Treatment
Tirzepatide clinical trials
We’re tracking 85 recruiting studies that include Tirzepatide, each written for real people, not researchers, below.
Recruiting studies
- NCT06582875RecruitingPhase 2
GLP-1 drug for polycystic kidney disease and weight
This study tests a GLP-1 receptor agonist (a type of medicine that helps with weight and metabolism) in people with polycystic kidney disease who are overweight. It aims to see if this drug can help slow kidney disease progression.
Aurora, ColoradoAges 18–65 - NCT07094568Recruiting
Comparing tirzepatide and liraglutide for bone health in severe obesity
This study compares two medicines, tirzepatide and liraglutide, to see how they affect bone health in people with severe obesity. If you have a high BMI and no major health problems, this trial could help doctors understand which treatment is better for your bones.
Athens, AtticaAges 30–65 - NCT07095517RecruitingPhase 1
Preventing early-onset colorectal tumors with tirzepatide
This study tests if tirzepatide can help prevent early-onset colorectal tumors in people aged 18-50 who have had certain types of polyps removed. It aims to find risk factors and ways to stop colorectal cancer before it starts.
Boston, MassachusettsAges 18–50 - NCT07057310Enrolling by invitationPhase 4
Weight Loss Drug for Postmenopausal Women With Obesity
This study tests a GLP-1 agonist medication (like Ozempic) to help postmenopausal women lose weight and improve physical and blood vessel health. It focuses on women aged 46–60 with obesity.
Jacksonville, FloridaAges 46–60 - NCT06976853RecruitingPhase 2
Testing a new drug for Crohn’s disease beyond inflammation
This study tests a medicine called tirzepatide to see if it can help people with active Crohn’s disease who have not responded to multiple prior treatments. It focuses on how the drug might work beyond just reducing inflammation.
Beverly Hills, CaliforniaAges 18–80 - NCT06897475RecruitingPhase 2
Study of LY3457263 for type 2 diabetes on semaglutide or tirzepatide
This study tests if adding LY3457263 helps lower blood sugar in people with type 2 diabetes who are already taking a stable dose of semaglutide or tirzepatide. You will be randomly assigned to get either LY3457263 or a placebo.
Phoenix, ArizonaAges 18–75 - NCT06774079RecruitingPhase 4
GLP-1 drug and diet study for Crohn's disease patients
This study tests a drug that helps with weight loss and blood sugar (called a GLP-1 receptor agonist) combined with a special diet to see if it can improve symptoms in people with mild Crohn's disease. You may join if you have Crohn's, a BMI of 27 or higher, and are already on a stable dose of a TNF blocker.
Miami, FloridaAges 18 years+ - NCT06751589RecruitingEarly Phase 1
Weight loss drug study for people with endometrial cancer
This study tests if adding a weight loss medication (tirzepatide or semaglutide) during chemotherapy helps people with early-stage endometrial cancer who are overweight or have diabetes. It aims to see if weight loss can improve treatment outcomes.
Basking Ridge, New JerseyAges 18 years+ - NCT06700538RecruitingPhase 1/Phase 2
Study of an experimental drug for obesity with or without type 2 diabetes
This study tests an experimental medication called ARO-INHBE in adults with obesity, including those who also have type 2 diabetes. The goal is to see if it helps with weight loss and is safe.
CamberwellAges 18–65 - NCT06630585RecruitingPhase 3
Tirzepatide added to insulin pump for type 1 diabetes
This study tests whether adding a weekly injection of tirzepatide (a drug that helps with blood sugar and weight) can improve glucose control in adults with type 1 diabetes who already use an automated insulin pump. It may help you if your blood sugar is not at target despite using a pump.
Chêne-Bougeries, Canton of GenevaAges 18–65 - NCT06575738RecruitingPhase 1
Semaglutide for teens after weight-loss surgery
This study looks at how teenagers and young adults respond to weight-loss surgery (sleeve gastrectomy) and whether adding a medication called semaglutide can help improve weight loss. It has two parts: first observing how surgery affects you, then testing if semaglutide helps those who didn't lose enough weight after surgery.
Aurora, ColoradoAges 12–24 - NCT06246799RecruitingPhase 3
Comparing two pill combinations for new diabetes
This study compares two different two-drug combinations for people recently diagnosed with type 2 diabetes. It aims to find which combination works better to control blood sugar and improve overall health.
San Antonio, TexasAges 18–75 - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Chandler, ArizonaAges 18–75
Common questions
- Are there clinical trials studying Tirzepatide?
- Yes. Clin2 currently lists 85 recruiting studies that include Tirzepatide, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Tirzepatide trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Tirzepatide an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Tirzepatide or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.