low-dose steroid (dexamethasone) for people with multiple myeloma that has returned or stopped responding to prior treatments. The goal is to see if this combination can help control the cancer with manageable side effects.
Chengdu, SichuanAges 18–75 - NCT06488586Recruiting
Ketamine vs Esketamine for treatment-resistant depression
This trial compares two forms of ketamine—given by IV or as a nasal spray—in people with major depression that hasn't improved after trying at least two other antidepressants. The goal is to see which treatment works better.
Kingston, OntarioAges 18–75 - NCT06506565RecruitingPhase 4
Low-dose ketamine for burn wound pain
This trial tests a low-dose ketamine infusion during burn wound dressing changes to see if it reduces pain. It might help people who are hospitalized with a thermal burn injury.
Memphis, TennesseeAges 18 years+ - NCT06515925Recruiting
Virtual group program for managing chronic pain
This study tests a virtual group program that combines medical care with integrative approaches like mindfulness and gentle movement to help adults manage chronic musculoskeletal pain.
Malden, MassachusettsAges 18 years+ - NCT06562803Recruiting
Cleaning the blood for liver failure with sepsis
This trial tests if a special blood-filtering method combined with plasma exchange can help people with severe liver failure and sepsis. It aims to reduce inflammation and improve survival.
Guangzhou, GuangdongAges 18–70 - NCT06597565RecruitingPhase 2
ACR-368 plus low-dose gemcitabine for advanced head and neck cancer
This study tests a new combination of two drugs, ACR-368 and low-dose gemcitabine, for people with head and neck cancer that has come back or spread. The goal is to see if this treatment can help when immunotherapy or other therapies haven't worked.
Tampa, FloridaAges 18 years+ - NCT06626178Recruiting
AI for preventing smoking-related diseases
This study uses artificial intelligence to analyze CT scans and other health data to better identify people at risk for smoking-related diseases like lung cancer. Researchers hope to improve early detection and prevention.
MilanAges 18 years+ - NCT06676696RecruitingPhase 4
Stopping immunosuppression after failed kidney transplant
This study compares what happens when patients with a failed kidney transplant (still in the body) stop their immunosuppressant medicines at 6 months versus continuing them. The goal is to safely prevent your immune system from becoming too sensitive, which can make finding a new donor kidney harder.
BarcelonaAges 18 years+ - NCT05941520RecruitingPhase 2
Acolbifene vs low-dose tamoxifen to prevent breast cancer
This Phase 2 trial compares acolbifene and low-dose tamoxifen to see which better lowers breast cancer risk in premenopausal women at high risk. You would be followed with health visits, blood tests, and a breast tissue sampling procedure.
Duarte, CaliforniaAges 35 years+ - NCT06788002RecruitingPhase 2
Low-dose radiation and chemoimmunotherapy for NPC with liver spread
This trial tests a combination of low-dose radiation, chemotherapy, and immunotherapy for nasopharyngeal cancer that has spread to the liver. It aims to see if this approach can help shrink tumors and improve outcomes.
Changsha, HunanAges 18–70 - NCT06717412Recruiting
Low-dose conbercept for retinopathy of prematurity
This trial tests whether a low dose of conbercept, given as an eye injection, can safely treat type 1 ROP (an eye disease in premature babies). The goal is to stop abnormal blood vessel growth and prevent vision loss.
Xi'an, ShaanxiAges Any age - NCT06720597Recruiting
Testing a device for blood vessel health in erectile dysfunction
This study tests a device called EndoPAT to check how well the blood vessels in your penis are working. It may help doctors better understand erectile dysfunction or low testosterone.
Newport Beach, CaliforniaAges 18 years+ - NCT06765499Recruiting
Silkworm pupa powder for nutrition and frailty in motor neuron disease
This trial tests whether silkworm pupa powder can improve nutrition and reduce frailty in people with motor neuron disease (like ALS). It looks for volunteers who are frail, have a confirmed diagnosis, and are willing to provide blood, stool, and urine samples.
Hangzhou, ZhejiangAges 18–80 - NCT06789705Recruiting
MDMA for people with vasopressin deficiency
This study tests whether a low dose of MDMA, compared to a placebo, changes oxytocin levels in people with a condition called arginine vasopressin deficiency (also known as central diabetes insipidus). The goal is to understand the role of oxytocin in this condition and explore potential treatment insights.
BaselAges 18 years+ - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT06848465RecruitingPhase 1
Radiation plus chemo-immunotherapy for colon cancer with liver spread
This trial tests a combination of low-dose radiation, chemotherapy, and immunotherapy for people with colorectal cancer that has spread only to the liver. The goal is to see if this approach can shrink tumors and improve outcomes.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06852365RecruitingPhase 2
Birth control pill and resistant starch for PCOS
This trial tests whether adding a type of fiber (resistant starch) to a common birth control pill can improve health in women with PCOS. It aims to see if this combination helps with weight, hormones, and metabolism.
Philadelphia, PennsylvaniaAges 18–40 - NCT06866964RecruitingPhase 2
Aspirin to prevent blood clots in advanced germ cell cancer chemotherapy
This trial tests if daily aspirin can prevent dangerous blood clots in people receiving chemotherapy for advanced testicular or germ cell cancer. It is for those at high risk of clots and aims to improve safety during treatment.
Charlotte, North CarolinaAges 18–70 - NCT06884280RecruitingPhase 3
Comparing high and low dose iron for people on peritoneal dialysis
This trial tests whether a higher or lower dose of iron works better for people on peritoneal dialysis who have low iron levels. It aims to find the best way to treat iron deficiency in this group.
Hull, East Riding Of YorkshireAges 18 years+ - NCT06887829Recruiting
Radiation Therapy for Knee Osteoarthritis
This study tests a low-dose radiation treatment for knee osteoarthritis pain. If you have moderate arthritis pain and are a Mayo Clinic patient in Rochester, you may be able to join.
Rochester, MinnesotaAges 50–100 - NCT06889766RecruitingPhase 1
NY-ESO-1 T cells for advanced melanoma and sarcoma
This trial tests a personalized cell therapy using your own immune cells (T cells) that have been modified to recognize a protein called NY-ESO-1, which is found on some melanoma and sarcoma tumors. It may help people whose cancer has progressed after standard treatments.
Lausanne, Canton of VaudAges 18 years+
Common questions
- Are there clinical trials studying Low Dose?
- Yes. Clin2 currently lists 457 recruiting studies that include Low Dose, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Low Dose trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Low Dose an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Low Dose or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.