Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 458 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07367100Recruiting
Testing a new clot-removal catheter for stroke
This study tests a special catheter (a thin tube) designed to remove blood clots from large arteries in the brain during a stroke. The goal is to see if it is safe and effective at restoring blood flow.
EdegemAges 18–90 - NCT07379190RecruitingPhase 3
Tirofiban for late window stroke due to artery plaque
This trial tests whether a drug called tirofiban can help people who had a stroke more than 24 hours ago but within 7 days. It is for strokes caused by a buildup of plaque in a large brain artery, and uses a special MRI to confirm the cause.
Weifang, China/Shandong ProvinceAges 18 years+ - NCT07396337RecruitingPhase 2
Study of QHRD106 injection for acute ischemic stroke
This trial tests an investigational drug, QHRD106, given as an injection for people who have had a moderate-to-severe acute ischemic stroke. It aims to see if the drug can help recovery when given within 24 hours after the stroke starts, and it is for patients who are not receiving standard clot-busting treatment.
Nanjing, JiangsuAges 18–80 - NCT02879123Recruiting
Recovery after stroke treatment with a clot-removal procedure
This trial studies how the brain and nervous system recover about 3 months after a clot-removal treatment for an acute ischemic stroke. It may help doctors better understand what recovery looks like after this kind of stroke care.
ParisAges Any age - NCT03356392Recruiting
Registry for stroke patients getting clot-busting treatment
This study records information from adults with an acute ischemic stroke (a stroke caused by a blocked artery) who receive clot-busting medicine within 4.5 hours. It may help doctors better understand which patients benefit from treatment and how care decisions are made for certain blocked brain arteries.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07550296RecruitingPhase 2
Second IV Clot-Dissolving Treatment for Major Stroke
This trial tests giving a second dose of an IV clot-dissolving medicine (prourokinase) to patients who had a stroke from a large clot but didn't improve enough after the first dose. The goal is to see if a second dose within 6 hours of stroke onset can help more patients recover.
Shenyang, None SelectedAges 18–80 - NCT07404852Recruiting
Vagus nerve stimulation for reducing inflammation after stroke
This trial tests whether a non-invasive device that stimulates the vagus nerve can reduce inflammation and brain injury after a stroke caused by a large blood clot.
St Louis, MissouriAges 18–99 - NCT07406971RecruitingPhase 2
Capsaicin nose spray for acute stroke
This trial tests a capsaicin spray applied inside the nose to stimulate a nerve cluster behind the nose, which may help improve blood flow in people having a moderate to severe stroke within the last 24 hours.
Aguascalientes, AguascalientesAges 18 years+ - NCT07419997Recruiting
Observational study on clot-busting drugs beyond the usual window
This study looks at patients who received a clot-busting drug (intravenous thrombolysis) for their stroke 4.5 to 24 hours after symptoms started. It aims to see how well this works and what happens to them, using data that has already been collected.
BeijingAges 18 years+ - NCT07436156RecruitingPhase 4
Stroke treatment study using a new clot removal system
This study looks at people who had an ischemic stroke and were treated with a special clot-removal device. It aims to learn how well this treatment works in real-world patients.
West Jordan, UtahAges 18 years+ - NCT07674329Recruiting
Virtual reality rehab for arm strength after stroke
This trial tests if using virtual reality (VR) exercises early after an ischemic stroke can help improve arm muscle strength, thinking skills, and mood. It is for people who have had a stroke within the last 10 days.
TaipeiAges 18–85 - NCT07519044RecruitingPhase 4
GM1 drug added to clot removal for acute stroke
This study tests whether adding a medicine called GM1 to emergency clot-removal surgery helps people recover better from sudden strokes caused by blood clots in major brain arteries. GM1 may protect brain cells from damage during and after the stroke.
Beijing, Beijing MunicipalityAges 18–80 - NCT07540741Recruiting
PCSK9 Inhibitors for Large-Artery Stroke Recovery
This trial tests whether a cholesterol-lowering medication called evolocumab (a PCSK9 inhibitor) can help people recover better after a specific type of stroke caused by clogged arteries. The study checks if lowering cholesterol further than usual statins do improves stroke outcomes and is safe.
HeilongjiangAges 18–80 - NCT07556068Recruiting
Brain Blood Flow Recovery After Stroke Clot Removal
This study enrolls people who had an acute ischemic stroke (caused by a blood clot) and received emergency treatment to remove the clot. Researchers want to understand why some patients recover well while others don't, by measuring how the brain regulates its own blood flow after treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07575984RecruitingPhase 4
Mexidol Safety and Efficacy for Acute Ischemic Stroke
This trial tests whether Mexidol, a medication that may protect brain tissue, can help people recover better after an acute ischemic stroke (a type of stroke caused by a blood clot). The study includes stroke patients and healthy volunteers to understand how the drug works and if it's safe.
ArkhangelskAges 18–90 - NCT07581210RecruitingPhase 2
QD202 Study for Recent Stroke Treated With Clot-Busting Medicine
This study tests whether a new drug called QD202 can help protect the brain and improve recovery when given alongside standard clot-busting therapy (thrombolysis) for acute ischemic stroke. You would be in the trial if you had a stroke in the last 24 hours and are receiving or planning to receive thrombolytic treatment.
Meizhou, GuangdongAges 18–85 - NCT07606807RecruitingPhase 3
New clot-busting medication for stroke in the extended time window
This trial tests a new medication called rhTNK-tPA for treating acute ischemic stroke (a clot in the brain) up to 24 hours after symptom onset. The study uses simplified imaging to determine eligibility and aims to help patients recover better outcomes.
GuangzhouAges 18 years+ - NCT07627399Recruiting
Best Care Practices for Stroke in Regular Hospital Units
This study tests whether following best-practice guidelines for stroke care in regular hospital units (rather than specialized stroke centers) helps patients recover better. Researchers will track how well patients do when they receive standardized stroke care protocols.
Antequera, MálagaAges 18 years+ - NCT07491744Enrolling by invitation
Stroke and TIA study on heart and blood vessel health
This study looks at the causes of stroke and TIA by doing extra tests on patients admitted to the hospital. It aims to better understand and prevent future heart and blood vessel problems.
Stockholm, Stockholm CountyAges 18 years+ - NCT06961487Enrolling by invitation
Stroke treatment trial for large area brain damage
This trial tests if a procedure to remove a large blood clot from the brain (called a thrombectomy) can help people with severe strokes who have a large damaged area. It is for people who can be treated within 24 hours of their stroke starting.
Palo Alto, CaliforniaAges 18–90 - NCT06781385Enrolling by invitationPhase 2
Tenecteplase after clot removal for severe stroke
This trial tests if giving a clot-busting drug (tenecteplase) directly into the brain artery after a successful clot-removal procedure can improve outcomes for people with a major stroke. It is for patients who had a large vessel blockage and received endovascular thrombectomy within 24 hours of symptoms starting.
Charlotte, North CarolinaAges 18 years+ - NCT06755944Enrolling by invitationPhase 2/Phase 3
Study of XY03-EA tablets for recent stroke recovery
This trial tests whether XY03-EA tablets can help people recover after an acute ischemic stroke. Participants must have had a stroke within the last 48 hours and have moderate to severe symptoms but not be in a coma.
Shijiazhuang, HebeiAges 18–80 - NCT05967728Enrolling by invitationPhase 2
Testing remote arm conditioning to protect the brain in stroke
This Phase 2 study tests whether a simple remote method that briefly reduces blood flow in the arm (called ischemic conditioning) can help people with brain small-vessel disease or an acute ischemic stroke. Participants are monitored by phone and, for stroke patients, through a Mobile Stroke Unit.
Calgary, AlbertaAges 55 years+ - NCT06924996Enrolling by invitation
Thrombectomy for large stroke in back of the brain
This trial is testing whether a clot removal procedure, called endovascular thrombectomy, can help people who have a large stroke in the back part of the brain. To be eligible, the stroke must be from a blocked artery in the base of the skull, and the stroke must be severe and recent.
Beijing, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 458 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.