Treatment
Methylprednisolone clinical trials
We’re tracking 94 recruiting studies that include Methylprednisolone, each written for real people, not researchers, below.
Recruiting studies
- NCT07255248RecruitingPhase 4
Knee fat pad pain study for young female athletes
This study tests a treatment for knee fat pad pain in teenage girls who play organized sports. It aims to see if a specific injection helps after physical therapy hasn't worked.
Norwood, MassachusettsAges 12–18 - NCT05974462RecruitingPhase 3
Steroids for mild heart inflammation with weaker pumping
This trial tests whether a course of steroid medicine can improve outcomes in people with recently started myocarditis (heart muscle inflammation) and mildly reduced heart pumping. It compares steroids versus placebo (inactive treatment) to see if steroids help the heart recover and prevent worsening.
Edegem, AntwerpAges 18–69 - NCT07185633RecruitingPhase 2
Study of Gecacitinib and Steroids for Acute Graft-Versus-Host Disease
This study tests a new pill (gecacitinib) combined with steroids as the first treatment for moderate to severe acute graft-versus-host disease after a stem cell transplant. The goal is to see if this combination works better than steroids alone.
Suzhou, JiangsuAges 18 years+ - NCT06763848Recruiting
Blood filtering for NMOSD attacks
This trial tests a blood filtering procedure called Protein A immunoadsorption for people having an acute episode of neuromyelitis optica spectrum disorder (NMOSD). It may help remove harmful antibodies from your blood and reduce symptoms.
Guangzhou, GuangdongAges 18–65 - NCT07158476RecruitingPhase 4
Steroid injection for pain after ACL repair
This trial tests whether a single dose of methylprednisolone (a steroid) can reduce pain after ACL knee surgery. You will be randomly assigned to receive either the steroid or a placebo, and your pain levels will be tracked.
St Louis, MissouriAges 13–50 - NCT07077486RecruitingPhase 4
Testing telitacicept vs cyclophosphamide for lupus lung disease
This trial tests if a new drug called telitacicept works better than a standard lupus medicine (cyclophosphamide) to improve lupus-related lung scarring (interstitial lung disease). It might be an option if your breathing tests are still good enough.
Wuhan, HubeiAges 18–80 - NCT07081399RecruitingEarly Phase 1
Care plan to prevent complications after tube removal
This trial tests a special care plan for adults who are on a breathing machine (ventilator) for the first time. The goal is to see if this plan helps prevent problems after the breathing tube is removed.
Damanhūr, EgyptAges 18–60 - NCT07052929RecruitingPhase 1/Phase 2
Gene therapy study for young boys with XLMTM on ventilators
This study tests a new gene therapy called ASP2957 in young boys with X-linked myotubular myopathy who are dependent on a ventilator. The goal is to see if it can help improve their breathing and muscle strength.
Chicago, IllinoisAges Up to 3 years - NCT06968507RecruitingPhase 4
Steroid pills vs. ear injections for sudden hearing loss
This trial compares two treatments for sudden hearing loss: steroid pills taken by mouth or steroid injections into the ear. It aims to find which is more effective for patients who developed hearing loss within the last 2 weeks.
Istanbul, KartalAges 18–80 - NCT06936566RecruitingPhase 2
Ruxolitinib for graft-versus-host disease after transplant
This trial tests a drug called ruxolitinib for treating acute graft-versus-host disease (aGVHD), a common complication after a stem cell transplant. It may help control the immune reaction without using high doses of steroids.
Duarte, CaliforniaAges 18 years+ - NCT06922669Recruiting
Steroids for drug-induced liver injury with high bilirubin
This trial tests whether steroids (glucocorticoids) can help people with acute liver injury caused by a drug, especially when bilirubin levels are high. It aims to see if steroids can reduce liver damage and improve recovery.
Shenyang, LiaoningAges 18–80 - NCT06892210RecruitingPhase 4
Steroid comparison for COPD flare-ups
This trial compares two common steroids, hydrocortisone and prednisolone, to see which works better for treating COPD flare-ups. It may help you recover faster from a sudden worsening of your breathing.
Rønne, BornholmAges 40 years+ - NCT06892197RecruitingPhase 4
Comparing two steroids for severe pneumonia
This trial compares two common steroid medicines, hydrocortisone and prednisolone, to see which works better for people with severe community-acquired pneumonia. It aims to find the best treatment to help you recover faster.
Rønne, BornholmAges 18 years+ - NCT06841705RecruitingPhase 2
Early vedolizumab as first treatment for colitis from immunotherapy
This trial tests if giving vedolizumab early can help control severe diarrhea and colon inflammation caused by immunotherapy (a type of cancer treatment). It may offer a new option for people who develop these side effects.
Boston, MassachusettsAges 18 years+ - NCT06809998RecruitingPhase 1/Phase 2
Steroid injection in non-surgical knee before knee replacement
This study tests whether a single steroid injection in the healthy knee (the one not being replaced) can reduce pain and improve recovery after total knee replacement. It may help people who have arthritis in both knees but are only having one replaced now.
Toronto, OntarioAges 18 years+ - NCT05150704RecruitingPhase 3
Steroid treatment for suspected acute myocarditis in hospital
This study tests whether steroid medicine helps people hospitalized with suspected acute myocarditis (inflammation of the heart). Participants are randomly assigned to receive steroids or a placebo, and the trial looks at outcomes after the acute episode starts.
San Diego, CaliforniaAges 18–69 - NCT06676579RecruitingPhase 2
Avacopan for active IgA kidney disease with crescents
This trial tests if avacopan, a targeted anti-inflammatory drug, can safely treat a severe form of IgA nephropathy (IgAN) where small crescents form in the kidney filters. It may help reduce protein leakage and preserve kidney function.
Jacksonville, FloridaAges 18 years+ - NCT06670521RecruitingPhase 2
Steroids for swallowing problems after breathing tube removal
This trial tests a steroid medication (corticosteroids) to reduce swelling in the voice box after a breathing tube is taken out. It may help improve swallowing and reduce the risk of food or drink going into the lungs.
Aurora, ColoradoAges 18 years+ - NCT06474273RecruitingPhase 3
Treating acute rejection after a kidney or kidney-pancreas transplant
This study compares two ways of treating acute rejection (when the immune system attacks the new organ) in people who have had a kidney or combined kidney-pancreas transplant. It looks at whether adding a different approach helps protect the transplant long-term.
Lambton, New South WalesAges 2 years+ - NCT04936854RecruitingPhase 2
Sirolimus or steroid drops for active Graves eye disease
This Phase 2 study compares sirolimus versus corticosteroids to treat active thyroid eye disease. It aims to see which treatment works better to calm eye inflammation and improve symptoms, without needing urgent eye surgery.
Bergen, HordalandAges 18–80 - NCT06356571RecruitingPhase 2
Isatuximab with carfilzomib and dexamethasone for multiple myeloma
This trial tests a new combination of drugs (isatuximab, carfilzomib, and dexamethasone) given as shots under the skin for people whose multiple myeloma has come back or stopped responding to treatment. It aims to see if this mix works better than previous options.
Phoenix, ArizonaAges 18 years+ - NCT06317662RecruitingPhase 2
Adding venetoclax and blinatumomab to chemo for infant leukemia
This trial tests adding two newer medicines (venetoclax and blinatumomab) to standard chemotherapy for infants with a specific type of leukemia. The goal is to see if this combination helps more babies stay cancer-free.
Birmingham, AlabamaAges Up to 12 months - NCT06268704RecruitingPhase 4
Comparing two types of steroid injections for sacroiliac joint pain
This study compares two types of steroid medication used in injections for sacroiliac joint pain. It aims to see if one type works better than the other, helping patients with low back or buttocks pain find relief.
Albuquerque, New MexicoAges 18–99 - NCT02283996RecruitingPhase 4
Compare physical therapy for frozen shoulder
This study looks at how well physical therapy works for “frozen shoulder” and also compares the practical cost impact. It will randomly assign you to one of the study groups to see which approach helps most.
Boston, MassachusettsAges 18 years+
Common questions
- Are there clinical trials studying Methylprednisolone?
- Yes. Clin2 currently lists 94 recruiting studies that include Methylprednisolone, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Methylprednisolone trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Methylprednisolone an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Methylprednisolone or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.