Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 447 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06210633Recruiting
Clot removal trial for very large strokes
This trial tests a procedure called endovascular thrombectomy (clot removal through a catheter) for people with very large strokes. It aims to see if removing the clot can help even when a large part of the brain is already damaged.
Xiangtan, HunanAges 18 years+ - NCT06226805RecruitingPhase 2
Study of BB-031 for acute ischemic stroke
This trial tests a new drug called BB-031 for people who have had a stroke caused by a blocked blood vessel in the brain. The drug may help restore blood flow and reduce damage if given within 24 hours of symptoms starting.
Scottsdale, ArizonaAges 18 years+ - NCT06175715Recruiting
General vs. local anesthesia for carotid artery surgery after stroke
This trial compares two types of anesthesia for people who need surgery to clean out a blocked carotid artery after a recent stroke. It aims to see which anesthesia method leads to better recovery after the surgery.
MoscowAges 40–80 - NCT06143488Recruiting
Clot removal versus medication for mild stroke with large vessel blockage
This trial compares a procedure to remove the blockage (endovascular therapy) with the best medications alone for people who have a mild stroke caused by a large blocked artery in the brain. The goal is to see if the procedure can improve recovery better than medicine alone.
Wuhu, AnhuiAges 18 years+ - NCT06155032Recruiting
Clot Removal for Worsening Mild Stroke
This trial tests whether emergency clot removal (endovascular therapy) can help people whose mild stroke gets worse within a week. It's for those who have a blockage in a large brain artery and enough healthy brain tissue to save.
Fuyang, AnhuiAges 18 years+ - NCT06129175RecruitingPhase 2/Phase 3
Stem cells for recent moderate to severe stroke
This trial is testing a new treatment using stem cells from donated umbilical cord tissue to help people recover from a recent moderate to severe stroke. It is for patients who cannot receive standard clot-busting treatments.
Cheras, Kuala LumpurAges 18 years+ - NCT06121336Recruiting
Tracking a blood marker to measure stroke recovery
This study is looking at a protein in the blood called brain-derived tau, which may increase after a stroke. By measuring it over time, doctors hope to learn more about how the brain is healing and possibly predict recovery.
Munich, BavariaAges 18 years+ - NCT06094478Recruiting
Stroke emergency protocol study
This study tests a hospital stroke protocol to quickly evaluate and manage patients with a stroke caused by a clot (AIS), bleeding in the brain (ICH), or bleeding around the brain (SAH). It may help improve emergency care and outcomes.
New Haven, ConnecticutAges 18 years+ - NCT06045156Recruiting
Tirofiban after clot-busting for stroke
This trial tests whether giving tirofiban (a blood thinner) shortly after the standard clot-busting drug tenecteplase can improve recovery from a moderate stroke. It is for people who have had a stroke within the last few hours and do not have certain risk factors like irregular heart rhythm or recent bleeding.
Changchun, JilinAges 18 years+ - NCT06010628RecruitingPhase 4
Tenecteplase for stroke 4.5 to 6 hours after onset
This trial tests a medicine called tenecteplase (a clot-buster) for people who have a moderate or severe stroke caused by a clot and can be treated 4.5 to 6 hours after symptoms start. It aims to see if this medicine can help improve recovery.
Shenyang, None SelectedAges 18 years+ - NCT06010641Recruiting
Head-down position for stroke from large artery blockage
This trial tests if lying with the head lower than the body (head-down position) can help people who are having a stroke caused by a blockage in a large artery in the front part of the brain. The goal is to see if this simple position improves blood flow and reduces disability.
ShenyangAges 18 years+ - NCT05967728Enrolling by invitationPhase 2
Testing remote arm conditioning to protect the brain in stroke
This Phase 2 study tests whether a simple remote method that briefly reduces blood flow in the arm (called ischemic conditioning) can help people with brain small-vessel disease or an acute ischemic stroke. Participants are monitored by phone and, for stroke patients, through a Mobile Stroke Unit.
Calgary, AlbertaAges 55 years+ - NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Birmingham, AlabamaAges 18 years+ - NCT05903560Recruiting
Arm versus leg access for clot removal in basilar stroke
This trial compares doing a clot-removal procedure through the arm artery versus the leg artery for an emergency stroke caused by a blocked basilar artery. It aims to see which access route is safer and more effective for restoring blood flow when time is critical.
Nanjing, JiangsuAges 18 years+ - NCT05892510RecruitingPhase 2/Phase 3
Tenecteplase after clot removal for no-reflow stroke
This trial tests whether giving tenecteplase directly into the brain artery after a thrombectomy can improve outcomes when blood flow doesn’t fully return (“no-reflow”) in an emergency stroke. It may help some people by reducing ongoing clot-related blockage after the main clot is removed.
Gold Coast, QueenslandAges 18 years+ - NCT05847699Recruiting
MRI study of stroke brain changes after decompression surgery
This study looks at how MRI findings match what doctors see in brain tissue after treatment for a type of severe stroke. It may help researchers better understand which brain changes happen early and how decompressive surgery affects them.
ParisAges 18 years+ - NCT05363397RecruitingPhase 2
Adjunctive TBO-309 added to stroke clot removal treatment safety
This Phase 2 trial studies whether adding TBO-309 to standard emergency treatment for acute ischemic stroke is safe and tolerable. It may help researchers see if the added drug can be given without causing excessive side effects alongside clot-busting and/or clot-removal procedures.
Camperdown, New South WalesAges 18 years+ - NCT05756257Recruiting
MRI study of blood pressure swings after ischemic stroke
This trial looks at whether changes in blood pressure after an ischemic stroke (a stroke caused by blocked blood flow) are linked to recovery and outcomes. You may be asked to have MRI scans soon after arriving to help researchers understand who is at higher risk and why.
New Haven, ConnecticutAges 18 years+ - NCT05760846Recruiting
Training hand skills after a recent stroke
This study looks at a therapy that helps people with a recent stroke relearn coordinated hand and arm movements. It compares how well motor skill learning works and may help improve functional use of the affected arm.
Yvoir, NamurAges 18–90 - NCT05686642RecruitingPhase 2
Drug LT3001 for sudden stroke symptoms within 24 hours
This Phase 2 study tests LT3001 to improve recovery after an acute ischemic stroke (a stroke caused by blocked blood flow). It is designed for people who can be treated within 24 hours of symptom onset and who meet specific safety and health requirements.
Beijing, Beijing MunicipalityAges 18–80 - NCT05691244RecruitingPhase 3
Tested drug for acute ischemic stroke within 24 hours
This Phase 3 trial studies sovateltide (and a placebo) in adults with an ischemic stroke, aiming to improve safety and outcomes. It focuses on people who can start treatment quickly after stroke symptoms begin and who do not have bleeding in the brain on imaging.
Tucson, ArizonaAges 18–80 - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Mobile, AlabamaAges 18–79 - NCT05600374Recruiting
Brain stimulation timed to brain rhythms after recent stroke
This trial tests a special brain-stimulation approach that targets your brain’s natural 8–12 Hz rhythm to improve arm and hand recovery after stroke. It’s designed for people in the early days after an ischemic stroke, when motor recovery is still changing quickly.
Frankfurt a.M., Frankfurt a.M.Ages 18 years+ - NCT05604638RecruitingPhase 3
Tirofiban soon after tenecteplase for acute stroke flare
This trial tests whether starting tirofiban soon after tenecteplase can improve outcomes for people whose stroke symptoms temporarily get worse after treatment. It aims to see if the added medicine can reduce harmful clot-related changes after initial thrombolysis.
Chuzhou, AnhuiAges 18 years+
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Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 447 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.