Clinical trials
Alzheimer s Disease clinical trials
Below are recruiting alzheimer s disease clinical trials, each written for real people, not researchers. We’re tracking 601 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06372821RecruitingPhase 1
Study of NIO752 for Alzheimer's disease
This study tests an experimental drug called NIO752 to see if it can reduce the production of tau protein, which is linked to Alzheimer's disease. Researchers will measure how the drug affects tau in your body using a special technique called SILK.
St Louis, MissouriAges 21–80 - NCT06057909Recruiting
Brain function study in Lewy body and Alzheimer's disease
This study looks at how brain function changes over time in people with Lewy body disease or Alzheimer's. Researchers will use memory tests, MRI scans, and EEG (a painless brain-wave recording) to track these changes, and you will need a family member or friend to help report on your daily life.
Scottsdale, ArizonaAges 50–95 - NCT05924425RecruitingPhase 4
Daridorexant for insomnia in early memory decline
This trial tests whether daridorexant can improve sleep in people who have mild cognitive impairment or early Alzheimer’s disease and struggle with insomnia. It may help by improving how long and how well you sleep, with monitoring of sleep patterns and memory-related measures.
MontpellierAges 60–85 - NCT05882344Enrolling by invitation
Deep brain stimulation for early Alzheimer’s memory problems
This trial tests whether a targeted deep brain stimulation treatment can help people with early Alzheimer’s disease symptoms and memory loss. It also involves brain imaging and a surgery/anesthesia procedure to place the stimulator.
Nashville, TennesseeAges 60–80 - NCT05847192Recruiting
Testing brain-signal networks in Alzheimer’s with hallucinations
This study looks at “tau” (a brain protein) and brain-signal patterns in people with Alzheimer’s disease who have psychotic symptoms like hallucinations or delusions. It may help researchers understand what’s happening in the brain and how to better target these symptoms.
Manhasset, New YorkAges 65–85 - NCT05655195Recruiting
At-home light and sound therapy for mild Alzheimer’s
This study tests whether regular at-home “gamma” light and sound stimulation can help people with mild Alzheimer’s. Participants start with a month at home and are followed to see how they do during treatment.
Cambridge, MassachusettsAges 65–100 - NCT05655650Recruiting
Finding blood or brain markers in Alzheimer’s disease
This study looks for “biomarkers,” or measurable signs, that help identify Alzheimer’s disease. It may help doctors diagnose Alzheimer’s more accurately by comparing people with Alzheimer’s to others where the diagnosis is different.
Hong Kong, Hong HongAges 20 years+ - NCT05462106RecruitingPhase 1/Phase 2
ACI-24.060 study for early Alzheimer’s in adults and Down syndrome
This Phase 1/2 study tests an Alzheimer’s treatment called ACI-24.060 to see if it affects the disease in people with early Alzheimer’s changes. It includes two groups: older adults with early symptoms and people with Down syndrome who also show Alzheimer’s-related changes on brain scans.
Phoenix, ArizonaAges 35–85 - NCT05010603Recruiting
Studies families to understand late-onset Alzheimer’s
This study focuses on people with late-onset Alzheimer’s (and some similar memory diseases) and uses a close family “informant” to share what they’ve noticed. It may help researchers learn more about these conditions and how they progress in families.
Washington D.C., District of ColumbiaAges 55 years+ - NCT03799991Recruiting
Balance therapy for people with early-to-moderate Alzheimer’s
This trial tests whether an 8-week balance and movement program can help people with early-to-moderate Alzheimer’s who also have inner-ear (vestibular) balance loss. You and a caregiver may learn exercises and attend weekly visits, while researchers compare the results to an active control program.
Baltimore, MarylandAges 60 years+ - NCT03657732Recruiting
Study of inherited Alzheimer’s genes in families
This study looks at people from families with inherited Alzheimer’s disease, including those who may be cognitively normal. It uses medical checkups and brain/nerve tests to better understand Alzheimer’s risk and symptoms in families with specific gene changes.
Hefei, AnhuiAges 18 years+ - NCT02740634Recruiting
Brain imaging study for Alzheimer's disease
This study uses brain scans to understand Alzheimer's disease and related conditions that affect memory, language, or vision. It looks at how changes in the brain happen over time in people with these diagnoses.
Rochester, MinnesotaAges 21–80 - NCT00064870Recruiting
Alzheimer's Disease Family Genetics Study
This study collects biological samples (blood or cells) from families where two or more members have been diagnosed with Alzheimer's disease or dementia. Researchers use these samples to identify genetic factors that may cause or increase risk for these conditions.
Nationwide, IndianaAges 18 years+ - NCT03082755RecruitingPhase 4
Study sleep agitation and restless legs in Alzheimer’s patients
This trial studies treatment for troubling nighttime restlessness and agitation in people with Alzheimer’s disease. It may help improve sleep and nighttime comfort and reduce nighttime behavior problems.
Austin, TexasAges 55 years+ - NCT05597410Recruiting
Study of people at risk for Alzheimer’s in Shanghai
This study follows people who are closely related to someone diagnosed with Alzheimer’s to see who develops memory or brain changes over time. It may help researchers understand risk and early signs, which could guide prevention in families like yours.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT04436081RecruitingPhase 2
CBD oil without THC for agitation in Alzheimer’s dementia
This trial studies whether a THC-free CBD oil softgel can reduce agitation in people with Alzheimer’s-related dementia. It compares CBD to a control to see if it improves difficult behaviors and is safe over the study period.
Norfolk, VirginiaAges 50–90 - NCT05984524Recruiting
Gamma music therapy for mild Alzheimer's disease
This study tests whether a specially designed music intervention can help people with mild Alzheimer's disease. You listen to music with a gamma frequency beat, which may improve brain function and memory.
Boston, MassachusettsAges 50–95 - NCT05194787Recruiting
Online tests to spot early Alzheimer’s changes
This study looks at whether online motor (movement) and thinking tasks can detect early changes related to Alzheimer’s disease. You may be able to take part if you’re over 50 and do not already have a diagnosis of dementia.
Hobart, TasmaniaAges 50 years+ - NCT07857759Recruiting
Neck lymph node surgery for early Alzheimer's disease
This study tests whether a microsurgery on lymph nodes in the neck can help clear waste from the brain in people with early Alzheimer's. It might slow down memory loss.
GdanskAges 18 years+ - NCT06442852Recruiting
Blood microRNA linked to Alzheimer's risk and severity
This study looks for tiny molecules (miRNAs) in your blood that might be linked to Alzheimer's disease risk and severity. It compares people with Alzheimer's to healthy volunteers to find potential early warning signs.
Wuhan, HubeiAges 65 years+ - NCT07787169RecruitingPhase 1
Study of amyloid-targeting therapies for Alzheimer's disease
This study tests several new experimental medications that target amyloid plaques, the protein clumps linked to Alzheimer's disease. It aims to find out if these treatments are safe and well-tolerated in people with early-stage Alzheimer's and in healthy volunteers.
Anaheim, CaliforniaAges 18–85 - NCT05509387Recruiting
Stronger brain stimulation to improve naming in Alzheimer’s
This trial tests whether a stronger form of gentle brain stimulation (tDCS) can help people with mild to moderate Alzheimer’s improve word-finding (naming). If you qualify, you’ll be assessed before and during the study to see whether the stimulation improves naming ability.
Toronto, OntarioAges 50–90 - NCT07732842Recruiting
Understanding Repetitive Behaviors in Alzheimer's Disease
This study looks at repetitive behaviors (like pacing, tapping, or repeating words) in people with Alzheimer's disease. They want to understand these behaviors better, which could help improve care and treatment.
Limoges, New AquitaineAges 18 years+ - NCT07659964Recruiting
Rhythmic music and walking study for Alzheimer's
This study tests whether listening to a steady beat (rhythmic music) while walking can improve movement and brain function in people with mild Alzheimer's disease. Healthy volunteers are also needed for comparison.
Boston, MassachusettsAges 50–90
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Common questions
- Are there clinical trials for alzheimer s disease?
- Yes. Clin2 currently lists 601 recruiting alzheimer s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.