Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 447 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07083986Enrolling by invitation
Surgery vs stenting for recent stroke patients
This trial compares two procedures to open a blocked carotid artery in people who recently had a stroke. One option is surgery (carotid endarterectomy) to remove the blockage, the other is stenting (placing a small mesh tube to hold the artery open). The goal is to see which works better for patients still having some stroke symptoms.
MoscowAges 18 years+ - NCT06924996Enrolling by invitation
Thrombectomy for large stroke in back of the brain
This trial is testing whether a clot removal procedure, called endovascular thrombectomy, can help people who have a large stroke in the back part of the brain. To be eligible, the stroke must be from a blocked artery in the base of the skull, and the stroke must be severe and recent.
Beijing, Beijing MunicipalityAges 18–80 - NCT05242393Recruiting
How daily body rhythms relate to recovery after stroke
This observational study looks at how your body’s daily rhythms may affect brain recovery after an ischemic stroke. It may help researchers understand what timing-related factors influence “neuroplasticity,” meaning the brain’s ability to adjust and heal.
Saint PetersburgAges 18–80 - NCT03571763Recruiting
Anti-clotting treatment study in stroke patients with small brain bleeds
This trial looks at how anti-clotting medicines affect small blood vessel bleeds in the brain (cerebral microbleeds) and larger bleeding in the skull after an ischemic stroke. It may help doctors choose safer prevention medicines for people who already have these small bleeds seen on brain MRI.
ShenyangAges 18 years+ - NCT06665386Recruiting
Cooling infusion with clot removal for severe stroke
This study tests whether cooling the brain during clot removal (thrombectomy) can improve recovery after a severe stroke caused by a large blood vessel blockage. Researchers will use blood tests to find markers that may predict who benefits most.
Dalian, LiaoningAges 18–80 - NCT06100718Recruiting
Detecting new cancer after a stroke in at-risk patients
This study looks for hidden cancers in people who have had a stroke and have high levels of a blood marker called D-dimer. It aims to see if a full cancer screening one year later can find new cancers that might have been missed.
Lausanne, Canton of VaudAges 18 years+ - NCT07237542Recruiting
Remote ischemic preconditioning for small stroke prevention
This study tests whether a simple, non-invasive treatment called remote ischemic preconditioning (using brief periods of blood pressure cuff inflation on the arm) can help prevent early neurological worsening in people who have had a small, specific type of stroke. It may offer a safe way to protect your brain while you recover.
Nanjing, JiangsuAges 18 years+ - NCT06963489Recruiting
Stroke biobank study for large vessel blockage
This study collects blood and tissue samples from people who had a stroke caused by a blockage in a large artery in the brain. The goal is to learn more about the condition by studying these samples over time.
Wuhu, AnhuiAges Any age - NCT05871606RecruitingPhase 1
Breathing nitric oxide during clot-removal for stroke
This Phase 1 study tests whether inhaled nitric oxide (a gas breathed through a ventilator) can improve outcomes in people having a specific kind of emergency stroke procedure to remove a clot from the brain. It focuses on patients who need general anesthesia for the clot-removal procedure and have imaging results that suggest salvageable brain tissue.
Charlotte, North CarolinaAges 18–80 - NCT06319846RecruitingPhase 3
Tirofiban for recent mild stroke or TIA with narrowed brain artery
This trial tests the drug tirofiban (a blood thinner) to prevent another stroke in people who have had a mild stroke or high-risk TIA and have a narrowed artery in the brain. It must be started within 24 hours of symptoms.
Harbin, HeilongjiangAges 40 years+ - NCT06005233Recruiting
Smartwatch heart monitoring after unexplained stroke
This trial uses a smartwatch to look for hidden atrial fibrillation (an irregular heart rhythm) in people who have had a stroke or TIA with no known cause. It could help find the reason for the stroke and guide treatment to prevent another one.
MunichAges 40 years+ - NCT07552610Recruiting
Sivelestat sodium added to clot removal surgery for stroke
This trial tests whether adding a medication called sivelestat sodium to emergency clot removal surgery (mechanical thrombectomy) can improve outcomes in patients with a specific type of stroke caused by a large blood clot in the front part of the brain. The goal is to see if this combination treatment leads to better recovery.
Weifang, ShandongAges 18–80 - NCT06342206Recruiting
TCM Assessment for Recent Ischemic Stroke
This study uses traditional Chinese medicine (TCM) diagnostic tools to evaluate patients who had an ischemic stroke within the last 10 days. It aims to understand the acute and chronic phases of stroke to help guide future treatments.
ChanghuaAges 20 years+ - NCT06987305RecruitingPhase 3
Clot-busting medication before clot removal for late-arriving stroke
This trial tests whether adding a clot-busting medication (rhTNK-tPA) before a clot-removal procedure (thrombectomy) can improve outcomes for people who have a moderate-to-severe stroke and arrive at the hospital 4.5 to 24 hours after symptoms start. It's for those with a large artery blockage but still enough brain tissue that can be saved.
Wuhan, HubeiAges 18 years+ - NCT03481205Recruiting
Air-transport treatment to protect brain tissue after stroke
This trial studies a protective “conditioning” treatment given during air ambulance transport for people with a suspected large-vessel ischemic stroke. The goal is to reduce further brain injury and preserve more brain tissue while you’re being transported for stroke care.
Iowa City, IowaAges 18–80 - NCT07044830Recruiting
Sleep apnea treatment for stroke recovery
This trial tests whether treating sleep apnea with a CPAP machine soon after a stroke can improve recovery. It is for people who had their first moderate-to-severe ischemic stroke and have not used CPAP before.
Ribeirão Preto, São PauloAges 18–80 - NCT05697575Recruiting
Staphylokinase during stroke blood-flow treatment
This trial studies using a medication called non-immunogenic staphylokinase as part of standard clot-busting treatment for an acute ischemic stroke. It may help clinicians improve blood flow after the stroke using an approach designed to be less likely to trigger immune reactions.
Saint PetersburgAges 18–85 - NCT07420374Recruiting
Outpatient stroke care for older patients
This study tests whether older people with minor strokes or warning signs can be safely treated at home or in an outpatient clinic instead of staying in the hospital. It may be a good fit if you recently had a mild stroke and do not need complex medical care.
HeidelbergAges 60 years+ - NCT04942041Recruiting
Thrombectomy for large stroke blockages at low-volume centers
This study tests whether using a procedure called mechanical thrombectomy at smaller stroke centers can improve outcomes after a large-vessel stroke. It may help people who have a major artery blockage get timely treatment, with measured effects on complications and survival.
Kristiansand, AgderAges 18–100 - NCT07253181RecruitingPhase 3
Stroke clot-busting drug before transfer for artery clearing
This trial tests whether giving a clot-busting drug (tenecteplase) before transferring you to a hospital that can do a procedure to remove the clot improves outcomes for people who had a stroke up to 24 hours earlier. You may qualify if you have a blockage in a large artery in the front of your brain and can still get the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06352619Recruiting
Lowering blood pressure after clot removal for stroke
This trial tests whether lowering blood pressure soon after a clot-removal procedure for stroke can improve recovery. It is for people whose blood pressure remains high after the procedure.
Sydney, New South WalesAges 18 years+ - NCT07002476RecruitingPhase 3
Early aggressive cholesterol-lowering after stroke with clot removal
This trial tests whether quickly starting an aggressive cholesterol-lowering treatment after a stroke improves recovery. It is for people who are about to have a procedure to remove a large blood clot from their brain.
ShanghaiAges 18 years+ - NCT04839887Recruiting
Quality of life after stroke in adults aged 18–65
This trial looks at what affects quality of life after an ischemic stroke (a type of stroke caused by a blocked blood vessel) in younger adults. You may be able to join if you can complete questionnaires about your recovery and daily life.
OlomoucAges 18–65 - NCT07594314RecruitingPhase 2/Phase 3
Minocycline after stroke clot removal surgery
This trial tests whether minocycline, an antibiotic, can reduce brain damage when given after successful clot removal surgery for acute stroke. The goal is to see if this medication helps patients recover better.
Wuhan, HubeiAges 18 years+
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Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 447 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.