Treatment
Low Dose clinical trials
We’re tracking 457 recruiting studies that include Low Dose, each written for real people, not researchers, below.
Recruiting studies
- NCT06926595RecruitingPhase 2
Stem cell transplant with low-dose chemo for graft-versus-host disease prevention
This trial tests a stem cell transplant using a reduced-intensity chemotherapy regimen and a low dose of a drug called cyclophosphamide after the transplant to help prevent graft-versus-host disease (GVHD), a common complication where donor cells attack the recipient's body. It is for people with certain blood cancers or bone marrow disorders who have a suitable donor.
Hershey, PennsylvaniaAges 18 years+ - NCT06933134Recruiting
Using a biomarker to guide low-dose rituximab in rheumatoid arthritis
This trial aims to find out if a simple blood test (biomarker) can show whether a lower dose of rituximab will work for people with rheumatoid arthritis. If successful, it could help patients maintain good results with less medicine and fewer side effects.
ToursAges 18 years+ - NCT06933472RecruitingPhase 3
Study of a new phosphate binder for dialysis patients
This trial tests a new drug called AP301 to lower high phosphate levels in people on dialysis. It's designed to help control phosphate, which can be hard to manage with diet and current medications.
Granada Hills, CaliforniaAges 12 years+ - NCT06943859RecruitingPhase 2
Ketamine for opioid use disorder during methadone treatment
This study tests if a medicine called ketamine, given during methadone treatment, can help people reduce their use of opioids. It is for people who recently started methadone and have been using opioids heavily.
Baltimore, MarylandAges 18–65 - NCT06951802RecruitingPhase 4
Low-dose ketamine for pain during endometriosis surgery
This study tests whether giving a low dose of ketamine during endometriosis surgery can help reduce pain. If you qualify, you'll receive ketamine or a placebo during your procedure, and the team will check your pain levels afterward.
BernAges 18 years+ - NCT06956040Recruiting
Family doctor involvement in lung cancer screening
This study tests whether having your family doctor offer you a lung cancer screening scan (low-dose CT) can help find cancer early. You may qualify if you are a current or former heavy smoker and can travel to a Paris hospital for the scan.
ParisAges 50–74 - NCT06959537RecruitingPhase 1
Combination drug therapy for triple negative breast cancer
This trial tests a new combination of three drugs (cyclophosphamide, axatilimab, and retifanlimab) for people with metastatic triple negative breast cancer. The goal is to see if adding a low dose of chemotherapy can make the immunotherapy work better.
Houston, TexasAges 18 years+ - NCT06988943Recruiting
Finding lung cancer early with CT screening in Guangzhou communities
This study is testing a way to find lung cancer early by offering free CT scans to people in certain communities in Guangzhou. It helps catch cancer before symptoms start.
Guangzhou, GuangdongAges 40–74 - NCT07007364RecruitingPhase 2
Testing low-dose radiation with immunotherapy and chemo for early oral cancer
This trial tests if combining a low dose of radiation with an immunotherapy drug (adebrelimab) and a chemotherapy drug (albumin-bound paclitaxel) before surgery can help treat early-stage oral squamous cell carcinoma. It aims to see if this combination is safe and effective.
Wuhan, HubeiAges 18–70 - NCT07015151Recruiting
Mobile lung cancer screening for smokers and former smokers
This trial uses a mobile unit to screen people at high risk for lung cancer. It aims to catch the disease early, when it's easier to treat.
Pierre-BéniteAges 50–75 - NCT07050043RecruitingPhase 3
Low-dose nivolumab plus chemo vs standard chemo for advanced lung cancer
This trial tests whether a lower dose of the immunotherapy drug nivolumab combined with standard chemotherapy works better than chemotherapy alone for people with advanced or metastatic non-small cell lung cancer (NSCLC) that has not been treated before.
Alor Star, KedahAges 18 years+ - NCT07061574RecruitingPhase 1/Phase 2
Low-dose ATG with Adalimumab or Verapamil for new type 1 diabetes
This study tests if giving a low dose of an immune-suppressing drug (ATG) followed by either adalimumab or verapamil can help preserve insulin production in people recently diagnosed with type 1 diabetes. You may qualify if you are 9 to 20 years old, have had type 1 diabetes for less than 6 months, and have some natural insulin left.
San Francisco, CaliforniaAges 9–20 - NCT07062172Recruiting
Lung cancer screening for family members
This trial offers a low-dose chest CT scan to screen for lung cancer in family members of people with a specific genetic mutation driving their lung cancer. It aims to catch cancer early in those at higher risk.
Orange, CaliforniaAges 18–80 - NCT07085169RecruitingPhase 2
Low-dose chemo combo for advanced colorectal cancer
This trial tests a lower dose of a chemotherapy pill (trifluridine/tipiracil) combined with bevacizumab for advanced colorectal cancer that has not responded to at least two prior treatments. The goal is to see if this combination can help control the cancer with fewer side effects.
SanmingAges 60 years+ - NCT07089251RecruitingPhase 4
Epinephrine and tranexamic acid in knee replacement surgery
This study tests if using epinephrine and tranexamic acid together helps reduce bleeding and improve outcomes during knee replacement surgery. It may be a good fit if you are planning to have knee replacement and do not have certain medical conditions or allergies to these medicines.
Riyadh, Riyadh RegionAges 18–70 - NCT07099027Recruiting
Lung Health Check Pilot For Smokers Aged 55-74
This study is a lung health check pilot to find lung cancer early in people who are at higher risk because of their age and smoking history. You will get a free, low-dose CT scan to check for any signs of lung cancer.
DublinAges 55–74 - NCT07117045Recruiting
Low-dose CT scan for pancreatic cancer screening
This study uses artificial intelligence to analyze low-dose CT scans of the abdomen to detect early signs of pancreatic cancer. It may help find cancer before symptoms appear.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT07144527Recruiting
NMN supplement for exercise in healthy older adults
This trial tests whether a supplement called nicotinamide mononucleotide (NMN) can help healthy adults aged 60 to 80 improve their exercise tolerance. You'll take the supplement and do supervised cycling sessions to see if it boosts your stamina.
Beverly Hills, CaliforniaAges 60–80 - NCT07172204RecruitingPhase 2
Alternating chemo drugs for older or frailer adults with new AML
This trial tests a combination of two chemotherapy regimens given in turns for people with newly diagnosed acute myeloid leukemia (AML) who cannot have standard intensive chemotherapy. The goal is to find a gentler but effective treatment option.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07187193RecruitingPhase 2
Low-dose chemo plus thalidomide for untreated LCH
This trial tests a combination of two drugs, low-dose cytarabine and thalidomide, for adults with Langerhans cell histiocytosis (LCH) that has not been treated before with systemic therapy. The goal is to see if this treatment is safe and effective for people with LCH in multiple body areas or multiple spots in one system.
BeijingAges 18–70 - NCT07209345Recruiting
Scalp pain relief after brain surgery
This trial tests whether numbing the scalp before brain surgery can reduce pain afterward. You would receive a painkiller injection in your scalp before your surgery begins.
BeijingAges 18–64 - NCT07234487RecruitingPhase 2
Comparing two drug combos for advanced Hodgkin lymphoma
This trial tests a newer, lower-dose immunotherapy combination (AVD plus nivolumab) against a standard intensive chemo regimen (BEACOPP) that is adjusted based on PET scan results. It is for people with advanced classical Hodgkin lymphoma that has not been treated before.
MoscowAges 18–60 - NCT07239791Recruiting
Does a low-dose medication affect how we learn?
This study tests whether a very low dose of a medication called atomoxetine, which affects a brain chemical called noradrenaline, can help with how people learn. It is for right-handed adults who are generally healthy and not taking other medications.
ParisAges 18–39 - NCT06453876RecruitingPhase 3
Comparing clot removal, low-dose clot dissolver, and heparin for high-risk lung clot
This trial compares three treatments for an intermediate-high risk pulmonary embolism: a minimally invasive clot removal procedure (embolectomy), a low-dose clot-dissolving medication, or standard blood thinning (heparin). The goal is to see which approach works best to prevent worsening while reducing bleeding risks.
CopenhagenAges 18 years+
Common questions
- Are there clinical trials studying Low Dose?
- Yes. Clin2 currently lists 457 recruiting studies that include Low Dose, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Low Dose trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Low Dose an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Low Dose or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.