Clinical trials
Advanced clinical trials
Below are recruiting advanced clinical trials, each written for real people, not researchers. We’re tracking 3,977 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07126158RecruitingPhase 2
Radiation plus targeted drugs for advanced pancreatic cancer
This trial tests a combination of targeted radiation and two oral drugs (defactinib and avutometinib) for people with advanced pancreatic cancer that hasn't spread to distant organs. It may be an option if you've already had at least 2 months of chemo and your cancer is still locally advanced or borderline resectable.
St Louis, MissouriAges 18 years+ - NCT07126509Recruiting
Surgery for pleural mesothelioma that cannot be fully removed
This trial tests if a partial surgery called pleurectomy can help people with a specific type of mesothelioma that cannot be fully removed. You must have already completed at least 6 weeks of chemotherapy or immunotherapy without the cancer growing.
Chicago, IllinoisAges 18 years+ - NCT07126678Recruiting
Zanubrutinib, Bendamustine, and Obinutuzumab for advanced follicular lymphoma
This trial tests a 3-drug combination (Zanubrutinib, Bendamustine, and Obinutuzumab) for people with advanced follicular lymphoma who have not had treatment before. The goal is to see if a fixed-duration treatment plan can improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT07128641RecruitingPhase 2
Odronextamab for early follicular lymphoma without prior treatment
This trial tests a new immunotherapy drug, odronextamab, for people with slow-growing follicular lymphoma that hasn't been treated yet and isn't causing big problems. It aims to see if the drug can control the cancer with fewer side effects.
Boston, MassachusettsAges 18 years+ - NCT07129993RecruitingPhase 2/Phase 3
Comparing two drug combinations for advanced bladder cancer
This trial tests a new drug combination (Dato-DXd plus chemotherapy) against a standard chemotherapy combination for advanced bladder cancer that has spread or cannot be removed by surgery. It is for people whose cancer has grown after treatment with the drugs enfortumab vedotin (Padcev) and pembrolizumab (Keytruda).
Fullerton, CaliforniaAges 18 years+ - NCT07137754Recruiting
Physiotherapy for minor injuries in the emergency department
This study tests whether a physiotherapy-led care model in the emergency department can help people with minor muscle or bone injuries recover better and at a lower cost. If you join, you'll see a physiotherapist instead of a doctor for your arm or leg injury.
Aarhus NAges 18 years+ - NCT07142226Recruiting
Liquid biopsy for advanced bile duct cancer
This trial uses a blood test called ctDNA to look at the genetic makeup of your cancer. It aims to learn more about bile duct cancer and may help guide your treatment choices.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07145255RecruitingPhase 1/Phase 2
Study of MBRC-201 for advanced solid tumors
This trial tests a new drug, MBRC-201, for people with advanced solid tumors that have not responded to standard treatments. The goal is to find the best dose and see if it helps shrink tumors or slow their growth.
San Francisco, CaliforniaAges 18 years+ - NCT07146646RecruitingPhase 2
Chemo combo for advanced bile duct cancer
This trial tests a combination of two chemotherapy drugs (trifluridine/tipiracil and oxaliplatin) for people with advanced or metastatic bile duct cancer (including gallbladder cancer) who have only had one prior treatment. The goal is to see if this combination can help control the cancer.
Cleveland, OhioAges 19 years+ - NCT07150000Recruiting
Rheumatic disease research study for patients and healthy volunteers
This study is for people with certain rheumatic conditions (like arthritis, lupus, or vasculitis) and for healthy volunteers. It aims to learn more about these diseases and improve how they are treated.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07150663RecruitingPhase 3
Megestrol acetate with chemoradiation for stage III lung cancer
This study tests whether a special form of megestrol acetate (a medicine used to help with weight and appetite) can improve outcomes when given alongside standard chemotherapy and radiation for people with stage III non-small cell lung cancer. It is for patients who are not overweight and who are not already using other appetite-boosting medications.
Wuhan, HubeiAges 18–85 - NCT07151040RecruitingPhase 1/Phase 2
Testing TH9619 for advanced solid tumors
This trial tests a new drug called TH9619 for people with advanced cancers of the colon, head and neck, lung, or stomach. It aims to see if the drug is safe and works against tumors that have already been treated with chemotherapy.
VillejuifAges 18 years+ - NCT07151118Recruiting
Blood test for advanced biliary tract cancer
This study uses a simple blood test (ctDNA) to learn more about the genetic makeup of advanced biliary tract cancers. It may help researchers understand how these cancers respond to treatment, and it doesn't involve any extra drugs or procedures—just blood draws.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07152249Recruiting
Improving nausea and vomiting care during surgery
This trial tests a new approach to prevent nausea and vomiting after surgery. It compares usual care to a structured plan that matches anti-nausea medicines to your personal risk factors.
Nashville, TennesseeAges 18 years+ - NCT07153887RecruitingPhase 2
Vebreltinib for advanced clear cell sarcoma
This trial tests the drug vebreltinib for people with advanced or spreading clear cell sarcoma. The goal is to see if it can shrink tumors and help patients live longer.
Hangzhou, ZhejiangAges 12 years+ - NCT07154316RecruitingPhase 2
Short radiation plus drugs for MSS rectal cancer
This trial tests a shorter course of radiation therapy followed by a combination of chemotherapy, immunotherapy, and a pain-relief medication, compared to the standard approach. It is for people with a certain type of rectal cancer that has not spread.
Fuzhou, FujianAges 18–75 - NCT07155226RecruitingPhase 1/Phase 2
Study of AZD3632 for advanced blood cancers with certain gene changes
This trial is testing a new drug, AZD3632, either alone or with other cancer treatments, for people with advanced blood cancers that have specific genetic changes (like KMT2Ar, NPM1m, or others that cause HOX over-expression). The goal is to see if it can help when standard treatments have stopped working.
Decatur, IllinoisAges 16 years+ - NCT07156136RecruitingPhase 1
Study of a new drug IMC-P115C for advanced PRAME-positive cancers
This trial tests an experimental drug, IMC-P115C, for people with advanced cancers that have a specific marker called PRAME and a genetic type HLA-A*02:01. It may be an option if other treatments have stopped working or caused side effects.
AdelaideAges 18 years+ - NCT07156565RecruitingPhase 1
Targeted radiation therapy for advanced sarcoma
This trial tests a new radioactive drug for people with advanced soft tissue sarcoma that has come back or not responded to prior treatment. The drug targets a protein found on sarcoma cells to deliver radiation directly to the tumor.
Los Angeles, CaliforniaAges 18 years+ - NCT07157969RecruitingPhase 2
Immunotherapy and anti-VEGF with or without local therapy for liver cancer
This trial tests a combination of immunotherapy (checkpoint inhibitors) and anti-VEGF therapy (which blocks blood vessel growth to tumors) with or without local treatments (like chemoembolization) for advanced liver cancer. It aims to see if the combination works better than current treatments.
BeijingAges 18 years+ - NCT07158541Recruiting
Comparing Two Gum Treatments for Lower Front Recession
This study compares two techniques (TCAF and MTUN) for treating a single gum recession in the lower front part of the mouth. It will help determine which method works best for healing and appearance.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07159269Recruiting
Cardiac ultrasound training for emergency department providers
This study teaches nurse practitioners and physician assistants in the emergency department how to use a special type of heart ultrasound (called cardiac point-of-care ultrasound). The goal is to help these providers quickly and accurately check the heart at the bedside.
Durham, North CarolinaAges 18 years+ - NCT07159386Recruiting
Detecting advanced liver scarring in fatty liver disease
This study tests a new screening tool to find advanced liver scarring in people with liver disease linked to diabetes. It helps doctors decide who needs more tests or specialist care.
Charleston, South CarolinaAges 18 years+ - NCT07162480RecruitingPhase 2
New drug for aggressive adenoid cystic carcinoma
This trial tests a new drug called Puxitatug Samrotecan (AZD8205) for people with an aggressive form of adenoid cystic carcinoma. It aims to see if the drug can shrink tumors or slow the disease in patients whose cancer has advanced or spread.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for advanced?
- Yes. Clin2 currently lists 3,977 recruiting advanced studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.