Clinical trials
Acute Pain clinical trials
Below are recruiting acute pain clinical trials, each written for real people, not researchers. We’re tracking 202 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07604376Recruiting
Nerve Block Pain Relief After Cesarean Delivery
This study tests whether a nerve-numbing injection in the abdomen helps reduce pain after a cesarean (C-section) delivery. The injection uses a local anesthetic to numb the area around your surgical wound, potentially reducing pain and the need for stronger pain medicines after surgery.
Târgu Mureş, Mureș CountyAges 18 years+ - NCT06386224Recruiting
Online pain self-management for pancreatitis pain
This study tests an online pain-management program for adults with chronic or recurrent acute pancreatitis. The program is done on your own device (or a loaner iPad) and is designed to help you learn skills to cope with pain and improve daily life.
Seattle, WashingtonAges 18 years+ - NCT05172739RecruitingPhase 4
Opioid-free anesthesia during lung surgery for early lung cancer
This study tests whether an opioid-free pain/anesthesia plan during elective lung surgery can reduce surgical “stress” on the body and affect the immune system. You may be eligible if you have early-stage non-small cell lung cancer and are scheduled for a specific type of surgery (VATS lobectomy).
Heraklion, CreteAges 18–80 - NCT07394673Recruiting
Nerve block for pain after shoulder surgery
This trial tests a new ultrasound-guided nerve block for pain relief after shoulder surgery. It aims to improve comfort and reduce the need for pain medications.
BursaAges 18–65 - NCT06369922Recruiting
TENS for pain during urethral bulking for incontinence
This trial tests whether using a TENS device (a mild electrical stimulation machine) during an in-office urethral bulking procedure helps reduce pain. If you are a woman with stress urinary incontinence scheduled for this treatment, you may be able to join.
Rochester, New YorkAges 18 years+ - NCT06222151Recruiting
Recovering from weight-loss surgery with early walking
This study tests whether starting a supervised walking program soon after weight-loss surgery helps you recover faster. It aims to see if early movement improves your recovery and hospital stay.
Esbjerg, Region SyddanmarkAges 18–70 - NCT06655337Recruiting
Testing a smartphone app for managing hospital discharge
This study tests whether a smartphone app called Medidux helps you manage your symptoms and discharge from the hospital if you came in with coughing, back pain, or belly discomfort. You'll use the app to report how you're feeling, and the care team can check in with you after you leave.
Horgen, Canton of ZurichAges 18 years+ - NCT07446868Recruiting
Comparing two nerve blocks for pain after mastectomy
This trial compares two nerve-block techniques (SPSIP and ESPB) to see which one provides better pain relief after breast cancer surgery. The goal is to reduce pain and improve recovery after a modified radical mastectomy.
Cairo, Cairo GovernorateAges 18–65 - NCT05767619Recruiting
Digital tool to guide care for chest pain calls
This trial tests a digital decision-support tool that helps emergency teams manage people who call for help because of chest pain. It may improve how safely and consistently chest pain is assessed and treated in the ambulance setting.
Kungsbacka, Region HallandAges 18 years+ - NCT07745972Recruiting
Pain relief block for gallbladder surgery
This trial tests a numbing injection near the ribs to reduce pain after laparoscopic gallbladder removal. It may help you recover with less discomfort.
IstanbulAges 18–80 - NCT07192965Recruiting
Heart scan without ECG for chest pain with high troponin
This trial tests if a coronary CT scan (without needing an ECG) can safely guide care for people who come to the emergency room with chest pain and a high troponin level. It aims to see if this approach works as well as standard tests.
JetteAges 30 years+ - NCT06795126Enrolling by invitation
Virtual reality for pain and anxiety in kids getting IVs
This study tests if a virtual reality game called Little NIRVANA can help reduce pain and anxiety in children getting an IV. It's for kids ages 2 to 8 in the emergency department.
Columbus, OhioAges 2–8 - NCT06020677Recruiting
Study on Latinx children's pain after surgery
This study looks at how parents manage their child's pain after surgery, focusing on Latinx families who speak Spanish at home. By understanding these experiences, doctors hope to improve pain care for children.
Orange, CaliforniaAges 2–12 - NCT05673551Enrolling by invitation
VR during at-home burn dressing changes for kids
This trial tests whether virtual reality (VR) can help children feel better during daily burn dressing changes at home. It will study comfort and pain around the first time you do dressings after leaving the hospital.
Columbus, OhioAges 6–17 - NCT07434427RecruitingPhase 4
Buprenorphine vs. oxycodone for pain after lung surgery
This study compares two common pain medicines given through a patient-controlled pump after lung surgery done with small incisions. The goal is to see which one works better and has fewer side effects.
Zabrze, Silesian VoivodeshipAges 18–75 - NCT07665762RecruitingPhase 3
Numbing medicine for arm surgery pain prevention
This trial compares two additives to standard numbing medicine given before wrist fracture surgery to see which better prevents severe pain. You may qualify if you have risk factors for hard-to-control pain after surgery.
Hong KongAges 18–90 - NCT07452120Recruiting
Comparing two nerve blocks for pain after hip surgery
This trial studies two different nerve block methods to see which provides better pain relief after hip replacement surgery. If you are having hip surgery and want to help find the best way to manage pain, this study may be for you.
Sivas, SivasAges 18 years+ - NCT07739277Recruiting
Comparing two ways to give a chest wall pain block for breast surgery
This study compares two ways of giving a numbing injection (a nerve block) to the side of the chest wall for pain relief after breast surgery. The goal is to see which method works better for reducing pain and the need for pain medicine.
Ankara, Yenimahalle\AnkaraAges 18–65 - NCT06838572Recruiting
Cooling the wrist to reduce pain from arterial line placement
This study tests whether cooling the skin on your wrist before a routine arterial line placement (a small tube in your wrist artery) can reduce the pain of the procedure. If you are having surgery and need an arterial line, this might help make the experience more comfortable.
Chongqing, Chongqing MunicipalityAges Any age - NCT07023497Recruiting
Finding the best dose of spinal morphine for C-section pain relief
This study tests different doses of morphine given through a spinal injection during a planned C-section to find the best balance of pain relief and side effects. It may help women have better pain control after surgery.
Ioannina, EpirusAges 18–50 - NCT06379425RecruitingPhase 4
Can pain meds without opioids help you pee sooner after surgery?
This study looks at whether giving a mix of pain medicines (without opioids) before surgery can help you recover faster and avoid needing a catheter after a vaginal repair or sling procedure. It enrolls women having minor gynecologic surgery at the South Shore Surgery Center in New York.
Bay Shore, New YorkAges Any age - NCT07486505Recruiting
Mindfulness for pain after arm or leg fracture surgery
This study tests whether brief mindfulness sessions before and after surgery help people manage pain and anxiety while recovering from a broken arm or leg, and may reduce the need for strong painkillers (opioids). It aims to see if this approach is practical and helpful for patients.
Hamilton, OntarioAges 18 years+ - NCT07161323Recruiting
Trial of two exercises for leg pain from sciatica
This trial compares two simple exercises (SNAG and SNME) to see which works better for people with long-lasting sciatic leg pain. If you have had pain going down one leg for over 3 months and have not had treatment in the last month, this study may help find relief.
IstanbulAges 20–50 - NCT06395428RecruitingPhase 4
Haloperidol for severe back pain in the ER
This study tests whether the medication haloperidol, given in the emergency room, can help relieve severe back pain that started on its own (not from an injury). It compares haloperidol to a common pain reliever called ketorolac.
Kalamazoo, MichiganAges 18–65
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Common questions
- Are there clinical trials for acute pain?
- Yes. Clin2 currently lists 202 recruiting acute pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.